Articles producció científica> Ciències Mèdiques Bàsiques

Antifungal and antiparasitic drug delivery

  • Datos identificativos

    Identificador: imarina:6247877
    Autores:
    Torrado JJSerrano DRCapilla J
    Resumen:
    © 2020 by the authors. Licensee MDPI, Basel, Switzerland. Fungal and parasitic diseases affect more than a billion people across the globe, one-sixth of the world’s population, mostly located in developing countries. The lack of effective and safer treatments combined with a deficient diagnosis lead to serious chronic illness or even death. There is a mismatch between the rate of drug resistance and the development of new medicines. Formulation of antifungal and antiparasitic drugs adapted to different administration routes is challenging, bearing in mind their poor water solubility, which limits their bioavailability and efficacy. Hence, there is an unmet clinical need to develop vaccines and novel formulations and drug delivery strategies that can improve the bioavailability and therapeutic effect by enhancing their dissolution, increasing their chemical potency, stabilising the drug and targeting high concentration of drug to the infection sites. This Editorial regards the ten research contributions presented in the Special Issue “Antifungal and Antiparasitic Drug Delivery”.
  • Otros:

    Autor según el artículo: Torrado JJ; Serrano DR; Capilla J
    Departamento: Ciències Mèdiques Bàsiques
    Autor/es de la URV: Capilla Luque, Javier
    Palabras clave: Trypanosomiasis Transferosomes Quality by design Nanoparticles Malaria Liposomes Leishmaniasis Emulsions Combined therapy Candidiasis Azoles Aspergillosis Amphotericin b transferosomes quality by design nanoparticles malaria liposomes leishmaniasis emulsions combined therapy candidiasis azoles aspergillosis amphotericin b
    Resumen: © 2020 by the authors. Licensee MDPI, Basel, Switzerland. Fungal and parasitic diseases affect more than a billion people across the globe, one-sixth of the world’s population, mostly located in developing countries. The lack of effective and safer treatments combined with a deficient diagnosis lead to serious chronic illness or even death. There is a mismatch between the rate of drug resistance and the development of new medicines. Formulation of antifungal and antiparasitic drugs adapted to different administration routes is challenging, bearing in mind their poor water solubility, which limits their bioavailability and efficacy. Hence, there is an unmet clinical need to develop vaccines and novel formulations and drug delivery strategies that can improve the bioavailability and therapeutic effect by enhancing their dissolution, increasing their chemical potency, stabilising the drug and targeting high concentration of drug to the infection sites. This Editorial regards the ten research contributions presented in the Special Issue “Antifungal and Antiparasitic Drug Delivery”.
    Áreas temáticas: Pharmacology & pharmacy Pharmaceutical science Medicina ii Farmacia Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Biotecnología
    Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 19994923
    Direcció de correo del autor: javier.capilla@urv.cat
    Identificador del autor: 0000-0002-0765-6403
    Fecha de alta del registro: 2023-02-19
    Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
    Enlace a la fuente original: https://www.mdpi.com/1999-4923/12/4/324
    Referencia al articulo segun fuente origial: Pharmaceutics. 12 (4):
    Referencia de l'ítem segons les normes APA: Torrado JJ; Serrano DR; Capilla J (2020). Antifungal and antiparasitic drug delivery. Pharmaceutics, 12(4), -. DOI: 10.3390/pharmaceutics12040324
    URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
    DOI del artículo: 10.3390/pharmaceutics12040324
    Entidad: Universitat Rovira i Virgili
    Año de publicación de la revista: 2020
    Tipo de publicación: Journal Publications
  • Palabras clave:

    Pharmaceutical Science,Pharmacology & Pharmacy
    Trypanosomiasis
    Transferosomes
    Quality by design
    Nanoparticles
    Malaria
    Liposomes
    Leishmaniasis
    Emulsions
    Combined therapy
    Candidiasis
    Azoles
    Aspergillosis
    Amphotericin b
    transferosomes
    quality by design
    nanoparticles
    malaria
    liposomes
    leishmaniasis
    emulsions
    combined therapy
    candidiasis
    azoles
    aspergillosis
    amphotericin b
    Pharmacology & pharmacy
    Pharmaceutical science
    Medicina ii
    Farmacia
    Ciências biológicas iii
    Ciências biológicas ii
    Ciências biológicas i
    Biotecnología
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