Articles producció científica> Bioquímica i Biotecnologia

CAIcal: A combined set of tools to assess codon usage adaptation

  • Identification data

    Identifier: imarina:2083890
    Authors:
    Puigbo, PereBravo, Ignacio G.Garcia-Vallve, Santiago
    Abstract:
    The Codon Adaptation Index (CAI) was first developed to measure the synonymous codon usage bias for a DNA or RNA sequence. The CAI quantifies the similarity between the synonymous codon usage of a gene and the synonymous codon frequency of a reference set.We describe here CAIcal, a web-server available at http://genomes.urv.es/CAIcal that includes a complete set of utilities related with the CAI. The server provides useful important features, such as the calculation and graphical representation of the CAI along either an individual sequence or a protein multiple sequence alignment translated to DNA. The automated calculation of CAI and its expected value is also included as one of the CAIcal tools. The software is also free to be downloaded as a stand alone application for local use.The CAIcal server provides a complete set of tools to assess codon usage adaptation and to help in genome annotation.
  • Others:

    Author, as appears in the article.: Puigbo, Pere; Bravo, Ignacio G.; Garcia-Vallve, Santiago;
    Department: Bioquímica i Biotecnologia
    URV's Author/s: Garcia Vallve, Santiago / PUIGBÒ AVALOS, PEDRO
    Keywords: Server Prokaryotic complete genomes Papillomavirus genomes Metabolism Index Highly expressed genes Db Database Cycle Bias
    Abstract: The Codon Adaptation Index (CAI) was first developed to measure the synonymous codon usage bias for a DNA or RNA sequence. The CAI quantifies the similarity between the synonymous codon usage of a gene and the synonymous codon frequency of a reference set.We describe here CAIcal, a web-server available at http://genomes.urv.es/CAIcal that includes a complete set of utilities related with the CAI. The server provides useful important features, such as the calculation and graphical representation of the CAI along either an individual sequence or a protein multiple sequence alignment translated to DNA. The automated calculation of CAI and its expected value is also included as one of the CAIcal tools. The software is also free to be downloaded as a stand alone application for local use.The CAIcal server provides a complete set of tools to assess codon usage adaptation and to help in genome annotation.
    Thematic Areas: Modeling and simulation Medicina ii Medicina i Matemática / probabilidade e estatística Immunology General biochemistry,genetics and molecular biology General agricultural and biological sciences Ecology, evolution, behavior and systematics Ciências biológicas ii Ciências biológicas i Ciência da computação Biotecnología Biology Biodiversidade Biochemistry, genetics and molecular biology (miscellaneous) Biochemistry, genetics and molecular biology (all) Astronomia / física Applied mathematics Agricultural and biological sciences (miscellaneous) Agricultural and biological sciences (all)
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 17456150
    Author's mail: santi.garcia-vallve@urv.cat
    Author identifier: 0000-0002-0348-7497
    Record's date: 2023-02-18
    Papper version: info:eu-repo/semantics/publishedVersion
    Link to the original source: https://biologydirect.biomedcentral.com/articles/10.1186/1745-6150-3-38
    Papper original source: Biology Direct. 3 (38): 38-
    APA: Puigbo, Pere; Bravo, Ignacio G.; Garcia-Vallve, Santiago; (2008). CAIcal: A combined set of tools to assess codon usage adaptation. Biology Direct, 3(38), 38-. DOI: 10.1186/1745-6150-3-38
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Article's DOI: 10.1186/1745-6150-3-38
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2008
    Publication Type: Journal Publications
  • Keywords:

    Agricultural and Biological Sciences (Miscellaneous),Applied Mathematics,Biochemistry, Genetics and Molecular Biology (Miscellaneous),Biology,Ecology, Evolution, Behavior and Systematics,Immunology,Modeling and Simulation
    Server
    Prokaryotic complete genomes
    Papillomavirus genomes
    Metabolism
    Index
    Highly expressed genes
    Db
    Database
    Cycle
    Bias
    Modeling and simulation
    Medicina ii
    Medicina i
    Matemática / probabilidade e estatística
    Immunology
    General biochemistry,genetics and molecular biology
    General agricultural and biological sciences
    Ecology, evolution, behavior and systematics
    Ciências biológicas ii
    Ciências biológicas i
    Ciência da computação
    Biotecnología
    Biology
    Biodiversidade
    Biochemistry, genetics and molecular biology (miscellaneous)
    Biochemistry, genetics and molecular biology (all)
    Astronomia / física
    Applied mathematics
    Agricultural and biological sciences (miscellaneous)
    Agricultural and biological sciences (all)
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