Autor según el artículo: Iftimie, Simona; Lopez-Azcona, Ana F; Vallverdu, Immaculada; Hernandez-Flix, Salvador; de Febrer, Gabriel; Parra, Sandra; Hernandez-Aguilera, Anna; Riu, Francesc; Joven, Jorge; Andreychuk, Natalia; Baiges-Gaya, Gerard; Ballester, Frederic; Benavent, Marc; Burdeos, Jose; Catala, Alba; Castane, Eric; Castane, Helena; Colom, Josep; Feliu, Mireia; Gabaldo, Xavier; Garrido, Diana; Garrido, Pedro; Gil, Joan; Guelbenzu, Paloma; Lozano, Carolina; Marimon, Francesc; Pardo, Pedro; Pujol, Isabel; Rabassa, Antoni; Revuelta, Laia; Rios, Marta; Rodriguez-Tomas, Elisabet; Rojewski, Wojciech; Roquer-Fanlo, Esther; Sabate, Noelia; Teixido, Anna; Vasco, Carlos; Camps, Jordi; Castro, Antoni
Departamento: Bioquímica i Biotecnologia
Autor/es de la URV: Alkhoury, Nadine / Andreychuk Pasichna, Natalia / Baiges Gaya, Gerard / Ballester Bastardie, Frederic / Camps Andreu, Jorge / Castañé Vilafranca, Helena / Castro Salomó, Antoni / Colom De Ossó, Josep Enric / Feliu Masgoret, Mireia / GIL ALUJA, JAIME / Hernández Flix, Salvador José / Iftimie Iftimie, Simona Mihaela / Joven Maried, Jorge / L
Palabras clave: Western europe; Treatment outcome; Tocilizumab; Therapy; Symptomatology; Spain; Southern europe; Risk factor; Remdesivir; Puerperium; Prospective study; Pregnant woman; Pneumonia; Pediatric patient; Pandemics; Pandemic; Oxygen therapy; Noninvasive ventilation; Nonhuman; Non insulin dependent diabetes mellitus; Neurologic disease; Mortality risk; Middle aged; Male; Major clinical study; Lopinavir plus ritonavir; Kidney disease; Hydroxychloroquine; Humans; Human; Hospitalization; Hospital patient; Gastrointestinal symptom; Fever; Female; Epidemiology; Dyspnea; Disease severity; Disease duration; Covid-19; Coughing; Corticosteroid; Coronavirus disease 2019; Controlled study; Comparative study; Comorbidity; Case fatality rate; Cardiovascular disease; Article; Anticoagulant agent; Aged
Resumen: Many countries have seen a two-wave pattern in reported cases of coronavirus disease-19 during the 2020 pandemic, with a first wave during spring followed by the current second wave in late summer and autumn. Empirical data show that the characteristics of the effects of the virus do vary between the two periods. Differences in age range and severity of the disease have been reported, although the comparative characteristics of the two waves still remain largely unknown. Those characteristics are compared in this study using data from two equal periods of 3 and a half months. The first period, between 15(th) March and 30(th) June, corresponding to the entire first wave, and the second, between 1(st) July and 15(th) October, corresponding to part of the second wave, still present at the time of writing this article. Two hundred and four patients were hospitalized during the first period, and 264 during the second period. Patients in the second wave were younger and the duration of hospitalization and case fatality rate were lower than those in the first wave. In the second wave, there were more children, and pregnant and post-partum women. The most frequent signs and symptoms in both waves were fever, dyspnea, pneumonia, and cough, and the most relevant comorbidities were cardiovascular diseases, type 2 diabetes mellitus, and chronic neurological diseases. Patients from the second wave more frequently presented renal and gastrointestinal symptoms, were more often treated with non-invasive mechanical ventilation and corticoids, and less often with invasive mechanical ventilation, conventional oxygen therapy and anticoagulants. Several differences in mortality risk factors were also observed. These results might help to understand the characteristics of the second wave and the behaviour and danger of SARS-CoV-2 in the Mediterranean area and in Western Europe. Further studies are needed to confirm our findings.
Áreas temáticas: Zootecnia / recursos pesqueiros; Sociology; Sociología; Serviço social; Saúde coletiva; Química; Psychology; Psicología; Planejamento urbano e regional / demografia; Odontología; Nutrição; Multidisciplinary sciences; Multidisciplinary; Medicine (miscellaneous); Medicina veterinaria; Medicina iii; Medicina ii; Medicina i; Materiais; Matemática / probabilidade e estatística; Linguística e literatura; Letras / linguística; Interdisciplinary research in the social sciences; Interdisciplinar; Human geography and urban studies; History & philosophy of science; Historia; Geografía; Geociências; General medicine; General biochemistry,genetics and molecular biology; General agricultural and biological sciences; Farmacia; Environmental studies; Ensino; Engenharias iv; Engenharias iii; Engenharias ii; Engenharias i; Enfermagem; Educação física; Educação; Economia; Direito; Demography; Comunicação e informação; Ciências sociais aplicadas i; Ciências biológicas iii; Ciências biológicas ii; Ciências biológicas i; Ciências ambientais; Ciências agrárias i; Ciência política e relações internacionais; Ciência de alimentos; Ciência da computação; Biotecnología; Biology; Biodiversidade; Biochemistry, genetics and molecular biology (miscellaneous); Astronomia / física; Arquitetura, urbanismo e design; Archaeology; Antropologia / arqueologia; Anthropology; Agricultural and biological sciences (miscellaneous); Administração, ciências contábeis e turismo; Administração pública e de empresas, ciências contábeis e turismo
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
Direcció de correo del autor: neus.sabate@urv.cat; carlosarturo.vasco@urv.cat; natalia.andreychuk@urv.cat; mireia.feliu@urv.cat; francesc.marimon@urv.cat; antonio.rabassa@urv.cat; josepenric.colom@urv.cat; franciscopedro.riu@urv.cat; simonamihaela.iftime@urv.cat; inmaculada.vallverdu@urv.cat; salvadorjose.hernandez@urv.cat; pedroantonio.pardo@urv.cat; jorge.camps@urv.cat; nadine.alkhoury@estudiants.urv.cat; nadine.alkhoury@estudiants.urv.cat; nadine.alkhoury@estudiants.urv.cat; nadine.alkhoury@estudiants.urv.cat; neus.sabate@urv.cat; helena.castane@estudiants.urv.cat; gerard.baiges@estudiants.urv.cat; elisabet.rodriguezt@estudiants.urv.cat; elisabet.rodriguezt@estudiants.urv.cat; sandra.parra@urv.cat; jorge.joven@urv.cat; antoni.castro@urv.cat; isabel.pujol@urv.cat; carles.lozano@urv.cat; carles.lozano@urv.cat; frederic.ballester@estudiants.urv.cat
Fecha de alta del registro: 2025-01-04
Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
Enlace a la fuente original: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0248029
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
Referencia al articulo segun fuente origial: Plos One. 16 (3): e0248029-
Referencia de l'ítem segons les normes APA: Iftimie, Simona; Lopez-Azcona, Ana F; Vallverdu, Immaculada; Hernandez-Flix, Salvador; de Febrer, Gabriel; Parra, Sandra; Hernandez-Aguilera, Anna; Ri (2021). First and second waves of coronavirus disease-19: A comparative study in hospitalized patients in Reus, Spain. Plos One, 16(3), e0248029-. DOI: 10.1371/journal.pone.0248029
DOI del artículo: 10.1371/journal.pone.0248029
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2021
Tipo de publicación: Journal Publications
Repositori URV