Autor segons l'article: Álvarez?uría A; Escribano P; Parra?blanco V; Cano?lira JF; Stchigel AM; Oarbeascoa G; Muñoz P; Guinea J
Departament: Ciències Mèdiques Bàsiques
Autor/s de la URV: Cano Lira, José Francisco / Stchigel Glikman, Alberto Miguel
Paraules clau: Neutropenia Molecular identification Invasive fungal infection Diagnosis Cephalotrichum gorgonifer Cell transplant recipients neutropenia molecular identification invasive fungal infection epidemiology diagnosis
Resum: The etiological agents of infrequent invasive fungal infections (IFI) are difficult to identify on the species level using classic morphological examination. We describe the first case of an IFI caused by Cephalotrichum gorgonifer in a neutropenic patient with a hematological malignancy and put it on the map as a new causative agent of IFI. Case report, microbiological findings and description of the etiological agent. A 60?year?old man was diagnosed with mantle cell lymphoma. A CT scan confirmed the presence of lung infiltrates located at the right upper lobe. Histological examination of one of the nodules showed a large number of narrow septate hyphae with acute?angle branching and irregular round cell morphology; vessels walls appeared infiltrated, proving an angioinvasive pulmonary IFI. Sample culture resulted positive and molecular identification proved the presence of Cephalotrichum gorgonifer. Voriconazole was used for 12 months and the patient did not report any complications or side effects. Complete remission of lymphoma was achieved later by the time chemotherapy, radiotherapy, and radioimmunotherapy consolidation were completed. We recommend the inclusion of Cephalotrichum gorgonifer in the list of opportunistic pathogens causing mycoses in neutropenic hematological patients with suspected mould?related IFI. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.
Àrees temàtiques: Plant science Mycology Microbiology (medical) Microbiology Farmacia Ecology, evolution, behavior and systematics Ciências biológicas iii Ciências biológicas ii
Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
Adreça de correu electrònic de l'autor: albertomiguel.stchigel@urv.cat jose.cano@urv.cat
Identificador de l'autor: 0000-0003-3987-7996 0000-0003-4495-4394
Data d'alta del registre: 2024-07-27
Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
Enllaç font original: https://www.mdpi.com/2309-608X/7/12/1089
URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
Referència a l'article segons font original: J Fungi (Basel). 7 (12):
Referència de l'ítem segons les normes APA: Álvarez?uría A; Escribano P; Parra?blanco V; Cano?lira JF; Stchigel AM; Oarbeascoa G; Muñoz P; Guinea J (2021). First report of an invasive infection by cephalotrichum gorgonifer in a neutropenic patient with hematological malignancy under chemotherapy. J Fungi (Basel), 7(12), -. DOI: 10.3390/jof7121089
DOI de l'article: 10.3390/jof7121089
Entitat: Universitat Rovira i Virgili
Any de publicació de la revista: 2021
Tipus de publicació: Journal Publications