Articles producció científica> Química Analítica i Química Orgànica

Paper-based Potentiometric Biosensor for Monitoring Galactose in Whole Blood

  • Dades identificatives

    Identificador: imarina:8504701
    Autors:
    Bouri, MohamedZuaznabar-Gardona, Julio C.Novell, MartaBlondeau, PascalAndrade, Francisco J.
    Resum:
    A filter paper sputtered with a layer of Pt and subsequently coated with a Nafion (R) membrane is used as working electrode. The mixed potential of the Pt electrode allows the detection of H2O2 generated by the oxidation of galactose in the presence of the galactose oxidase enzyme. This provides a simple and mediator-free approach method. The system shows sensitivity values of -62.8 +/- 9.4 mV/decade of galactose in the range from 0.3 to 31.6 mM, well within the clinical relevant range. MnO2 nanoparticles were added to decrease the interference from ascorbic acid so that validation of the sensor in whole blood samples was performed with good recovery.
  • Altres:

    e-ISSN: 1521-4109
    Codi de projecte: CTQ2016-77128-R
    Paraules clau: Screen Potentiometry Paper-based platform Mno2 Mixed potential Glucose Galactosemia Electrodes Diagnosis Cell Biosensor
    Data d'alta del registre: 2024-07-27
    Versió de l'article dipositat: info:eu-repo/semantics/acceptedVersion
    URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
    Referència a l'article segons font original: Electroanalysis. 33 (1): 81-89
    Referència de l'ítem segons les normes APA: Bouri, Mohamed; Zuaznabar-Gardona, Julio C.; Novell, Marta; Blondeau, Pascal; Andrade, Francisco J.; (2021). Paper-based Potentiometric Biosensor for Monitoring Galactose in Whole Blood. Electroanalysis, 33(1), 81-89. DOI: 10.1002/elan.202060285
    Acrònim: HOMESENS
    Tipus de publicació: Journal Publications
    Autor segons l'article: Bouri, Mohamed; Zuaznabar-Gardona, Julio C.; Novell, Marta; Blondeau, Pascal; Andrade, Francisco J.;
    Departament: Química Analítica i Química Orgànica
    Acrònim 2: SMARTCHEM
    Autor/s de la URV: Andrade, Francisco Javier / Blondeau, Pascal Jean Claude Leon / NOVELL RECASENS, MARTA / ZUAZNABAR GARDONA, JULIO CÉSAR
    Resum: A filter paper sputtered with a layer of Pt and subsequently coated with a Nafion (R) membrane is used as working electrode. The mixed potential of the Pt electrode allows the detection of H2O2 generated by the oxidation of galactose in the presence of the galactose oxidase enzyme. This provides a simple and mediator-free approach method. The system shows sensitivity values of -62.8 +/- 9.4 mV/decade of galactose in the range from 0.3 to 31.6 mM, well within the clinical relevant range. MnO2 nanoparticles were added to decrease the interference from ascorbic acid so that validation of the sensor in whole blood samples was performed with good recovery.
    Acció del programa de finançament 2: Proyecto de I+D+i RTI Tipo B
    Àrees temàtiques: Saúde coletiva Química Psicología Medicina ii Medicina i Materiais Interdisciplinar Geociências Farmacia Engenharias iii Engenharias ii Electrochemistry Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Chemistry, analytical Biotecnología Biodiversidade Astronomia / física Analytical chemistry
    Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 1040-0397
    Adreça de correu electrònic de l'autor: pascal.blondeau@urv.cat franciscojavier.andrade@urv.cat
    Identificador de l'autor: 0000-0003-1331-5055 0000-0003-1199-2837
    Codi del projecte 2: PID2019-106862RB-I00
    Programa de finançament 2: Programa Estatal De Generación De Conocimiento Y Fortalecimiento Científico y Tecnológico Del Sistema De I+D+i y del Programa Estatal De I+D+i Orientada los Retos de la Sociedad (Agencia Estatal de Investigación - Ministerio de Ciencia e Innovación).
    Programa de finançament: Programa Estatal de Investigación, Desarrollo e Innovación Orientada a los Retos de la Sociedad (Agencia Estatal de Investigación - Ministerio de Economía, Industria y Competitividad)
    Entitat: Universitat Rovira i Virgili
    Any de publicació de la revista: 2021
    Acció del programa de finançament: Proyecto de I+D
  • Paraules clau:

    Analytical Chemistry,Chemistry, Analytical,Electrochemistry
    Screen
    Potentiometry
    Paper-based platform
    Mno2
    Mixed potential
    Glucose
    Galactosemia
    Electrodes
    Diagnosis
    Cell
    Biosensor
    Saúde coletiva
    Química
    Psicología
    Medicina ii
    Medicina i
    Materiais
    Interdisciplinar
    Geociências
    Farmacia
    Engenharias iii
    Engenharias ii
    Electrochemistry
    Ciências biológicas ii
    Ciências biológicas i
    Ciências ambientais
    Ciências agrárias i
    Chemistry, analytical
    Biotecnología
    Biodiversidade
    Astronomia / física
    Analytical chemistry
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