Articles producció científica> Medicina i Cirurgia

Cost-effectiveness of early detection of breast cancer in Catalonia (Spain)

  • Identification data

    Identifier: imarina:6386622
    Authors:
    Carles MVilaprinyo ECots FGregori APla RRomán RSala MMacià FCastells XRue M
    Abstract:
    Background: Breast cancer (BC) causes more deaths than any other cancer among women in Catalonia. Early detection has contributed to the observed decline in BC mortality. However, there is debate on the optimal screening strategy. We performed an economic evaluation of 20 screening strategies taking into account the cost over time of screening and subsequent medical costs, including diagnostic confirmation, initial treatment, follow-up and advanced care.Methods: We used a probabilistic model to estimate the effect and costs over time of each scenario. The effect was measured as years of life (YL), quality-adjusted life years (QALY), and lives extended (LE). Costs of screening and treatment were obtained from the Early Detection Program and hospital databases of the IMAS-Hospital del Mar in Barcelona. The incremental cost-effectiveness ratio (ICER) was used to compare the relative costs and outcomes of different scenarios.Results: Strategies that start at ages 40 or 45 and end at 69 predominate when the effect is measured as YL or QALYs. Biennial strategies 50-69, 45-69 or annual 45-69, 40-69 and 40-74 were selected as cost-effective for both effect measures (YL or QALYs). The ICER increases considerably when moving from biennial to annual scenarios. Moving from no screening to biennial 50-69 years represented an ICER of 4,469€ per QALY.Conclusions: A reduced number of screening strategies have been selected for consideration by researchers, decision makers and policy planners. Mathematical models are useful to assess the impact and costs of BC screening in a specific geographical area. © 2011 Carles et al; licensee BioMed Central Ltd.
  • Others:

    Author, as appears in the article.: Carles M; Vilaprinyo E; Cots F; Gregori A; Pla R; Román R; Sala M; Macià F; Castells X; Rue M
    Department: Economia Medicina i Cirurgia
    URV's Author/s: Carles Lavila, Misericòrdia / GREGORI GOMIS, ALEIX / Pla Farnòs, Roger Jesús
    Keywords: Us Stage Spain Screening Quality-adjusted life years Patterns Mortality Models, statistical Middle aged Mammography Life expectancy Humans Female Economic-evaluation Early detection of cancer Disease Cost-benefit analysis Cáncer de mama Breast neoplasms Avaluació econòmica de tecnologies sanitàries Aged, 80 and over Aged Age Adult
    Abstract: Background: Breast cancer (BC) causes more deaths than any other cancer among women in Catalonia. Early detection has contributed to the observed decline in BC mortality. However, there is debate on the optimal screening strategy. We performed an economic evaluation of 20 screening strategies taking into account the cost over time of screening and subsequent medical costs, including diagnostic confirmation, initial treatment, follow-up and advanced care.Methods: We used a probabilistic model to estimate the effect and costs over time of each scenario. The effect was measured as years of life (YL), quality-adjusted life years (QALY), and lives extended (LE). Costs of screening and treatment were obtained from the Early Detection Program and hospital databases of the IMAS-Hospital del Mar in Barcelona. The incremental cost-effectiveness ratio (ICER) was used to compare the relative costs and outcomes of different scenarios.Results: Strategies that start at ages 40 or 45 and end at 69 predominate when the effect is measured as YL or QALYs. Biennial strategies 50-69, 45-69 or annual 45-69, 40-69 and 40-74 were selected as cost-effective for both effect measures (YL or QALYs). The ICER increases considerably when moving from biennial to annual scenarios. Moving from no screening to biennial 50-69 years represented an ICER of 4,469€ per QALY.Conclusions: A reduced number of screening strategies have been selected for consideration by researchers, decision makers and policy planners. Mathematical models are useful to assess the impact and costs of BC screening in a specific geographical area. © 2011 Carles et al; licensee BioMed Central Ltd.
    Thematic Areas: Saúde coletiva Química Planejamento urbano e regional / demografia Oncology Odontología Nutrição Medicina veterinaria Medicina iii Medicina ii Medicina i Interdisciplinar Genetics Farmacia Ensino Engenharias iii Engenharias ii Educação física Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciência de alimentos Ciência da computação Cancer research Biotecnología Biodiversidade Administração, ciências contábeis e turismo
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 14712407
    Author's mail: rogerjesus.pla@urv.cat misericordia.carles@urv.cat
    Author identifier: 0000-0002-3727-8933 0000-0003-3796-3014
    Record's date: 2024-06-22
    Papper version: info:eu-repo/semantics/publishedVersion
    Link to the original source: https://bmccancer.biomedcentral.com/articles/10.1186/1471-2407-11-192
    Papper original source: Bmc Cancer. 11 192-
    APA: Carles M; Vilaprinyo E; Cots F; Gregori A; Pla R; Román R; Sala M; Macià F; Castells X; Rue M (2011). Cost-effectiveness of early detection of breast cancer in Catalonia (Spain). Bmc Cancer, 11(), 192-. DOI: 10.1186/1471-2407-11-192
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Article's DOI: 10.1186/1471-2407-11-192
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2011
    Publication Type: Journal Publications
  • Keywords:

    Cancer Research,Genetics,Oncology
    Us
    Stage
    Spain
    Screening
    Quality-adjusted life years
    Patterns
    Mortality
    Models, statistical
    Middle aged
    Mammography
    Life expectancy
    Humans
    Female
    Economic-evaluation
    Early detection of cancer
    Disease
    Cost-benefit analysis
    Cáncer de mama
    Breast neoplasms
    Avaluació econòmica de tecnologies sanitàries
    Aged, 80 and over
    Aged
    Age
    Adult
    Saúde coletiva
    Química
    Planejamento urbano e regional / demografia
    Oncology
    Odontología
    Nutrição
    Medicina veterinaria
    Medicina iii
    Medicina ii
    Medicina i
    Interdisciplinar
    Genetics
    Farmacia
    Ensino
    Engenharias iii
    Engenharias ii
    Educação física
    Ciências biológicas iii
    Ciências biológicas ii
    Ciências biológicas i
    Ciência de alimentos
    Ciência da computação
    Cancer research
    Biotecnología
    Biodiversidade
    Administração, ciências contábeis e turismo
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