Articles producció científica> Psicologia

Modifiable Risk Factors for Dementia: The Role of Gut Microbiota

  • Dades identificatives

    Identificador: imarina:9241699
    Autors:
    Cabrera, CristianVicens, PalomaTorrente, Margarita
    Resum:
    :Dementia is a syndrome resulting from chronic or progressive brain disease. Around 40% of worldwide dementia can be prevented or delayed by modifying 12 risk factors: low educational attainment in early life, mid-life hypertension, mid-life obesity, hearing loss, traumatic brain injury, excessive alcohol consumption, smoking, depression, physical inactivity, social isolation, diabetes mellitus, and air pollution. There is growing evidence that gastrointestinal tract microbiota may significantly contribute to dementia pathogenesis. In particular, gut dysbiosis can trigger metabolic diseases and the progression of low-grade systemic inflammation, being involved in much of the major modifiable risk factors. In this review, we focus on studies that have evaluated the association between modifiable risk factors for dementia and the role of gut microbiota. We also suggest clinical implications for researchers in dementia-gut microbiota related fields.
  • Altres:

    Autor segons l'article: Cabrera, Cristian; Vicens, Paloma; Torrente, Margarita
    Departament: Psicologia
    Autor/s de la URV: Cabrera Marchante, Cristian / Torrente Torné, Margarita / Vicens Calderón, Paloma
    Paraules clau: Traumatic brain-injury Risk factors Risk factor Prevention. Lifestyle Inflammation Humans Gut microbiota Gastrointestinal microbiome Dysbiosis Dementia risk factor prevention parkinsons-disease lifestyle hearing-loss gut microbiota gastrointestinal microbiome frontotemporal dementia dysbiosis cigarette-smoking body-mass index bacterial translocation alzheimers-disease air-pollution
    Resum: :Dementia is a syndrome resulting from chronic or progressive brain disease. Around 40% of worldwide dementia can be prevented or delayed by modifying 12 risk factors: low educational attainment in early life, mid-life hypertension, mid-life obesity, hearing loss, traumatic brain injury, excessive alcohol consumption, smoking, depression, physical inactivity, social isolation, diabetes mellitus, and air pollution. There is growing evidence that gastrointestinal tract microbiota may significantly contribute to dementia pathogenesis. In particular, gut dysbiosis can trigger metabolic diseases and the progression of low-grade systemic inflammation, being involved in much of the major modifiable risk factors. In this review, we focus on studies that have evaluated the association between modifiable risk factors for dementia and the role of gut microbiota. We also suggest clinical implications for researchers in dementia-gut microbiota related fields.
    Àrees temàtiques: Saúde coletiva Psicología Neurosciences Neurology (clinical) Neurology Medicine (all) Medicina iii Medicina ii Medicina i Interdisciplinar General medicine Farmacia Ensino Engenharias iv Educação física Clinical neurology Ciências biológicas ii Ciências biológicas i Ciências ambientais
    Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
    Adreça de correu electrònic de l'autor: paloma.vicens@urv.cat cristian.cabrera@estudiants.urv.cat margarita.torrente@urv.cat
    Identificador de l'autor: 0000-0003-0732-5070 0000-0002-8901-6345
    Data d'alta del registre: 2024-10-12
    Versió de l'article dipositat: info:eu-repo/semantics/acceptedVersion
    Enllaç font original: https://www.eurekaselect.com/article/119443
    URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
    Referència a l'article segons font original: Current Alzheimer Research. 18 (13): 993-1009
    Referència de l'ítem segons les normes APA: Cabrera, Cristian; Vicens, Paloma; Torrente, Margarita (2021). Modifiable Risk Factors for Dementia: The Role of Gut Microbiota. Current Alzheimer Research, 18(13), 993-1009. DOI: 10.2174/1567205018666211215152411
    DOI de l'article: 10.2174/1567205018666211215152411
    Entitat: Universitat Rovira i Virgili
    Any de publicació de la revista: 2021
    Tipus de publicació: Journal Publications
  • Paraules clau:

    Clinical Neurology,Neurology,Neurology (Clinical),Neurosciences
    Traumatic brain-injury
    Risk factors
    Risk factor
    Prevention.
    Lifestyle
    Inflammation
    Humans
    Gut microbiota
    Gastrointestinal microbiome
    Dysbiosis
    Dementia
    risk factor
    prevention
    parkinsons-disease
    lifestyle
    hearing-loss
    gut microbiota
    gastrointestinal microbiome
    frontotemporal dementia
    dysbiosis
    cigarette-smoking
    body-mass index
    bacterial translocation
    alzheimers-disease
    air-pollution
    Saúde coletiva
    Psicología
    Neurosciences
    Neurology (clinical)
    Neurology
    Medicine (all)
    Medicina iii
    Medicina ii
    Medicina i
    Interdisciplinar
    General medicine
    Farmacia
    Ensino
    Engenharias iv
    Educação física
    Clinical neurology
    Ciências biológicas ii
    Ciências biológicas i
    Ciências ambientais
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