Articles producció científica> Química Analítica i Química Orgànica

Different sample treatments for the determination of ICM-XR in fish samples followed by LC-HRMS

  • Identification data

    Identifier: imarina:6388904
    Authors:
    Nunez, MireiaBorrull, FrancescFontanals, NuriaPocurull, Eva
    Abstract:
    © 2016 Elsevier B.V. Iodinated X-ray contrast media (ICM-XR) are a group of pharmaceuticals widely used in medicine. Due to their low biodegradation rate, which makes their removal at wastewater treatment plants difficult, and the high doses at which they are administered, they have been detected in aquatic environments. In the present paper, a method for the quantitative determination of a group of ICM-XR in different fish species was developed and validated for the first time. Two extraction techniques were compared: pressurised liquid extraction (PLE) and QuEChERS (Quick, Easy, Cheap, Effective, Rugged and Safe), with PLE being selected, followed by liquid chromatography-high resolution mass spectrometry. In addition, several clean-up strategies were evaluated. The optimised method provided PLE recoveries ranging from 60% to 88% and limits of detection ranging from 5 ng/g to 25 ng/g (dry weight). The method was applied in order to evaluate the presence of the selected ICM-XR in different fish species.
  • Others:

    Author, as appears in the article.: Nunez, Mireia; Borrull, Francesc; Fontanals, Nuria; Pocurull, Eva
    Department: Química Analítica i Química Orgànica
    URV's Author/s: Borrull Ballarín, Francesc / Fontanals Torroja, Núria / NÚÑEZ MARCÉ, MIREIA / Pocurull Aixala, Eva
    Keywords: Pressurised liquid extraction Matrix effect Iodinated x-ray contrast media High resolution mass spectrometry Fish samples matrix effect iodinated x-ray contrast media high resolution mass spectrometry fish samples
    Abstract: © 2016 Elsevier B.V. Iodinated X-ray contrast media (ICM-XR) are a group of pharmaceuticals widely used in medicine. Due to their low biodegradation rate, which makes their removal at wastewater treatment plants difficult, and the high doses at which they are administered, they have been detected in aquatic environments. In the present paper, a method for the quantitative determination of a group of ICM-XR in different fish species was developed and validated for the first time. Two extraction techniques were compared: pressurised liquid extraction (PLE) and QuEChERS (Quick, Easy, Cheap, Effective, Rugged and Safe), with PLE being selected, followed by liquid chromatography-high resolution mass spectrometry. In addition, several clean-up strategies were evaluated. The optimised method provided PLE recoveries ranging from 60% to 88% and limits of detection ranging from 5 ng/g to 25 ng/g (dry weight). The method was applied in order to evaluate the presence of the selected ICM-XR in different fish species.
    Thematic Areas: Zootecnia / recursos pesqueiros Spectroscopy Saúde coletiva Química Nutrição Medicina veterinaria Medicina iii Medicina ii Medicina i Materiais Interdisciplinar Geociências General medicine General chemistry Farmacia Ensino Engenharias iv Engenharias iii Engenharias ii Engenharias i Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Chemistry, analytical Chemistry (miscellaneous) Biotecnología Biodiversidade Biochemistry Astronomia / física Analytical chemistry Administração pública e de empresas, ciências contábeis e turismo
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 00399140
    Author's mail: nuria.fontanals@urv.cat nuria.fontanals@urv.cat eva.pocurull@urv.cat francesc.borrull@urv.cat
    Author identifier: 0000-0002-7534-1964 0000-0002-7534-1964 0000-0001-5123-995X 0000-0003-2718-9336
    Record's date: 2024-10-12
    Papper version: info:eu-repo/semantics/acceptedVersion
    Link to the original source: https://www.sciencedirect.com/science/article/abs/pii/S0039914016308669
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Papper original source: Talanta. 163 1-7
    APA: Nunez, Mireia; Borrull, Francesc; Fontanals, Nuria; Pocurull, Eva (2017). Different sample treatments for the determination of ICM-XR in fish samples followed by LC-HRMS. Talanta, 163(), 1-7. DOI: 10.1016/j.talanta.2016.11.004
    Article's DOI: 10.1016/j.talanta.2016.11.004
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2017
    Publication Type: Journal Publications
  • Keywords:

    Analytical Chemistry,Biochemistry,Chemistry (Miscellaneous),Chemistry, Analytical,Spectroscopy
    Pressurised liquid extraction
    Matrix effect
    Iodinated x-ray contrast media
    High resolution mass spectrometry
    Fish samples
    matrix effect
    iodinated x-ray contrast media
    high resolution mass spectrometry
    fish samples
    Zootecnia / recursos pesqueiros
    Spectroscopy
    Saúde coletiva
    Química
    Nutrição
    Medicina veterinaria
    Medicina iii
    Medicina ii
    Medicina i
    Materiais
    Interdisciplinar
    Geociências
    General medicine
    General chemistry
    Farmacia
    Ensino
    Engenharias iv
    Engenharias iii
    Engenharias ii
    Engenharias i
    Ciências biológicas iii
    Ciências biológicas ii
    Ciências biológicas i
    Ciências ambientais
    Ciências agrárias i
    Ciência de alimentos
    Chemistry, analytical
    Chemistry (miscellaneous)
    Biotecnología
    Biodiversidade
    Biochemistry
    Astronomia / física
    Analytical chemistry
    Administração pública e de empresas, ciências contábeis e turismo
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