Autor segons l'article: Konieczna, Jadwiga; Fiol, Miguel; Colom, Antoni; Angel Martinez-Gonzalez, Miguel; Salas-Salvado, Jordi; Corella, Dolores; Trinidad Soria-Florido, Maria; Alfredo Martinez, J.; Alonso-Gomez, Angel M.; Warnberg, Julia; Vioque, Jesus; Lopez-Miranda, Jose; Estruch, Ramon; Rosa Bernal-Lopez, M.; Lapetra, Jose; Serra-Majem, Lluis; Bueno-Cavanillas, Aurora; Tur, Josep A.; Martin Sanchez, Vicente; Pinto, Xavier; Gaforio, Jose J.; Matia-Martin, Pilar; Vidal, Josep; Vazquez, Clotilde; Daimiel, Lidia; Ros, Emilio; Bes-Rastrollo, Maira; Pascual, Maria; Sorli, Jose, V; Goday, Albert; Angeles Zulet, Maria; Moreno-Rodriguez, Anai; Carmona Gonzalez, Francisco Jesus; Valls-Enguix, Rafael; Janer, Juana M.; Garcia-Rios, Antonio; Casas, Rosa; Gomez-Perez, Ana M.; Manuel Santos-Lozano, Jose; Javier Basterra-Gortari, F.; Angeles Martinez, Maria; Ortega-Azorin, Carolina; Bayo, Joan; Abete, Itziar; Salaverria-Lete, Itziar; Ruiz-Canela, Miguel; Babio, Nancy; Carres, Lourdes; Romaguera, Dora;
Departament: Bioquímica i Biotecnologia
Autor/s de la URV: Babio Sánchez, Nancy Elvira / Martínez Rodríguez, María Ángeles / Salas Salvadó, Jorge
Paraules clau: Validation Ultra-processed foods Risk Questionnaire Physical-activity Nutrition Metabolic syndrome Mediterranean diet adherence Load Liver health markers Hepatic steatosis index Glycemic index Fatty liver index Disease
Resum: Non-alcoholic fatty liver disease (NAFLD) includes a spectrum of liver alterations that can result in severe disease and even death. Consumption of ultra-processed foods (UPF) has been associated with obesity and related comorbidities. However, the link between UPF and NAFLD has not been sufficiently assessed. We aimed to investigate the prospective association between UPF consumption and liver health biomarkers. Methods: We followed for 1 year 5867 older participants with overweight/obesity and metabolic syndrome (MetS) from the PREDIMED-Plus trial. A validated 143-item semi-quantitative food frequency questionnaire was used to evaluate consumption of UPF at baseline, 6, and 12 months. The degree of processing for foods and beverages (g/day) was established according to the NOVA classification system. The non-invasive fatty liver index (FLI) and hepatic steatosis index (HSI) were used to evaluate liver health at three points in time. The associations between changes in UPF consumption (percentage of total daily dietary intake (g)) and liver biomarkers were assessed using mixed-effects linear models with repeated measurements. Results: In this cohort, UPF consumption at baseline was 8.19% (SD 6.95%) of total daily dietary intake in grams. In multivariable models, each 10% daily increment in UPF consumption in 1 year was associated with significantly greater FLI (beta 1.60 points, 95% CI 1.24;1.96 points) and HSI (0.43, 0.29; 0.57) scores (all p-values < 0.001). These associations persisted statistically significant after adjusting for potential dietary confounders and NAFLD risk factors. Conclusions: A higher UPF consumption was associated with higher levels of NAFLD-related biomarkers in older adults with overweight/obesity and MetS.
Àrees temàtiques: Zootecnia / recursos pesqueiros Saúde coletiva Química Psicología Planejamento urbano e regional / demografia Nutrition and dietetics Nutrition & dietetics Nutrição Medicina veterinaria Medicina iii Medicina ii Medicina i Interdisciplinar Food science Farmacia Engenharias iv Engenharias ii Enfermagem Educação física Economia Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Biotecnología
Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
Adreça de correu electrònic de l'autor: mangeles.martinez@urv.cat jordi.salas@urv.cat nancy.babio@urv.cat
Identificador de l'autor: 0000-0001-8595-3772 0000-0003-2700-7459 0000-0003-3527-5277
Data d'alta del registre: 2024-09-07
Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
Enllaç font original: https://www.mdpi.com/2072-6643/14/19/4142
URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
Referència a l'article segons font original: Nutrients. 14 (19):
Referència de l'ítem segons les normes APA: Konieczna, Jadwiga; Fiol, Miguel; Colom, Antoni; Angel Martinez-Gonzalez, Miguel; Salas-Salvado, Jordi; Corella, Dolores; Trinidad Soria-Florido, Mari (2022). Does Consumption of Ultra-Processed Foods Matter for Liver Health? Prospective Analysis among Older Adults with Metabolic Syndrome. Nutrients, 14(19), -. DOI: 10.3390/nu14194142
DOI de l'article: 10.3390/nu14194142
Entitat: Universitat Rovira i Virgili
Any de publicació de la revista: 2022
Tipus de publicació: Journal Publications