Articles producció científica> Ciències Mèdiques Bàsiques

Antifungal and antiparasitic drug delivery

  • Dades identificatives

    Identificador: imarina:6247877
    Autors:
    Torrado JJSerrano DRCapilla J
    Resum:
    © 2020 by the authors. Licensee MDPI, Basel, Switzerland. Fungal and parasitic diseases affect more than a billion people across the globe, one-sixth of the world’s population, mostly located in developing countries. The lack of effective and safer treatments combined with a deficient diagnosis lead to serious chronic illness or even death. There is a mismatch between the rate of drug resistance and the development of new medicines. Formulation of antifungal and antiparasitic drugs adapted to different administration routes is challenging, bearing in mind their poor water solubility, which limits their bioavailability and efficacy. Hence, there is an unmet clinical need to develop vaccines and novel formulations and drug delivery strategies that can improve the bioavailability and therapeutic effect by enhancing their dissolution, increasing their chemical potency, stabilising the drug and targeting high concentration of drug to the infection sites. This Editorial regards the ten research contributions presented in the Special Issue “Antifungal and Antiparasitic Drug Delivery”.
  • Altres:

    Autor segons l'article: Torrado JJ; Serrano DR; Capilla J
    Departament: Ciències Mèdiques Bàsiques
    Autor/s de la URV: Capilla Luque, Javier
    Paraules clau: Trypanosomiasis Transferosomes Quality by design Nanoparticles Malaria Liposomes Leishmaniasis Emulsions Combined therapy Candidiasis Azoles Aspergillosis Amphotericin b transferosomes quality by design nanoparticles malaria liposomes leishmaniasis emulsions combined therapy candidiasis azoles aspergillosis amphotericin b
    Resum: © 2020 by the authors. Licensee MDPI, Basel, Switzerland. Fungal and parasitic diseases affect more than a billion people across the globe, one-sixth of the world’s population, mostly located in developing countries. The lack of effective and safer treatments combined with a deficient diagnosis lead to serious chronic illness or even death. There is a mismatch between the rate of drug resistance and the development of new medicines. Formulation of antifungal and antiparasitic drugs adapted to different administration routes is challenging, bearing in mind their poor water solubility, which limits their bioavailability and efficacy. Hence, there is an unmet clinical need to develop vaccines and novel formulations and drug delivery strategies that can improve the bioavailability and therapeutic effect by enhancing their dissolution, increasing their chemical potency, stabilising the drug and targeting high concentration of drug to the infection sites. This Editorial regards the ten research contributions presented in the Special Issue “Antifungal and Antiparasitic Drug Delivery”.
    Àrees temàtiques: Pharmacology & pharmacy Pharmaceutical science Medicina ii Farmacia Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Biotecnología
    Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 19994923
    Adreça de correu electrònic de l'autor: javier.capilla@urv.cat
    Identificador de l'autor: 0000-0002-0765-6403
    Data d'alta del registre: 2023-02-19
    Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
    Enllaç font original: https://www.mdpi.com/1999-4923/12/4/324
    Referència a l'article segons font original: Pharmaceutics. 12 (4):
    Referència de l'ítem segons les normes APA: Torrado JJ; Serrano DR; Capilla J (2020). Antifungal and antiparasitic drug delivery. Pharmaceutics, 12(4), -. DOI: 10.3390/pharmaceutics12040324
    URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
    DOI de l'article: 10.3390/pharmaceutics12040324
    Entitat: Universitat Rovira i Virgili
    Any de publicació de la revista: 2020
    Tipus de publicació: Journal Publications
  • Paraules clau:

    Pharmaceutical Science,Pharmacology & Pharmacy
    Trypanosomiasis
    Transferosomes
    Quality by design
    Nanoparticles
    Malaria
    Liposomes
    Leishmaniasis
    Emulsions
    Combined therapy
    Candidiasis
    Azoles
    Aspergillosis
    Amphotericin b
    transferosomes
    quality by design
    nanoparticles
    malaria
    liposomes
    leishmaniasis
    emulsions
    combined therapy
    candidiasis
    azoles
    aspergillosis
    amphotericin b
    Pharmacology & pharmacy
    Pharmaceutical science
    Medicina ii
    Farmacia
    Ciências biológicas iii
    Ciências biológicas ii
    Ciências biológicas i
    Biotecnología
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