Autor segons l'article: de Cuevillas, Begona; Riezu-Boj, Jose I; Milagro, Fermin I; Alquegui, Sergio Galera; Babio, Nancy; Pastor-Villaescusa, Belen; Gil-Campos, Mercedes; Leis, Rosaura; De Miguel-Etayo, Pilar; Moreno, Luis A; Salas-Salvado, Jordi; Martinez, J Alfredo; Navas-Carretero, Santiago
Departament: Bioquímica i Biotecnologia
Autor/s de la URV: Babio Sánchez, Nancy Elvira / Salas Salvadó, Jorge
Paraules clau: Rna, ribosomal, 16s; Prevotella; Plasma; Pediatric obesity; Parents; Offspring; Microbiota; Male; Logistic models; Lifestyle factors; Lifestyle factor; Humans; Gut; Glucose; Genetics; Gastrointestinal microbiome; Female; Feces; Die; Desulfovibrio; Childhood obesity; Child; Body weight; Bacteria; Adult
Resum: Objectives: Childhood obesity continues to rise worldwide. Family gut microorganisms may be associated with childhood obesity. The aim of the study was to analyze bacterial similarities in fecal microbiota composition between parent-offspring pairs as linked to body weight. Methods: A total of 146 father/mother and offspring pairs were categorized into four groups according to the weight status of the parent-child pair as follows: group 1, parent and child with normal weight; group 2, parent and child with overweight/obesity; group 3, parent with normal weight and child with overweight/ obesity; group 4, parent with overweight/obesity and child with normal weight. Anthropometric measurements and lifestyle assessments were performed in all participants. Microbiota characteristics were determined by 16S ribosomal RNA gene sequencing. Logistic regression models were performed to determine whether the abundance of any bacteria was able to predict childhood obesity. Moreover, receiver operating characteristic curves were fitted to define the relative diagnostic strength of bacterial taxa for the correct identification of childhood obesity. Results: The absence/abundance of Catenibacterium mitsuokai, Prevotella stercorea, Desulfovibrio piger, Massiliprevotella massiliensis, and Phascolarctobacterium succinatutens was involved in body weight family associations. A positive relationship between P. succinatutens richness from parents and M. massiliensis from children was observed with regard to body weight status (odds ratio, 1.14, P = 0.013). Conclusions: This study describes five potential gut bacteria that may be putatively involved in family weight status relationships and appear to be useful for predicting obesity. (c) 2024 The Author(s). Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
Àrees temàtiques: Serviço social; Saúde coletiva; Química; Psicología; Odontología; Nutrition and dietetics; Nutrition & dietetics; Nutrição; Medicina veterinaria; Medicina iii; Medicina ii; Medicina i; Matemática / probabilidade e estatística; Interdisciplinar; General medicine; Farmacia; Engenharias iii; Engenharias ii; Enfermagem; Endocrinology, diabetes and metabolism; Educação física; Educação; Ciências biológicas iii; Ciências biológicas ii; Ciências biológicas i; Ciências ambientais; Ciências agrárias i; Ciência de alimentos; Biotecnología; Biodiversidade; Astronomia / física; Arquitetura, urbanismo e design
Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
Adreça de correu electrònic de l'autor: jordi.salas@urv.cat; nancy.babio@urv.cat
Data d'alta del registre: 2025-02-19
Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
Enllaç font original: https://www.sciencedirect.com/science/article/pii/S0899900724002521
Referència a l'article segons font original: Nutrition. 130 112603-
Referència de l'ítem segons les normes APA: de Cuevillas, Begona; Riezu-Boj, Jose I; Milagro, Fermin I; Alquegui, Sergio Galera; Babio, Nancy; Pastor-Villaescusa, Belen; Gil-Campos, Mercedes; Le (2025). Parent-child microbiota relationships involved in childhood obesity: A CORALS ancillary study. Nutrition, 130(), 112603-. DOI: 10.1016/j.nut.2024.112603
URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
DOI de l'article: 10.1016/j.nut.2024.112603
Entitat: Universitat Rovira i Virgili
Any de publicació de la revista: 2025
Tipus de publicació: Journal Publications
Repositori URV