Autor segons l'article: Marcé-Nogué, J; Liu, J
Departament: Enginyeria Mecànica
Autor/s de la URV: Marcé Nogué, Jordi
Paraules clau: Zebrafish Weberian apparatus Sound conduction Ostariophysi Ossicles Ontogeny Morphology Inner-ear Human middle-ear Homology Hearing Finite element method Auditory-sensitivity Adult
Resum: Zebrafish, an essential vertebrate model, has greatly expanded our understanding of hearing. However, one area that remains unexplored is the biomechanics of the Weberian apparatus, crucial for sound conduction and perception. Using micro-computed tomography (mu CT) bioimaging, we created three-dimensional finite element models of the zebrafish Weberian ossicles. These models ranged from the exact size to scaled isometric versions with constrained geometry (1 to 10 mm in ossicular chain length). Harmonic finite element analysis of all 11 models revealed that the resonance frequency of the zebrafish's Weberian ossicular chain is approximately 900 Hz, matching their optimal hearing range. Interestingly, resonance frequency negatively correlated with size, while the ratio of peak displacement and difference of resonance frequency between tripus and scaphium remained constant. This suggests the transmission efficiency of the ossicular chain and the homogeneity of resonance frequency at both ends of the chain are not size-dependent. We conclude that the Weberian apparatus's resonance frequency can explain zebrafish's best hearing frequency, and their biomechanical characteristics are not influenced by isometric ontogeny. As the first biomechanical modelling of atympanic ear and among the few non-human ear modelling, this study provides a methodological framework for further investigations into hearing mechanisms and the hearing evolution of vertebrates.
Àrees temàtiques: Saúde coletiva Psychology Pedagogical & educational research Multidisciplinary sciences Medicina ii Matemática / probabilidade e estatística Interdisciplinary research in the social sciences Interdisciplinary research in the humanities Interdisciplinar Engenharias iii Educação física Educação Cultural studies Ciencias sociales Ciencias humanas Ciências biológicas ii Ciências biológicas i Ciências agrárias i Biotechnology Biophysics Biomedical engineering Biomaterials Bioengineering Biodiversidade Biochemistry Astronomia / física Anthropology
Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
Adreça de correu electrònic de l'autor: jordi.marce@urv.cat
Identificador de l'autor: 0000-0001-9852-7027
Data d'alta del registre: 2024-08-03
Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
Enllaç font original: https://royalsocietypublishing.org/doi/10.1098/rsif.2023.0553
URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
Referència a l'article segons font original: Journal Of The Royal Society Interface. 21 (210): 20230553-
Referència de l'ítem segons les normes APA: Marcé-Nogué, J; Liu, J (2024). Finite element modelling of sound transmission in the Weberian apparatus of zebrafish (Danio rerio). Journal Of The Royal Society Interface, 21(210), 20230553-. DOI: 10.1098/rsif.2023.0553
DOI de l'article: 10.1098/rsif.2023.0553
Entitat: Universitat Rovira i Virgili
Any de publicació de la revista: 2024
Tipus de publicació: Journal Publications