Author, as appears in the article.: Nunez, Mireia; Borrull, Francesc; Fontanals, Nuria; Pocurull, Eva
Department: Química Analítica i Química Orgànica
URV's Author/s: Borrull Ballarín, Francesc / Fontanals Torroja, Núria / NÚÑEZ MARCÉ, MIREIA / Pocurull Aixala, Eva
Keywords: Pressurised liquid extraction Matrix effect Iodinated x-ray contrast media High resolution mass spectrometry Fish samples matrix effect iodinated x-ray contrast media high resolution mass spectrometry fish samples
Abstract: © 2016 Elsevier B.V. Iodinated X-ray contrast media (ICM-XR) are a group of pharmaceuticals widely used in medicine. Due to their low biodegradation rate, which makes their removal at wastewater treatment plants difficult, and the high doses at which they are administered, they have been detected in aquatic environments. In the present paper, a method for the quantitative determination of a group of ICM-XR in different fish species was developed and validated for the first time. Two extraction techniques were compared: pressurised liquid extraction (PLE) and QuEChERS (Quick, Easy, Cheap, Effective, Rugged and Safe), with PLE being selected, followed by liquid chromatography-high resolution mass spectrometry. In addition, several clean-up strategies were evaluated. The optimised method provided PLE recoveries ranging from 60% to 88% and limits of detection ranging from 5 ng/g to 25 ng/g (dry weight). The method was applied in order to evaluate the presence of the selected ICM-XR in different fish species.
Thematic Areas: Zootecnia / recursos pesqueiros Spectroscopy Saúde coletiva Química Nutrição Medicina veterinaria Medicina iii Medicina ii Medicina i Materiais Interdisciplinar Geociências General medicine General chemistry Farmacia Ensino Engenharias iv Engenharias iii Engenharias ii Engenharias i Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Chemistry, analytical Chemistry (miscellaneous) Biotecnología Biodiversidade Biochemistry Astronomia / física Analytical chemistry Administração pública e de empresas, ciências contábeis e turismo
licence for use: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 00399140
Author's mail: nuria.fontanals@urv.cat nuria.fontanals@urv.cat eva.pocurull@urv.cat francesc.borrull@urv.cat
Author identifier: 0000-0002-7534-1964 0000-0002-7534-1964 0000-0001-5123-995X 0000-0003-2718-9336
Record's date: 2024-10-12
Papper version: info:eu-repo/semantics/acceptedVersion
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Talanta. 163 1-7
APA: Nunez, Mireia; Borrull, Francesc; Fontanals, Nuria; Pocurull, Eva (2017). Different sample treatments for the determination of ICM-XR in fish samples followed by LC-HRMS. Talanta, 163(), 1-7. DOI: 10.1016/j.talanta.2016.11.004
Entity: Universitat Rovira i Virgili
Journal publication year: 2017
Publication Type: Journal Publications
Repositori URV