Articles producció científicaMedicina i Cirurgia

Gut Microbiota-Derived Mediators as Potential Markers in Nonalcoholic Fatty Liver Disease

  • Identification data

    Identifier:  imarina:5132827
    Handle: https://hdl.handle.net/20.500.11797/imarina5132827
    Authors:  Aragones, Gemma; Gonzalez-Garcia, Sergio; Aguilar, Carmen; Richart, Cristobal; Auguet, Teresa
    Abstract:
    Nonalcoholic fatty liver disease (NAFLD) is a common, multifactorial, and poorly understood liver disease whose incidence is globally rising. During the past decade, several lines of evidence suggest that dysbiosis of intestinal microbiome represents an important factor contributing to NAFLD occurrence and its progression into NASH. The mechanisms that associate dysbiosis with NAFLD include changes in microbiota-derived mediators, deregulation of the gut endothelial barrier, translocation of mediators of dysbiosis, and hepatic inflammation. Changes in short chain fatty acids, bile acids, bacterial components, choline, and ethanol are the result of altered intestinal microbiota. We perform a narrative review of the previously published evidence and discuss the use of gut microbiota-derived mediators as potential markers in NAFLD.

  • Others:

    Link to the original source: https://www.hindawi.com/journals/bmri/2019/8507583/
    APA: Aragones, Gemma; Gonzalez-Garcia, Sergio; Aguilar, Carmen; Richart, Cristobal; Auguet, Teresa (2019). Gut Microbiota-Derived Mediators as Potential Markers in Nonalcoholic Fatty Liver Disease. Biomed Research International, 2019(), 8507583-. DOI: 10.1155/2019/8507583
    Paper original source: Biomed Research International. 2019 8507583-
    Article's DOI: 10.1155/2019/8507583
    Journal publication year: 2019
    Entity: Universitat Rovira i Virgili
    Paper version: info:eu-repo/semantics/publishedVersion
    Record's date: 2025-03-03
    URV's Author/s: Aguilar Crespillo, Carmen Isabel / ARAGONÈS BARGALLÓ, GEMMA / Auguet Quintillà, Maria Teresa / Richart Jurado, Cristobal Manuel
    Department: Medicina i Cirurgia
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Publication Type: Journal Publications
    ISSN: 23146133
    Author, as appears in the article.: Aragones, Gemma; Gonzalez-Garcia, Sergio; Aguilar, Carmen; Richart, Cristobal; Auguet, Teresa
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    Thematic Areas: Zootecnia / recursos pesqueiros, Saúde coletiva, Química, Psicología, Odontología, Nutrição, Medicine, research & experimental, Medicine (miscellaneous), Medicina veterinaria, Medicina iii, Medicina ii, Medicina i, Materiais, Matemática / probabilidade e estatística, Interdisciplinar, Immunology and microbiology (miscellaneous), Immunology and microbiology (all), Geografía, General immunology and microbiology, General biochemistry,genetics and molecular biology, Farmacia, Ensino, Engenharias iv, Engenharias iii, Engenharias ii, Engenharias i, Enfermagem, Educação física, Economia, Ciências biológicas iii, Ciências biológicas ii, Ciências biológicas i, Ciências ambientais, Ciências agrárias i, Ciência de alimentos, Ciência da computação, Biotecnología, Biotechnology & applied microbiology, Biodiversidade, Biochemistry, genetics and molecular biology (miscellaneous), Biochemistry, genetics and molecular biology (all), Astronomia / física, Antropologia / arqueologia
    Author's mail: cristobalmanuel.richart@urv.cat, carmenisabel.aguilar@urv.cat, carmenisabel.aguilar@urv.cat, mariateresa.auguet@urv.cat

  • Keywords:

    Trimethylamine-n-oxide
    Tnf-alpha
    Steatohepatitis
    Receptor
    Plasma-levels
    Obese-patients
    Non-alcoholic fatty liver disease
    Increased intestinal permeability
    Humans
    Gastrointestinal microbiome
    Fatty acids
    volatile
    Biomarkers
    Bile-acids induce
    Bile acids and salts
    Animals
    Alpha gene
    Activation
    Biochemistry
    Genetics and Molecular Biology (Miscellaneous)
    Biotechnology & Applied Microbiology
    Immunology and Microbiology (Miscellaneous)
    Medicine (Miscellaneous)
    Medicine
    Research & Experimental
    Zootecnia / recursos pesqueiros
    Saúde coletiva
    Química
    Psicología
    Odontología
    Nutrição
    Medicina veterinaria
    Medicina iii
    Medicina ii
    Medicina i
    Materiais
    Matemática / probabilidade e estatística
    Interdisciplinar
    Immunology and microbiology (all)
    Geografía
    General immunology and microbiology
    General biochemistry
    genetics and molecular biology
    Farmacia
    Ensino
    Engenharias iv
    Engenharias iii
    Engenharias ii
    Engenharias i
    Enfermagem
    Educação física
    Economia
    Ciências biológicas iii
    Ciências biológicas ii
    Ciências biológicas i
    Ciências ambientais
    Ciências agrárias i
    Ciência de alimentos
    Ciência da computação
    Biotecnología
    Biodiversidade
    genetics and molecular biology (all)
    Astronomia / física
    Antropologia / arqueologia

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