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New Metrics to Assess Type 2 Diabetes after Bariatric Surgery: The Time-Within-Remission Range

  • Dades identificatives

    Identificador: imarina:6310791
    Autors:
    de Hollanda, AnaLecube, AlbertAngel Rubio, MiguelSanchez, EnricVilarrasa, NuriaGregorio Oliva, JoseLuisa Fernandez-Soto, MariaSalas-Salvado, JordiBallesteros-Pomar, Maria D.Ciudin, AndreeaTorres, FerranVidal, ConcepcionJose Morales, MariaValdes, SergioPellitero, SilviaMinambres, InkaMasmiquel, LluisGoday, AlbertSuarez, LorenaFlores, LiliamBueno, MartaCaixas, AssumptaBreton, IreneCamara, RosaOlbeyra, RominaPenso, RonaJose de la Cruz, MariaSimo-Servat, AndreuMaria Pereyra-Garcia, FranciscaTeresa Lopez-Mezquita, ElenaGils, AnnaFidilio, EnzamariaBandres, OrosiaMartinez, AngelAbuin, JoseMarques-Pamies, MontserratTuneu, LauraArteaga, MagdalenaCastaner, OlgaGoni, FernandoArrizabalaga, CristinaAntonio Botana, ManuelCalanas, AlfonsoRebollo, Angel
    Resum:
    Almost one third of patients do not achieve type 2 diabetes remission after bariatric surgery or are unable to sustain this effect long term. Our objective was to delve further into the dynamic responses of diabetes after bariatric surgery and to evaluate the time-within-remission range as a variable of metabolic control. A descriptive cohort study was done using a computerised multicentre and multidisciplinary registry. All data were adjusted by propensity score. A total of 1186 subjects with a follow-up of 4.5 +/- 2.5 years were included. Type of surgery, diabetes remission, recurrence of diabetes, time-within-remission range and key predictors of diabetes outcomes were assessed. All patients (70% women, 51.4 +/- 9.2 years old, body mass index (BMI) 46.3 +/- 6.9 kg/m(2)) underwent primary bariatric procedures. Time-within-remission range were 83.3% (33.3-91.6) after gastric bypass, 68.7% (7.1-87.5) after sleeve gastrectomy and 90% (83.3-92.8) after malabsorptive techniques (p < 0.001 for all). Duration of diabetes, baseline HbA1c and insulin treatment were significantly negatively correlated with the time-within-remission range. The association of bariatric techniques with time-within-remission range, using gastric bypass as a reference, were: odds ratio (OR) 3.70 (2.34-5.84), p < 0.001 for malabsorptive techniques and OR 0.55 (0.40-0.75), p < 0.001 for sleeve gastrectomy. Characteristics of type 2 diabetes powerfully influence the outcomes of bariatric surgery. The time-within-remission range unveils a superiority of gastric bypass compared to sleeve gastrectomy.
  • Altres:

    Autor segons l'article: de Hollanda, Ana; Lecube, Albert; Angel Rubio, Miguel; Sanchez, Enric; Vilarrasa, Nuria; Gregorio Oliva, Jose; Luisa Fernandez-Soto, Maria; Salas-Salvado, Jordi; Ballesteros-Pomar, Maria D.; Ciudin, Andreea; Torres, Ferran; Vidal, Concepcion; Jose Morales, Maria; Valdes, Sergio; Pellitero, Silvia; Minambres, Inka; Masmiquel, Lluis; Goday, Albert; Suarez, Lorena; Flores, Liliam; Bueno, Marta; Caixas, Assumpta; Breton, Irene; Camara, Rosa; Olbeyra, Romina; Penso, Rona; Jose de la Cruz, Maria; Simo-Servat, Andreu; Maria Pereyra-Garcia, Francisca; Teresa Lopez-Mezquita, Elena; Gils, Anna; Fidilio, Enzamaria; Bandres, Orosia; Martinez, Angel; Abuin, Jose; Marques-Pamies, Montserrat; Tuneu, Laura; Arteaga, Magdalena; Castaner, Olga; Goni, Fernando; Arrizabalaga, Cristina; Antonio Botana, Manuel; Calanas, Alfonso; Rebollo, Angel;
    Departament: Bioquímica i Biotecnologia
    Autor/s de la URV: Salas Salvadó, Jorge
    Paraules clau: Y-gastric bypass Weight-loss Type 2 diabetes Time-within-remission range Propensity score methods Obesity Metabolic surgery Metabolic control Laparoscopic sleeve gastrectomy Follow-up Bariatric surgery time-within-remission range metabolic control bariatric surgery
    Resum: Almost one third of patients do not achieve type 2 diabetes remission after bariatric surgery or are unable to sustain this effect long term. Our objective was to delve further into the dynamic responses of diabetes after bariatric surgery and to evaluate the time-within-remission range as a variable of metabolic control. A descriptive cohort study was done using a computerised multicentre and multidisciplinary registry. All data were adjusted by propensity score. A total of 1186 subjects with a follow-up of 4.5 +/- 2.5 years were included. Type of surgery, diabetes remission, recurrence of diabetes, time-within-remission range and key predictors of diabetes outcomes were assessed. All patients (70% women, 51.4 +/- 9.2 years old, body mass index (BMI) 46.3 +/- 6.9 kg/m(2)) underwent primary bariatric procedures. Time-within-remission range were 83.3% (33.3-91.6) after gastric bypass, 68.7% (7.1-87.5) after sleeve gastrectomy and 90% (83.3-92.8) after malabsorptive techniques (p < 0.001 for all). Duration of diabetes, baseline HbA1c and insulin treatment were significantly negatively correlated with the time-within-remission range. The association of bariatric techniques with time-within-remission range, using gastric bypass as a reference, were: odds ratio (OR) 3.70 (2.34-5.84), p < 0.001 for malabsorptive techniques and OR 0.55 (0.40-0.75), p < 0.001 for sleeve gastrectomy. Characteristics of type 2 diabetes powerfully influence the outcomes of bariatric surgery. The time-within-remission range unveils a superiority of gastric bypass compared to sleeve gastrectomy.
    Àrees temàtiques: Medicine, general & internal Medicine (miscellaneous) Medicine (all)
    Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
    Adreça de correu electrònic de l'autor: jordi.salas@urv.cat
    Identificador de l'autor: 0000-0003-2700-7459
    Data d'alta del registre: 2024-09-07
    Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
    Enllaç font original: https://www.mdpi.com/2077-0383/9/4/1070
    URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
    Referència a l'article segons font original: Journal Of Clinical Medicine. 9 (4):
    Referència de l'ítem segons les normes APA: de Hollanda, Ana; Lecube, Albert; Angel Rubio, Miguel; Sanchez, Enric; Vilarrasa, Nuria; Gregorio Oliva, Jose; Luisa Fernandez-Soto, Maria; Salas-Salv (2020). New Metrics to Assess Type 2 Diabetes after Bariatric Surgery: The Time-Within-Remission Range. Journal Of Clinical Medicine, 9(4), -. DOI: 10.3390/jcm9041070
    DOI de l'article: 10.3390/jcm9041070
    Entitat: Universitat Rovira i Virgili
    Any de publicació de la revista: 2020
    Tipus de publicació: Journal Publications
  • Paraules clau:

    Medicine (Miscellaneous),Medicine, General & Internal
    Y-gastric bypass
    Weight-loss
    Type 2 diabetes
    Time-within-remission range
    Propensity score methods
    Obesity
    Metabolic surgery
    Metabolic control
    Laparoscopic sleeve gastrectomy
    Follow-up
    Bariatric surgery
    time-within-remission range
    metabolic control
    bariatric surgery
    Medicine, general & internal
    Medicine (miscellaneous)
    Medicine (all)
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