Articles producció científica> Enginyeria Química

Current Perspectives of the Applications of Polyphenols and Flavonoids in Cancer Therapy

  • Dades identificatives

    Identificador: imarina:7238102
    Autors:
    Montané, XKowalczyk, OReig-Vano, BBajek, ARoszkowski, KTomczyk, RPawliszak, WGiamberini, MMocek-Plóciniak, ATylkowski, B
    Resum:
    The development of anticancer therapies that involve natural drugs has undergone exponential growth in recent years. Among the natural compounds that produce beneficial effects on human health, polyphenols have shown potential therapeutic applications in cancer due to their protective functions in plants, their use as food additives, and their excellent antioxidant properties. The possibility of combining conventional drugs-which are usually more aggressive than natural compounds-with polyphenols offers very valuable advantages such as the building of more efficient anticancer therapies with less side effects on human health. This review shows a wide range of trials in which polyphenolic compounds play a crucial role as anticancer medicines alone or in combination with other drugs at different stages of cancer: cancer initiation, promotion, and growth or progression. Moreover, the future directions in applications of various polyphenols in cancer therapy are emphasized.
  • Altres:

    Autor segons l'article: Montané, X; Kowalczyk, O; Reig-Vano, B; Bajek, A; Roszkowski, K; Tomczyk, R; Pawliszak, W; Giamberini, M; Mocek-Plóciniak, A; Tylkowski, B
    Departament: Enginyeria Química
    Autor/s de la URV: Giamberini, Marta / Montané Montané, Xavier / Reig Vañó, Belén / Tylkowski, Bartosz
    Paraules clau: Tumor-growth Prostate-cancer Polyphenols Phytochemicals P-coumaric acid Neoplasms Natural health products Molecular-mechanisms Inhibits proliferation In-vitro Humans Flavonoids Ellagic acid Drug-resistance Drug therapy Drug synergism Dietary supplements Cell lung-cancer Cancer Apoptosis Antioxidants Antineoplastic agents Anticancer therapy phytochemicals natural health products flavonoids dietary supplements cancer antioxidants anticancer therapy
    Resum: The development of anticancer therapies that involve natural drugs has undergone exponential growth in recent years. Among the natural compounds that produce beneficial effects on human health, polyphenols have shown potential therapeutic applications in cancer due to their protective functions in plants, their use as food additives, and their excellent antioxidant properties. The possibility of combining conventional drugs-which are usually more aggressive than natural compounds-with polyphenols offers very valuable advantages such as the building of more efficient anticancer therapies with less side effects on human health. This review shows a wide range of trials in which polyphenolic compounds play a crucial role as anticancer medicines alone or in combination with other drugs at different stages of cancer: cancer initiation, promotion, and growth or progression. Moreover, the future directions in applications of various polyphenols in cancer therapy are emphasized.
    Àrees temàtiques: Zootecnia / recursos pesqueiros Saúde coletiva Química Psicología Planejamento urbano e regional / demografia Physical and theoretical chemistry Pharmaceutical science Organic chemistry Odontología Nutrição Molecular medicine Medicine (miscellaneous) Medicina veterinaria Medicina iii Medicina ii Medicina i Materiais Matemática / probabilidade e estatística Interdisciplinar Geografía General medicine Farmacia Ensino Engenharias iv Engenharias iii Engenharias ii Engenharias i Educação física Economia Drug discovery Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Ciência da computação Chemistry, organic Chemistry, multidisciplinary Chemistry (miscellaneous) Biotecnología Biodiversidade Biochemistry & molecular biology Astronomia / física Analytical chemistry
    Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 1420-3049
    Adreça de correu electrònic de l'autor: xavier.montane@urv.cat bartosz.tylkowski@urv.cat marta.giamberini@urv.cat belen.reig@estudiants.urv.cat belen.reig@estudiants.urv.cat
    Identificador de l'autor: 0000-0002-1426-239X 0000-0002-4163-0178 0000-0001-8278-3552 0000-0001-6402-4499 0000-0001-6402-4499
    Data d'alta del registre: 2024-06-28
    Volum de revista: 25
    Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
    Enllaç font original: https://www.mdpi.com/1420-3049/25/15/3342
    Referència a l'article segons font original: Molecules. 25 (15): E3342-
    Referència de l'ítem segons les normes APA: Montané, X; Kowalczyk, O; Reig-Vano, B; Bajek, A; Roszkowski, K; Tomczyk, R; Pawliszak, W; Giamberini, M; Mocek-Plóciniak, A; Tylkowski, B (2020). Current Perspectives of the Applications of Polyphenols and Flavonoids in Cancer Therapy. Molecules, 25(15), E3342-. DOI: 10.3390/molecules25153342
    URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
    DOI de l'article: 10.3390/molecules25153342
    Entitat: Universitat Rovira i Virgili
    Any de publicació de la revista: 2020
    Tipus de publicació: Journal Publications
  • Paraules clau:

    Analytical Chemistry,Biochemistry & Molecular Biology,Chemistry (Miscellaneous),Chemistry, Multidisciplinary,Chemistry, Organic,Drug Discovery,Medicine (Miscellaneous),Molecular Medicine,Organic Chemistry,Pharmaceutical Science,Physical and Theoretical Chemistry
    Tumor-growth
    Prostate-cancer
    Polyphenols
    Phytochemicals
    P-coumaric acid
    Neoplasms
    Natural health products
    Molecular-mechanisms
    Inhibits proliferation
    In-vitro
    Humans
    Flavonoids
    Ellagic acid
    Drug-resistance
    Drug therapy
    Drug synergism
    Dietary supplements
    Cell lung-cancer
    Cancer
    Apoptosis
    Antioxidants
    Antineoplastic agents
    Anticancer therapy
    phytochemicals
    natural health products
    flavonoids
    dietary supplements
    cancer
    antioxidants
    anticancer therapy
    Zootecnia / recursos pesqueiros
    Saúde coletiva
    Química
    Psicología
    Planejamento urbano e regional / demografia
    Physical and theoretical chemistry
    Pharmaceutical science
    Organic chemistry
    Odontología
    Nutrição
    Molecular medicine
    Medicine (miscellaneous)
    Medicina veterinaria
    Medicina iii
    Medicina ii
    Medicina i
    Materiais
    Matemática / probabilidade e estatística
    Interdisciplinar
    Geografía
    General medicine
    Farmacia
    Ensino
    Engenharias iv
    Engenharias iii
    Engenharias ii
    Engenharias i
    Educação física
    Economia
    Drug discovery
    Ciências biológicas iii
    Ciências biológicas ii
    Ciências biológicas i
    Ciências ambientais
    Ciências agrárias i
    Ciência de alimentos
    Ciência da computação
    Chemistry, organic
    Chemistry, multidisciplinary
    Chemistry (miscellaneous)
    Biotecnología
    Biodiversidade
    Biochemistry & molecular biology
    Astronomia / física
    Analytical chemistry
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