Articles producció científica> Química Analítica i Química Orgànica

Paper-based enzymatic electrode with enhanced potentiometric response for monitoring glucose in biological fluids

  • Identification data

    Identifier: imarina:5130501
    Authors:
    Parrilla M, Cánovas R, Andrade FJ
    Abstract:
    A novel paper-based potentiometric sensor with an enhanced response for the detection of glucose in biological fluids is presented. The electrode consists on platinum sputtered on a filter paper and a Nafion membrane to immobilize the enzyme glucose oxidase. The response obtained is proportional to the logarithm of the concentration of glucose, with a sensitivity of ¿119±8 mV·decade¿1, a linear range that spans from 10¿4M to 10¿2.5 M and a limit of detection of 10¿4.5 M of glucose. It is shown that Nafion increases the sensitivity of the technique while minimizing interferences. Validation with human serum samples shows an excellent agreement when compared to standard methods. This approach can become an interesting alternative for the development of simple and affordable devices for point of care and home-based diagnostics.
  • Others:

    Author, as appears in the article.: Parrilla M, Cánovas R, Andrade FJ
    Department: Química Analítica i Química Orgànica
    URV's Author/s: Andrade, Francisco Javier
    Keywords: Potentiometry Paper-based sensor Nafion Glucose Enzymatic sensors paper-based sensor nafion glucose enzymatic sensors
    Abstract: A novel paper-based potentiometric sensor with an enhanced response for the detection of glucose in biological fluids is presented. The electrode consists on platinum sputtered on a filter paper and a Nafion membrane to immobilize the enzyme glucose oxidase. The response obtained is proportional to the logarithm of the concentration of glucose, with a sensitivity of ¿119±8 mV·decade¿1, a linear range that spans from 10¿4M to 10¿2.5 M and a limit of detection of 10¿4.5 M of glucose. It is shown that Nafion increases the sensitivity of the technique while minimizing interferences. Validation with human serum samples shows an excellent agreement when compared to standard methods. This approach can become an interesting alternative for the development of simple and affordable devices for point of care and home-based diagnostics.
    Thematic Areas: Química Nanoscience and nanotechnology Nanoscience & nanotechnology Medicine (miscellaneous) Medicina ii Medicina i Materiais Interdisciplinar Farmacia Engenharias iv Engenharias iii Engenharias ii Electrochemistry Economia Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Chemistry, analytical Biotecnología Biotechnology & applied microbiology Biotechnology Biophysics Biomedical engineering Biodiversidade Astronomia / física
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 0956-5663
    Author's mail: franciscojavier.andrade@urv.cat
    Author identifier: 0000-0003-1199-2837
    Record's date: 2024-09-07
    Papper version: info:eu-repo/semantics/submittedVersion
    Link to the original source: https://www.sciencedirect.com/science/article/abs/pii/S0956566316311745?via%3Dihub
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Papper original source: Biosensors & Bioelectronics. 90 110-116
    APA: Parrilla M, Cánovas R, Andrade FJ (2017). Paper-based enzymatic electrode with enhanced potentiometric response for monitoring glucose in biological fluids. Biosensors & Bioelectronics, 90(), 110-116. DOI: 10.1016/j.bios.2016.11.034
    Article's DOI: 10.1016/j.bios.2016.11.034
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2017
    Publication Type: Journal Publications
  • Keywords:

    Biomedical Engineering,Biophysics,Biotechnology,Biotechnology & Applied Microbiology,Chemistry, Analytical,Electrochemistry,Medicine (Miscellaneous),Nanoscience & Nanotechnology,Nanoscience and Nanotechnology
    Potentiometry
    Paper-based sensor
    Nafion
    Glucose
    Enzymatic sensors
    paper-based sensor
    nafion
    glucose
    enzymatic sensors
    Química
    Nanoscience and nanotechnology
    Nanoscience & nanotechnology
    Medicine (miscellaneous)
    Medicina ii
    Medicina i
    Materiais
    Interdisciplinar
    Farmacia
    Engenharias iv
    Engenharias iii
    Engenharias ii
    Electrochemistry
    Economia
    Ciências biológicas iii
    Ciências biológicas ii
    Ciências biológicas i
    Ciências ambientais
    Ciências agrárias i
    Chemistry, analytical
    Biotecnología
    Biotechnology & applied microbiology
    Biotechnology
    Biophysics
    Biomedical engineering
    Biodiversidade
    Astronomia / física
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