Autor según el artículo: Parrilla M, Cánovas R, Andrade FJ

Departamento: Química Analítica i Química Orgànica

Autor/es de la URV: Andrade, Francisco Javier

Palabras clave: Potentiometry Paper-based sensor Nafion Glucose Enzymatic sensors paper-based sensor nafion glucose enzymatic sensors

Resumen: A novel paper-based potentiometric sensor with an enhanced response for the detection of glucose in biological fluids is presented. The electrode consists on platinum sputtered on a filter paper and a Nafion membrane to immobilize the enzyme glucose oxidase. The response obtained is proportional to the logarithm of the concentration of glucose, with a sensitivity of ¿119±8 mV·decade¿1, a linear range that spans from 10¿4M to 10¿2.5 M and a limit of detection of 10¿4.5 M of glucose. It is shown that Nafion increases the sensitivity of the technique while minimizing interferences. Validation with human serum samples shows an excellent agreement when compared to standard methods. This approach can become an interesting alternative for the development of simple and affordable devices for point of care and home-based diagnostics.

Áreas temáticas: Química Nanoscience and nanotechnology Nanoscience & nanotechnology Medicine (miscellaneous) Medicina ii Medicina i Materiais Interdisciplinar Farmacia Engenharias iv Engenharias iii Engenharias ii Electrochemistry Economia Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Chemistry, analytical Biotecnología Biotechnology & applied microbiology Biotechnology Biophysics Biomedical engineering Biodiversidade Astronomia / física

Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/

ISSN: 0956-5663

Direcció de correo del autor: franciscojavier.andrade@urv.cat

Identificador del autor: 0000-0003-1199-2837

Fecha de alta del registro: 2023-02-18

Versión del articulo depositado: info:eu-repo/semantics/submittedVersion

Enlace a la fuente original: https://www.sciencedirect.com/science/article/abs/pii/S0956566316311745?via%3Dihub

URL Documento de licencia: http://repositori.urv.cat/ca/proteccio-de-dades/

Referencia al articulo segun fuente origial: Biosensors & Bioelectronics. 90 110-116

Referencia de l'ítem segons les normes APA: Parrilla M, Cánovas R, Andrade FJ (2017). Paper-based enzymatic electrode with enhanced potentiometric response for monitoring glucose in biological fluids. Biosensors & Bioelectronics, 90(), 110-116. DOI: 10.1016/j.bios.2016.11.034

DOI del artículo: 10.1016/j.bios.2016.11.034

Entidad: Universitat Rovira i Virgili

Año de publicación de la revista: 2017

Tipo de publicación: Journal Publications