Autor segons l'article: Blade, Cinta; Baselga-Escudero, Laura; Josepa Salvado, Maria; Arola-Arnal, Anna
Departament: Bioquímica i Biotecnologia
Autor/s de la URV: Arola Arnal, Anna / BASELGA ESCUDERO, LAURA / BLADÉ SEGARRA, MARIA CINTA / Salvadó Rovira, Maria Josepa
Paraules clau: Polyphenols Obesity Non-alcoholic fatty liver disease Micrornas Microrna Lipid metabolism Insulin Humans Glucose Gene expression regulation Fatty liver Diabetes mellitus, type 2 Chronic disease Cardiovascular diseases Cardiovascular Biomarkers Amino acids Adipogenesis
Resum: MicroRNAs (miRNAs) are small noncoding RNAs, approximately 18-25 nucleotides in length, that modulate gene expression at the posttranscriptional level. Thousands of miRNAs have been described, and it is thought that they regulate some aspects of more than 60% of all human cell transcripts. Several polyphenols have been shown to modulate miRNAs related to metabolic homeostasis and chronic diseases. Polyphenolic modulation of miRNAs is very attractive as a strategy to target numerous cell processes and potentially reduce the risk of chronic disease. Evidence is building that polyphenols can target specific miRNAs, such as miR-122, but more studies are necessary to discover and validate additional miRNA targets. © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Àrees temàtiques: Saúde coletiva Química Nutrição Medicina veterinaria Medicina ii Medicina i Interdisciplinar Food science & technology Food science Farmacia Educação física Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Biotecnología Biotechnology Astronomia / física
Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 16134125
Adreça de correu electrònic de l'autor: anna.arola@urv.cat
Identificador de l'autor: 0000-0001-6529-1345
Data d'alta del registre: 2025-01-28
Versió de l'article dipositat: info:eu-repo/semantics/submittedVersion
URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
Referència a l'article segons font original: Molecular Nutrition & Food Research. 57 (1): 58-70
Referència de l'ítem segons les normes APA: Blade, Cinta; Baselga-Escudero, Laura; Josepa Salvado, Maria; Arola-Arnal, Anna (2013). miRNAs, polyphenols, and chronic disease. Molecular Nutrition & Food Research, 57(1), 58-70. DOI: 10.1002/mnfr.201200454
Entitat: Universitat Rovira i Virgili
Any de publicació de la revista: 2013
Tipus de publicació: Journal Publications
Repositori URV