Autor segons l'article: Iglesias-Vázquez L; Serrat N; Bedmar C; Pallejà-Millán M; Arija V
Departament: Ciències Mèdiques Bàsiques
Autor/s de la URV: Arija Val, Maria Victoria / Bedmar Carretero, Cristina / Iglesias Vazquez, Lucia
Paraules clau: Supplementation Prenatal care Pregnancy planning Neural-tube defects Keywords: Folic acid Folate Eclipses study women vitamin-b-12 deficiencies survival supplementation prenatal care pregnancy planning population infant health folate eclipses study diet determinants brain-development
Resum: This research evaluates the prevalence of inadequate folate status in early pregnancy, the pattern of prenatal folic acid (FA) supplementation and associated factors in Spanish pregnant women from the ECLIPSES study, which included 791 participants prior gestational week 12. A cross-sectional evaluation of red blood cell (RBC) folate levels was performed at recruitment and used to calculate the prevalence of folate deficiency (RBC folate<340 nmol/L) and insufficiency (RBC folate<906 nmol/L). Sociodemographic and lifestyle data, as well as information on prenatal FA supplementation were recorded. Descriptive and multivariate statistical analyses were performed. The prevalence of folate deficiency and insufficiency were 9.6% and 86.5%, respectively. Most of women used prenatal FA supplements but only 6.3% did so as recommended. Supplementation with FA during the periconceptional period abolished folate deficiency and reduced folate insufficiency. Prenatal folic acid supplementation with ?1000 ?g/d in periconceptional time and pregnancy planning increased RBC folate levels. The main risk factor for folate insufficiency in early pregnancy were getting prenatal FA supplementation out of the periconceptional time (OR 3.32, 95%CI 1.02-15.36), while for folate deficiency they were young age (OR 2.02, 95%CI 1.05-3.99), and smoking (OR 2.39, 95%CI 1.30-4.37). In addition, social and ethnic differences according to folate status were also identified. As conclusion, periconceptional FA use is crucial for achieving optimal folate levels in early pregnancy. Pregnancy planning should focus on young women, smokers, those with low consumption of folate-rich foods, low socioeconomic status or from ethnic minorities. © The Authors 2021.
Àrees temàtiques: Zootecnia / recursos pesqueiros Saúde coletiva Química Odontología Nutrition and dietetics Nutrition & dietetics Nutrição Medicine (miscellaneous) Medicina veterinaria Medicina iii Medicina ii Medicina i Matemática / probabilidade e estatística Interdisciplinar General medicine Farmacia Engenharias iv Engenharias ii Educação física Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Biotecnología Biodiversidade Administração pública e de empresas, ciências contábeis e turismo
Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
Adreça de correu electrònic de l'autor: cristina.bedmar@urv.cat lucia.iglesias@urv.cat victoria.arija@urv.cat
Identificador de l'autor: 0000-0001-7131-4144 0000-0002-1758-0975
Data d'alta del registre: 2024-09-07
Versió de l'article dipositat: info:eu-repo/semantics/acceptedVersion
Enllaç font original: https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/abs/prenatal-folic-acid-supplementation-and-folate-status-in-early-pregnancy-eclipses-study/DFCFF4C62A67CFCBE968ADEA4EBC3532
URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
Referència a l'article segons font original: British Journal Of Nutrition. 128 (10): 1938-1945
Referència de l'ítem segons les normes APA: Iglesias-Vázquez L; Serrat N; Bedmar C; Pallejà-Millán M; Arija V (2022). Prenatal folic acid supplementation and folate status in early pregnancy: ECLIPSES study. British Journal Of Nutrition, 128(10), 1938-1945. DOI: 10.1017/s0007114521004840
DOI de l'article: 10.1017/s0007114521004840
Entitat: Universitat Rovira i Virgili
Any de publicació de la revista: 2022
Tipus de publicació: Journal Publications