Autor según el artículo: Guo K; Alba M; Chin GP; Tong Z; Guan B; Sailor MJ; Voelcker NH; Prieto-Simón B
Departamento: Enginyeria Electrònica, Elèctrica i Automàtica
Autor/es de la URV: ALBA MARTÍN, MARÍA / Prieto Simón, Beatriz
Palabras clave: acids controllable surface chemistry disorder dna dual-surface functionality electrochemical biosensor electrodes graphene layered nanostructures raman-spectroscopy surface Controllable surface chemistry Dual-surface functionality Electrochemical biosensor Layered nanostructures Porous silicon Transfer rate constants
Resumen: Porous silicon (pSi) is an established porous material that offers ample opportunities for biosensor design thanks to its tunable structure, versatile surface chemistry, and large surface area. Nonetheless, its potential for electrochemical sensing is relatively unexplored. This study investigates layered carbon-stabilized pSi nanostructures with site-specific functionalities as an electrochemical biosensor. A double-layer nanostructure combining a top hydrophilic layer of thermally carbonized pSi (TCpSi) and a bottom hydrophobic layer of thermally hydrocarbonized pSi (THCpSi) is prepared. The modified layers are formed in a stepwise process, involving first an electrochemical anodization step to generate a porous layer with precisely defined pore morphological features, followed by deposition of a thin thermally carbonized coating on the pore walls via temperature-controlled acetylene decomposition. The second layer is then generated beneath the first by following the same two-step process, but the acetylene decomposition conditions are adjusted to deposit a thermally hydrocarbonized coating. The double-layer platform features excellent electrochemical properties such as fast electron-transfer kinetics, which underpin the performance of a TCpSi-THCpSi voltammetric DNA sensor. The biosensor targets a 28-nucleotide single-stranded DNA sequence with a detection limit of 0.4 pM, two orders of magnitude lower than the values reported to date by any other pSi-based electrochemical DNA sensor.
Áreas temáticas: Arquitetura, urbanismo e design Astronomia / física Biodiversidade Biotecnología Ciências agrárias i Ciências ambientais Ciências biológicas i Ciências biológicas ii Ciências biológicas iii Economia Engenharias ii Engenharias iii Engenharias iv Farmacia General materials science Interdisciplinar Materiais Materials science (all) Materials science (miscellaneous) Materials science, multidisciplinary Medicina i Medicina ii Medicina veterinaria Medicine (miscellaneous) Nanoscience & nanotechnology Nanoscience and nanotechnology Química
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
Direcció de correo del autor: beatriz.prieto-simon@urv.cat
Identificador del autor: 0000-0001-8016-1565
Fecha de alta del registro: 2023-02-19
Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
Enlace a la fuente original: https://pubs.acs.org/doi/10.1021/acsami.2c02113
Referencia al articulo segun fuente origial: Acs Applied Materials & Interfaces. 14 (13): 15565-15575
Referencia de l'ítem segons les normes APA: Guo K; Alba M; Chin GP; Tong Z; Guan B; Sailor MJ; Voelcker NH; Prieto-Simón B (2022). Designing Electrochemical Biosensing Platforms Using Layered Carbon-Stabilized Porous Silicon Nanostructures. Acs Applied Materials & Interfaces, 14(13), 15565-15575. DOI: 10.1021/acsami.2c02113
URL Documento de licencia: http://repositori.urv.cat/ca/proteccio-de-dades/
DOI del artículo: 10.1021/acsami.2c02113
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2022
Tipo de publicación: Journal Publications
Repositori URV