Autor segons l'article: Iftimie, S; López-Azcona, AF; Vallverdú, I; Hernández-Flix, S; de Febrer, G; Parra, S; Hernández-Aguilera, A; Riu, F; Joven, J; Andreychuk, N; Baiges-Gaya, G; Ballester, F; Benavent, M; Burdeos, J; Català, A; Castañé, E; Castañé, H; Colom, J; Feliu, M; Gabaldó, X; Garrido, D; Garrido, P; Gil, J; Guelbenzu, P; Lozano, C; Marimon, F; Pardo, P; Pujol, I; Rabassa, A; Revuelta, L; Ríos, M; Rius-Gordillo, N; Rodríguez-Tomàs, E; Rojewski, W; Roquer-Fanlo, E; Sabaté, N; Teixidó, A; Vasco, C; Camps, J; Castro, A
Departament: Bioquímica i Biotecnologia
Autor/s de la URV: Alkhoury, Nadine / Andreychuk Pasichna, Natalia / Baiges Gaya, Gerard / Ballester Bastardie, Frederic / Camps Andreu, Jorge / Castañé Vilafranca, Helena / Castro Salomó, Antoni / Colom De Ossó, Josep Enric / Feliu Masgoret, Mireia / GIL ALUJA, JAIME / Hernández Flix, Salvador José / Iftimie Iftimie, Simona Mihaela / Joven Maried, Jorge / L
Paraules clau: Western europe Treatment outcome Tocilizumab Therapy Symptomatology Spain Southern europe Risk factor Remdesivir Puerperium Prospective study Pregnant woman Pneumonia Pediatric patient Pandemics Pandemic Oxygen therapy Noninvasive ventilation Nonhuman Non insulin dependent diabetes mellitus Neurologic disease Mortality risk Middle aged Male Major clinical study Lopinavir plus ritonavir Kidney disease Hydroxychloroquine Humans Human Hospitalization Hospital patient Gastrointestinal symptom Fever Female Epidemiology Dyspnea Disease severity Disease duration Covid-19 Coughing Corticosteroid Coronavirus disease 2019 Controlled study Comparative study Comorbidity Case fatality rate Cardiovascular disease Article Anticoagulant agent Aged
Resum: Many countries have seen a two-wave pattern in reported cases of coronavirus disease-19 during the 2020 pandemic, with a first wave during spring followed by the current second wave in late summer and autumn. Empirical data show that the characteristics of the effects of the virus do vary between the two periods. Differences in age range and severity of the disease have been reported, although the comparative characteristics of the two waves still remain largely unknown. Those characteristics are compared in this study using data from two equal periods of 3 and a half months. The first period, between 15(th) March and 30(th) June, corresponding to the entire first wave, and the second, between 1(st) July and 15(th) October, corresponding to part of the second wave, still present at the time of writing this article. Two hundred and four patients were hospitalized during the first period, and 264 during the second period. Patients in the second wave were younger and the duration of hospitalization and case fatality rate were lower than those in the first wave. In the second wave, there were more children, and pregnant and post-partum women. The most frequent signs and symptoms in both waves were fever, dyspnea, pneumonia, and cough, and the most relevant comorbidities were cardiovascular diseases, type 2 diabetes mellitus, and chronic neurological diseases. Patients from the second wave more frequently presented renal and gastrointestinal symptoms, were more often treated with non-invasive mechanical ventilation and corticoids, and less often with invasive mechanical ventilation, conventional oxygen therapy and anticoagulants. Several differences in mortality risk factors were also observed. These results might help to understand the characteristics of the second wave and the behaviour and danger of SARS-CoV-2 in the Mediterranean area and in Western Europe. Further studies are needed to confirm our findings.
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Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
Adreça de correu electrònic de l'autor: franciscopedro.riu@urv.cat simonamihaela.iftime@urv.cat pedroantonio.pardo@urv.cat neus.sabate@urv.cat carlosarturo.vasco@urv.cat natalia.andreychuk@urv.cat mireia.feliu@urv.cat francesc.marimon@urv.cat antonio.rabassa@urv.cat josepenric.colom@urv.cat inmaculada.vallverdu@urv.cat salvadorjose.hernandez@urv.cat jorge.camps@urv.cat nadine.alkhoury@estudiants.urv.cat nadine.alkhoury@estudiants.urv.cat nadine.alkhoury@estudiants.urv.cat nadine.alkhoury@estudiants.urv.cat neus.sabate@urv.cat helena.castane@estudiants.urv.cat gerard.baiges@estudiants.urv.cat elisabet.rodriguezt@estudiants.urv.cat elisabet.rodriguezt@estudiants.urv.cat sandra.parra@urv.cat jorge.joven@urv.cat antoni.castro@urv.cat isabel.pujol@urv.cat carles.lozano@urv.cat carles.lozano@urv.cat frederic.ballester@estudiants.urv.cat
Identificador de l'autor: 0000-0003-0714-8414 0000-0002-3165-3640 0000-0001-9363-6574 0000-0003-2749-4541 0000-0001-5441-6333
Data d'alta del registre: 2024-07-27
Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
Enllaç font original: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0248029
URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
Referència a l'article segons font original: Plos One. 16 (3): e0248029-
Referència de l'ítem segons les normes APA: Iftimie, S; López-Azcona, AF; Vallverdú, I; Hernández-Flix, S; de Febrer, G; Parra, S; Hernández-Aguilera, A; Riu, F; Joven, J; Andreychuk, N; Baiges- (2021). First and second waves of coronavirus disease-19: A comparative study in hospitalized patients in Reus, Spain. Plos One, 16(3), e0248029-. DOI: 10.1371/journal.pone.0248029
DOI de l'article: 10.1371/journal.pone.0248029
Entitat: Universitat Rovira i Virgili
Any de publicació de la revista: 2021
Tipus de publicació: Journal Publications
Repositori URV