Autor segons l'article: Hernandez, V; Hansen, CR; Widesott, L; Bäck, A; Canters, R; Fusella, M; Götstedt, J; Jurado-Bruggeman, D; Mukumoto, N; Kaplan, LP; Koniarová, I; Piotrowski, T; Placidi, L; Vaniqui, A; Jornet, N
Departament: Ciències Mèdiques Bàsiques
Autor/s de la URV: Hernandez Masgrau, Victor
Paraules clau: Aperture complexity Complexity Complexity metrics Dose metrics Head Imrt Index Margins Modulated proton therapy Normal tissue Plan quality Radiation-therapy Range uncertainties Robust evaluation Robust optimisation Robustness Treatment uncertainties
Resum: Plan evaluation is a key step in the radiotherapy treatment workflow. Central to this step is the assessment of treatment plan quality. Hence, it is important to agree on what we mean by plan quality and to be fully aware of which parameters it depends on. We understand plan quality in radiotherapy as the clinical suitability of the delivered dose distribution that can be realistically expected from a treatment plan. Plan quality is commonly assessed by evaluating the dose distribution calculated by the treatment planning system (TPS). Evaluating the 3D dose distribution is not easy, however; it is hard to fully evaluate its spatial characteristics and we still lack the knowledge for personalising the prediction of the clinical outcome based on individual patient characteristics. This advocates for standardisation and systematic collection of clinical data and outcomes after radiotherapy. Additionally, the calculated dose distribution is not exactly the dose delivered to the patient due to uncertainties in the dose calculation and the treatment delivery, including variations in the patient set-up and anatomy. Consequently, plan quality also depends on the robustness and complexity of the treatment plan. We believe that future work and consensus on the best metrics for quality indices are required. Better tools are needed in TPSs for the evaluation of dose distributions, for the robust evaluation and optimisation of treatment plans, and for controlling and reporting plan complexity. Implementation of such tools and a better understanding of these concepts will facilitate the handling of these characteristics in clinical practice and be helpful to increase the overall quality of treatment plans in radiotherapy. (C) 2020 The Authors. Published by Elsevier B.V.
Àrees temàtiques: Astronomia / física Ciências biológicas i Ciências biológicas ii Engenharias ii Engenharias iv General medicine Hematology Interdisciplinar Medicina i Medicina ii Odontología Oncology Radiology, nuclear medicine & medical imaging Radiology, nuclear medicine and imaging Saúde coletiva
Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
Adreça de correu electrònic de l'autor: victor.hernandez@urv.cat
Identificador de l'autor: 0000-0003-3770-8486
Data d'alta del registre: 2024-01-16
Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
Enllaç font original: https://www.thegreenjournal.com/article/S0167-8140(20)30813-6/fulltext
Referència a l'article segons font original: Radiotherapy And Oncology. 153 26-33
Referència de l'ítem segons les normes APA: Hernandez, V; Hansen, CR; Widesott, L; Bäck, A; Canters, R; Fusella, M; Götstedt, J; Jurado-Bruggeman, D; Mukumoto, N; Kaplan, LP; Koniarová, I; Piotr (2020). What is plan quality in radiotherapy? The importance of evaluating dose metrics, complexity, and robustness of treatment plans. Radiotherapy And Oncology, 153(), 26-33. DOI: 10.1016/j.radonc.2020.09.038
URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
DOI de l'article: 10.1016/j.radonc.2020.09.038
Entitat: Universitat Rovira i Virgili
Any de publicació de la revista: 2020
Tipus de publicació: Journal Publications
Repositori URV