Autor segons l'article: Pedrol, Eric; Garcia-Algar, Manuel; Massons, Jaume; Nazarenus, Moritz; Guerrini, Luca; Martinez, Javier; Rodenas, Airan; Fernandez-Carrascal, Ana; Aguilo, Magdalena; Estevez, Laura G; Calvo, Isabel; Olano-Daza, Ana; Garcia-Rico, Eduardo; Diaz, Francesc; Alvarez-Puebla, Ramon A
Departament: Química Física i Inorgànica
Autor/s de la URV: Aguiló Díaz, Magdalena / Alvarez Puebla, Ramon Angel / Díaz González, Francisco Manuel / Guerrini, Luca / Masons Bosch, Jaime / RODENAS SEGUI, AIRAN
Paraules clau: Samples Neoplastic cells, circulating Neoplasm metastasis Middle aged Microfluidics Microfluidic analytical techniques Magnetic resonance imaging Level Lab-on-a-chip devices Kinase inhibitor Humans Her2 Fluorescent antibody technique Female Expression Està en blanc Embedded microchips Egfr Disease progression Cell line, tumor Case-control studies Capture Breast neoplasms Biomarkers, tumor Biomarkers Aged Adult
Resum: Metastatic cancer patients require a continuous monitoring during the sequential treatment cycles to carefully evaluate their disease evolution. Repetition of biopsies is very invasive and not always feasible. Herein, we design and demonstrate a 3D-flow focusing microfluidic device, where all optics are integrated into the chip, for the fluorescence quantification of CTCs in real samples. To test the chip performance, two cell membrane targets, the epithelial cell adhesion molecule, EpCAM, and the receptor tyrosine-protein kinase, HER2, are selected. The efficiency of the platform
Àrees temàtiques: Zootecnia / recursos pesqueiros Saúde coletiva Química Psicología Odontología Nutrição Multidisciplinary sciences Multidisciplinary Medicina veterinaria Medicina iii Medicina ii Medicina i Materiais Matemática / probabilidade e estatística Letras / linguística Interdisciplinar Geografía Geociências Farmacia Engenharias iv Engenharias iii Engenharias ii Enfermagem Educação física Educação Economia Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Ciência da computação Biotecnología Biodiversidade Astronomia / física
Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
Adreça de correu electrònic de l'autor: ramon.alvarez@urv.cat luca.guerrini@urv.cat magdalena.aguilo@urv.cat jaume.masons@urv.cat f.diaz@urv.cat
Identificador de l'autor: 0000-0003-4770-5756 0000-0002-2925-1562 0000-0001-6130-9579 0000-0003-4325-6084 0000-0003-4581-4967
Data d'alta del registre: 2025-02-19
Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
Referència a l'article segons font original: Scientific Reports. 7 (1): 3677-
Referència de l'ítem segons les normes APA: Pedrol, Eric; Garcia-Algar, Manuel; Massons, Jaume; Nazarenus, Moritz; Guerrini, Luca; Martinez, Javier; Rodenas, Airan; Fernandez-Carrascal, Ana; Agu (2017). Optofluidic device for the quantification of circulating tumor cells in breast cancer. Scientific Reports, 7(1), 3677-. DOI: 10.1038/s41598-017-04033-9
Entitat: Universitat Rovira i Virgili
Any de publicació de la revista: 2017
Tipus de publicació: Journal Publications
Repositori URV