Author, as appears in the article.: Parrilla M, Cánovas R, Andrade FJ

Department: Química Analítica i Química Orgànica

URV's Author/s: Andrade, Francisco Javier

Keywords: Potentiometry Paper-based sensor Nafion Glucose Enzymatic sensors paper-based sensor nafion glucose enzymatic sensors

Abstract: A novel paper-based potentiometric sensor with an enhanced response for the detection of glucose in biological fluids is presented. The electrode consists on platinum sputtered on a filter paper and a Nafion membrane to immobilize the enzyme glucose oxidase. The response obtained is proportional to the logarithm of the concentration of glucose, with a sensitivity of ¿119±8 mV·decade¿1, a linear range that spans from 10¿4M to 10¿2.5 M and a limit of detection of 10¿4.5 M of glucose. It is shown that Nafion increases the sensitivity of the technique while minimizing interferences. Validation with human serum samples shows an excellent agreement when compared to standard methods. This approach can become an interesting alternative for the development of simple and affordable devices for point of care and home-based diagnostics.

Thematic Areas: Química Nanoscience and nanotechnology Nanoscience & nanotechnology Medicine (miscellaneous) Medicina ii Medicina i Materiais Interdisciplinar Farmacia Engenharias iv Engenharias iii Engenharias ii Electrochemistry Economia Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Chemistry, analytical Biotecnología Biotechnology & applied microbiology Biotechnology Biophysics Biomedical engineering Biodiversidade Astronomia / física

licence for use: https://creativecommons.org/licenses/by/3.0/es/

ISSN: 0956-5663

Author's mail: franciscojavier.andrade@urv.cat

Author identifier: 0000-0003-1199-2837

Record's date: 2023-02-18

Papper version: info:eu-repo/semantics/submittedVersion

Link to the original source: https://www.sciencedirect.com/science/article/abs/pii/S0956566316311745?via%3Dihub

Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/

Papper original source: Biosensors & Bioelectronics. 90 110-116

APA: Parrilla M, Cánovas R, Andrade FJ (2017). Paper-based enzymatic electrode with enhanced potentiometric response for monitoring glucose in biological fluids. Biosensors & Bioelectronics, 90(), 110-116. DOI: 10.1016/j.bios.2016.11.034

Article's DOI: 10.1016/j.bios.2016.11.034

Entity: Universitat Rovira i Virgili

Journal publication year: 2017

Publication Type: Journal Publications