Articles producció científica> Química Analítica i Química Orgànica

Paper-based enzymatic electrode with enhanced potentiometric response for monitoring glucose in biological fluids

  • Datos identificativos

    Identificador: imarina:5130501
    Autores:
    Parrilla M, Cánovas R, Andrade FJ
    Resumen:
    A novel paper-based potentiometric sensor with an enhanced response for the detection of glucose in biological fluids is presented. The electrode consists on platinum sputtered on a filter paper and a Nafion membrane to immobilize the enzyme glucose oxidase. The response obtained is proportional to the logarithm of the concentration of glucose, with a sensitivity of ¿119±8 mV·decade¿1, a linear range that spans from 10¿4M to 10¿2.5 M and a limit of detection of 10¿4.5 M of glucose. It is shown that Nafion increases the sensitivity of the technique while minimizing interferences. Validation with human serum samples shows an excellent agreement when compared to standard methods. This approach can become an interesting alternative for the development of simple and affordable devices for point of care and home-based diagnostics.
  • Otros:

    Autor según el artículo: Parrilla M, Cánovas R, Andrade FJ
    Departamento: Química Analítica i Química Orgànica
    Autor/es de la URV: Andrade, Francisco Javier
    Palabras clave: Potentiometry Paper-based sensor Nafion Glucose Enzymatic sensors paper-based sensor nafion glucose enzymatic sensors
    Resumen: A novel paper-based potentiometric sensor with an enhanced response for the detection of glucose in biological fluids is presented. The electrode consists on platinum sputtered on a filter paper and a Nafion membrane to immobilize the enzyme glucose oxidase. The response obtained is proportional to the logarithm of the concentration of glucose, with a sensitivity of ¿119±8 mV·decade¿1, a linear range that spans from 10¿4M to 10¿2.5 M and a limit of detection of 10¿4.5 M of glucose. It is shown that Nafion increases the sensitivity of the technique while minimizing interferences. Validation with human serum samples shows an excellent agreement when compared to standard methods. This approach can become an interesting alternative for the development of simple and affordable devices for point of care and home-based diagnostics.
    Áreas temáticas: Química Nanoscience and nanotechnology Nanoscience & nanotechnology Medicine (miscellaneous) Medicina ii Medicina i Materiais Interdisciplinar Farmacia Engenharias iv Engenharias iii Engenharias ii Electrochemistry Economia Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Chemistry, analytical Biotecnología Biotechnology & applied microbiology Biotechnology Biophysics Biomedical engineering Biodiversidade Astronomia / física
    Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 0956-5663
    Direcció de correo del autor: franciscojavier.andrade@urv.cat
    Identificador del autor: 0000-0003-1199-2837
    Fecha de alta del registro: 2024-09-07
    Versión del articulo depositado: info:eu-repo/semantics/submittedVersion
    Enlace a la fuente original: https://www.sciencedirect.com/science/article/abs/pii/S0956566316311745?via%3Dihub
    URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
    Referencia al articulo segun fuente origial: Biosensors & Bioelectronics. 90 110-116
    Referencia de l'ítem segons les normes APA: Parrilla M, Cánovas R, Andrade FJ (2017). Paper-based enzymatic electrode with enhanced potentiometric response for monitoring glucose in biological fluids. Biosensors & Bioelectronics, 90(), 110-116. DOI: 10.1016/j.bios.2016.11.034
    DOI del artículo: 10.1016/j.bios.2016.11.034
    Entidad: Universitat Rovira i Virgili
    Año de publicación de la revista: 2017
    Tipo de publicación: Journal Publications
  • Palabras clave:

    Biomedical Engineering,Biophysics,Biotechnology,Biotechnology & Applied Microbiology,Chemistry, Analytical,Electrochemistry,Medicine (Miscellaneous),Nanoscience & Nanotechnology,Nanoscience and Nanotechnology
    Potentiometry
    Paper-based sensor
    Nafion
    Glucose
    Enzymatic sensors
    paper-based sensor
    nafion
    glucose
    enzymatic sensors
    Química
    Nanoscience and nanotechnology
    Nanoscience & nanotechnology
    Medicine (miscellaneous)
    Medicina ii
    Medicina i
    Materiais
    Interdisciplinar
    Farmacia
    Engenharias iv
    Engenharias iii
    Engenharias ii
    Electrochemistry
    Economia
    Ciências biológicas iii
    Ciências biológicas ii
    Ciências biológicas i
    Ciências ambientais
    Ciências agrárias i
    Chemistry, analytical
    Biotecnología
    Biotechnology & applied microbiology
    Biotechnology
    Biophysics
    Biomedical engineering
    Biodiversidade
    Astronomia / física
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