Autor segons l'article: Wendel-Garcia PD; Mas A; González-Isern C; Ferrer R; Máñez R; Masclans JR; Sandoval E; Vera P; Trenado J; Fernández R; Sirvent JM; Martínez M; Ibarz M; Garro P; Lopera JL; Bodí M; Yébenes-Reyes JC; Triginer C; Vallverdú I; Baró A; Bodí F; Saludes P; Valencia M; Roche-Campo F; Huerta A; Cambra FJ; Barberà C; Echevarria J; Peñuelas Ó; Mancebo J; Ferrer R; Roca O; Nuvials X; Ruiz JC; Papiol E; Máñez R; Gumicio VD; Sandoval E; Muñoz G; Toapanta D; Castro P; Osorio J; Masclans JR; Muñoz-Bermúdez R; Parrilla F; Pérez-Teran P; Marin-Corral J; Mas A; Cancio B; Hernández-Marín S; Koborzan MR; Briones CA; Trenado J; Fernández R; Sirvent JM; Sebastian P; Saiz X; Martínez M; Ibarz M; Garro P; Pedrós C; Vendrell E; Lopera JL; Bodí M; Rodríguez A; Moreno G; Yébenes-Reves JC; Triginer C; Vallverdú I; Baró A; Morales M; Bodí F; Saludes P; Cervelló JR; Valencia M; Roche-Campo F; Franch-Llasat D; Huerta A; Santigosa P; Cambra FJ; Benito S; Barberà C; Echevarría J; Mancebo J; Vera P; Santos JA; Baldirà J; Betbesé AJ; Izura M; Morán I; Suárez JC; Zapata L; Rodríguez N; Torrens M; Cordón A; Gomila C; Flores M; Segarra A; Morales M; Mateo L; Martos M & González-Isern C
Departament: Medicina i Cirurgia
Autor/s de la URV: Bodi Saera, Maria Amparo
Paraules clau: Non-invasive oxygenation Intensive care Covid-19 Acute hypoxemic respiratory failure
Resum: Background: Non-invasive oxygenation strategies have a prominent role in the treatment of acute hypoxemic respiratory failure during the coronavirus disease 2019 (COVID-19). While the efficacy of these therapies has been studied in hospitalized patients with COVID-19, the clinical outcomes associated with oxygen masks, high-flow oxygen therapy by nasal cannula and non-invasive mechanical ventilation in critically ill intensive care unit (ICU) patients remain unclear. Methods: In this retrospective study, we used the best of nine covariate balancing algorithms on all baseline covariates in critically ill COVID-19 patients supported with > 10 L of supplemental oxygen at one of the 26 participating ICUs in Catalonia, Spain, between March 14 and April 15, 2020. Results: Of the 1093 non-invasively oxygenated patients at ICU admission treated with one of the three stand-alone non-invasive oxygenation strategies, 897 (82%) required endotracheal intubation and 310 (28%) died during the ICU stay. High-flow oxygen therapy by nasal cannula (n = 439) and non-invasive mechanical ventilation (n = 101) were associated with a lower rate of endotracheal intubation (70% and 88%, respectively) than oxygen masks (n = 553 and 91% intubated), p < 0.001. Compared to oxygen masks, high-flow oxygen therapy by nasal cannula was associated with lower ICU mortality (hazard ratio 0.75 [95% CI 0.58–0.98), and the hazard ratio for ICU mortality was 1.21 [95% CI 0.80–1.83] for non-invasive mechanical ventilation. Conclusion: In critically ill COVID-19 ICU patients and, in the absence of conclusive data, high-flow oxygen therapy by nasal cannula may be the approach of choice as the primary non-invasive oxygenation support strategy.
Àrees temàtiques: Saúde coletiva Nutrição Medicina veterinaria Medicina iii Medicina ii Medicina i Interdisciplinar Farmacia Engenharias iv Enfermagem Educação física Critical care medicine Critical care and intensive care medicine Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciência de alimentos Biotecnología
Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
Adreça de correu electrònic de l'autor: mariaamparo.bodi@urv.cat mariaamparo.bodi@urv.cat
Identificador de l'autor: 0000-0001-7652-8379 0000-0001-7652-8379
Data d'alta del registre: 2024-09-07
Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
Enllaç font original: https://ccforum.biomedcentral.com/articles/10.1186/s13054-022-03905-5
URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
Referència a l'article segons font original: Critical Care. 26 (37): 1-13
Referència de l'ítem segons les normes APA: Wendel-Garcia PD; Mas A; González-Isern C; Ferrer R; Máñez R; Masclans JR; Sandoval E; Vera P; Trenado J; Fernández R; Sirvent JM; Martínez M; Ibarz M (2022). Non-invasive oxygenation support in acutely hypoxemic COVID-19 patients admitted to the ICU: a multicenter observational retrospective study. Critical Care, 26(37), 1-13. DOI: 10.1186/s13054-022-03905-5
DOI de l'article: 10.1186/s13054-022-03905-5
Entitat: Universitat Rovira i Virgili
Any de publicació de la revista: 2022
Tipus de publicació: Journal Publications
Repositori URV