Autor segons l'article: Guo K; Alba M; Chin GP; Tong Z; Guan B; Sailor MJ; Voelcker NH; Prieto-Simón B
Departament: Enginyeria Electrònica, Elèctrica i Automàtica
Autor/s de la URV: ALBA MARTÍN, MARÍA / Prieto Simón, Beatriz
Paraules clau: acids controllable surface chemistry disorder dna dual-surface functionality electrochemical biosensor electrodes graphene layered nanostructures raman-spectroscopy surface Controllable surface chemistry Dual-surface functionality Electrochemical biosensor Layered nanostructures Porous silicon Transfer rate constants
Resum: Porous silicon (pSi) is an established porous material that offers ample opportunities for biosensor design thanks to its tunable structure, versatile surface chemistry, and large surface area. Nonetheless, its potential for electrochemical sensing is relatively unexplored. This study investigates layered carbon-stabilized pSi nanostructures with site-specific functionalities as an electrochemical biosensor. A double-layer nanostructure combining a top hydrophilic layer of thermally carbonized pSi (TCpSi) and a bottom hydrophobic layer of thermally hydrocarbonized pSi (THCpSi) is prepared. The modified layers are formed in a stepwise process, involving first an electrochemical anodization step to generate a porous layer with precisely defined pore morphological features, followed by deposition of a thin thermally carbonized coating on the pore walls via temperature-controlled acetylene decomposition. The second layer is then generated beneath the first by following the same two-step process, but the acetylene decomposition conditions are adjusted to deposit a thermally hydrocarbonized coating. The double-layer platform features excellent electrochemical properties such as fast electron-transfer kinetics, which underpin the performance of a TCpSi-THCpSi voltammetric DNA sensor. The biosensor targets a 28-nucleotide single-stranded DNA sequence with a detection limit of 0.4 pM, two orders of magnitude lower than the values reported to date by any other pSi-based electrochemical DNA sensor.
Àrees temàtiques: Arquitetura, urbanismo e design Astronomia / física Biodiversidade Biotecnología Ciências agrárias i Ciências ambientais Ciências biológicas i Ciências biológicas ii Ciências biológicas iii Economia Engenharias ii Engenharias iii Engenharias iv Farmacia General materials science Interdisciplinar Materiais Materials science (all) Materials science (miscellaneous) Materials science, multidisciplinary Medicina i Medicina ii Medicina veterinaria Medicine (miscellaneous) Nanoscience & nanotechnology Nanoscience and nanotechnology Química
Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
Adreça de correu electrònic de l'autor: beatriz.prieto-simon@urv.cat
Identificador de l'autor: 0000-0001-8016-1565
Data d'alta del registre: 2023-02-19
Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
Enllaç font original: https://pubs.acs.org/doi/10.1021/acsami.2c02113
Referència a l'article segons font original: Acs Applied Materials & Interfaces. 14 (13): 15565-15575
Referència de l'ítem segons les normes APA: Guo K; Alba M; Chin GP; Tong Z; Guan B; Sailor MJ; Voelcker NH; Prieto-Simón B (2022). Designing Electrochemical Biosensing Platforms Using Layered Carbon-Stabilized Porous Silicon Nanostructures. Acs Applied Materials & Interfaces, 14(13), 15565-15575. DOI: 10.1021/acsami.2c02113
URL Document de llicència: http://repositori.urv.cat/ca/proteccio-de-dades/
DOI de l'article: 10.1021/acsami.2c02113
Entitat: Universitat Rovira i Virgili
Any de publicació de la revista: 2022
Tipus de publicació: Journal Publications
Repositori URV