Articles producció científica> Ciències Mèdiques Bàsiques

The 2022 Assisi Think Tank Meeting: White paper on optimising radiation therapy for breast cancer

  • Dades identificatives

    Identificador: imarina:9320453
    Autors:
    Aristei CKaidar-Person OBoersma LLeonardi MCOffersen BFranco PArenas MBourgier CPfeffer RKouloulias VBölükbaşı YMeattini IColes CLuis AMMasiello VPalumbo IMorganti AGPerrucci ETombolini VKrengli MMarazzi FTrigo LBorghesi SCiabattoni ARatoša IValentini VPoortmans P
    Resum:
    The present white paper, referring to the 4th Assisi Think Tank Meeting on breast cancer, reviews state-of-the-art data, on-going studies and research proposals. < 70% agreement in an online questionnaire identified the following clinical challenges: 1: Nodal RT in patients who have a) 1-2 positive sentinel nodes without ALND (axillary lymph node dissection); b) cN1 disease transformed into ypN0 by primary systemic therapy and c) 1-3 positive nodes after mastectomy and ALND. 2. The optimal combination of RT and immunotherapy (IT), patient selection, IT-RT timing, and RT optimal dose, fractionation and target volume. Most experts agreed that RT- IT combination does not enhance toxicity. 3: Re-irradiation for local relapse converged on the use of partial breast irradiation after second breast conserving surgery. Hyperthermia aroused support but is not widely available. Further studies are required to finetune best practice, especially given the increasing use of re-irradiation.Copyright © 2023. Published by Elsevier B.V.
  • Altres:

    Autor segons l'article: Aristei C; Kaidar-Person O; Boersma L; Leonardi MC; Offersen B; Franco P; Arenas M; Bourgier C; Pfeffer R; Kouloulias V; Bölükbaşı Y; Meattini I; Coles C; Luis AM; Masiello V; Palumbo I; Morganti AG; Perrucci E; Tombolini V; Krengli M; Marazzi F; Trigo L; Borghesi S; Ciabattoni A; Ratoša I; Valentini V; Poortmans P
    Departament: Ciències Mèdiques Bàsiques
    Autor/s de la URV: Arenas Prat, Meritxell
    Paraules clau: Re-irradiation in relapsed patients Radiation therapy Immunotherapy Combined modality treatment Breast cancer
    Resum: The present white paper, referring to the 4th Assisi Think Tank Meeting on breast cancer, reviews state-of-the-art data, on-going studies and research proposals. < 70% agreement in an online questionnaire identified the following clinical challenges: 1: Nodal RT in patients who have a) 1-2 positive sentinel nodes without ALND (axillary lymph node dissection); b) cN1 disease transformed into ypN0 by primary systemic therapy and c) 1-3 positive nodes after mastectomy and ALND. 2. The optimal combination of RT and immunotherapy (IT), patient selection, IT-RT timing, and RT optimal dose, fractionation and target volume. Most experts agreed that RT- IT combination does not enhance toxicity. 3: Re-irradiation for local relapse converged on the use of partial breast irradiation after second breast conserving surgery. Hyperthermia aroused support but is not widely available. Further studies are required to finetune best practice, especially given the increasing use of re-irradiation.Copyright © 2023. Published by Elsevier B.V.
    Àrees temàtiques: Saúde coletiva Oncology Odontología Medicina ii Medicina i Hematology Geriatrics and gerontology Ciências biológicas i Biotecnología
    Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
    Adreça de correu electrònic de l'autor: meritxell.arenas@urv.cat
    Identificador de l'autor: 0000-0003-0815-2570
    Data d'alta del registre: 2024-08-03
    Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
    Enllaç font original: https://www.sciencedirect.com/science/article/pii/S1040842823001233?via%3Dihub
    URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
    Referència a l'article segons font original: Critical Reviews In Oncology Hematology. 187 104035-104035
    Referència de l'ítem segons les normes APA: Aristei C; Kaidar-Person O; Boersma L; Leonardi MC; Offersen B; Franco P; Arenas M; Bourgier C; Pfeffer R; Kouloulias V; Bölükbaşı Y; Meattini I; Cole (2023). The 2022 Assisi Think Tank Meeting: White paper on optimising radiation therapy for breast cancer. Critical Reviews In Oncology Hematology, 187(), 104035-104035. DOI: 10.1016/j.critrevonc.2023.104035
    DOI de l'article: 10.1016/j.critrevonc.2023.104035
    Entitat: Universitat Rovira i Virgili
    Any de publicació de la revista: 2023
    Tipus de publicació: Journal Publications
  • Paraules clau:

    Geriatrics and Gerontology,Hematology,Oncology
    Re-irradiation in relapsed patients
    Radiation therapy
    Immunotherapy
    Combined modality treatment
    Breast cancer
    Saúde coletiva
    Oncology
    Odontología
    Medicina ii
    Medicina i
    Hematology
    Geriatrics and gerontology
    Ciências biológicas i
    Biotecnología
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