Articles producció científica> Bioquímica i Biotecnologia

TNF, a key role in obesity?

  • Identification data

    Identifier: PC:1629
    Authors:
    M Bullo BonetP Garcia LordaFJ Lopez SorianoJM ArgilésJ Salas Salvado
    Abstract:
    Tumour necrosis factor-K (TNF) is a pleiotropic cytokine involved in many metabolic responses in both normal and pathophysiological states. In spite of the fact that this cytokine (also known as "cachectin") has been related to many of the metabolic abnormalities associated with cachexia, recent studies suggest that TNF may also have a central role in obesity modulating energy expenditure, fat deposition and insulin resistance. This review deals with the role of TNF in the control of fat mass and obesity.
  • Others:

    Author, as appears in the article.: M Bullo Bonet; P Garcia Lorda; FJ Lopez Soriano; JM Argilés; J Salas Salvado
    Department: Bioquímica i Biotecnologia
    URV's Author/s: BULLÓ BONET, MÒNICA; P Garcia Lorda; FJ Lopez Soriano; JM Argilés; SALAS SALVADÓ, JORGE
    Keywords: TNF obesity Insulin resistance
    Abstract: Tumour necrosis factor-K (TNF) is a pleiotropic cytokine involved in many metabolic responses in both normal and pathophysiological states. In spite of the fact that this cytokine (also known as "cachectin") has been related to many of the metabolic abnormalities associated with cachexia, recent studies suggest that TNF may also have a central role in obesity modulating energy expenditure, fat deposition and insulin resistance. This review deals with the role of TNF in the control of fat mass and obesity.
    Research group: Alimentació, Nutrició, Creixement i Salut Mental
    Thematic Areas: Bioquímica i biotecnologia Bioquímica y tecnología Biochemistry and technology
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 0014-5793
    Author identifier: orcid.org/0000-0002-0218-7046; orcid.org/0000-0001-8938-7229; N/D; N/D; orcid.org/0000-0003-2700-7459
    Record's date: 2016-06-08
    Last page: 219
    Journal volume: 451
    Papper version: info:eu-repo/semantics/publishedVersion
    Link to the original source: https://www.sciencedirect.com/science/article/pii/S0014579399005402
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Article's DOI: 10.1016/S0014-5793(99)00540-2
    Entity: Universitat Rovira i Virgili
    Journal publication year: 1999
    First page: 215
    Publication Type: Article Artículo Article
  • Keywords:

    Insulinoresistència
    Factor de necrosi tumoral
    Obesitat
    TNF
    obesity
    Insulin resistance
    Bioquímica i biotecnologia
    Bioquímica y tecnología
    Biochemistry and technology
    0014-5793
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