Autor según el artículo: Núñez M; Borrull F; Fontanals N; Pocurull E

Departamento: Química Analítica i Química Orgànica

Autor/es de la URV: Borrull Ballarín, Francesc / Fontanals Torroja, Núria / NÚÑEZ MARCÉ, MIREIA / Pocurull Aixala, Eva

Palabras clave: Pressurised liquid extraction Matrix effect Iodinated x-ray contrast media High resolution mass spectrometry Fish samples matrix effect iodinated x-ray contrast media high resolution mass spectrometry fish samples

Resumen: © 2016 Elsevier B.V. Iodinated X-ray contrast media (ICM-XR) are a group of pharmaceuticals widely used in medicine. Due to their low biodegradation rate, which makes their removal at wastewater treatment plants difficult, and the high doses at which they are administered, they have been detected in aquatic environments. In the present paper, a method for the quantitative determination of a group of ICM-XR in different fish species was developed and validated for the first time. Two extraction techniques were compared: pressurised liquid extraction (PLE) and QuEChERS (Quick, Easy, Cheap, Effective, Rugged and Safe), with PLE being selected, followed by liquid chromatography-high resolution mass spectrometry. In addition, several clean-up strategies were evaluated. The optimised method provided PLE recoveries ranging from 60% to 88% and limits of detection ranging from 5 ng/g to 25 ng/g (dry weight). The method was applied in order to evaluate the presence of the selected ICM-XR in different fish species.

Áreas temáticas: Zootecnia / recursos pesqueiros Spectroscopy Saúde coletiva Química Nutrição Medicina veterinaria Medicina iii Medicina ii Medicina i Materiais Interdisciplinar Geociências General medicine General chemistry Farmacia Ensino Engenharias iv Engenharias iii Engenharias ii Engenharias i Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Chemistry, analytical Chemistry (miscellaneous) Biotecnología Biodiversidade Biochemistry Astronomia / física Analytical chemistry Administração pública e de empresas, ciências contábeis e turismo

Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/

ISSN: 00399140

Direcció de correo del autor: nuria.fontanals@urv.cat francesc.borrull@urv.cat eva.pocurull@urv.cat nuria.fontanals@urv.cat

Identificador del autor: 0000-0002-7534-1964 0000-0003-2718-9336 0000-0001-5123-995X 0000-0002-7534-1964

Fecha de alta del registro: 2023-02-26

Versión del articulo depositado: info:eu-repo/semantics/acceptedVersion

Enlace a la fuente original: https://www.sciencedirect.com/science/article/abs/pii/S0039914016308669

URL Documento de licencia: http://repositori.urv.cat/ca/proteccio-de-dades/

Referencia al articulo segun fuente origial: Talanta. 163 1-7

Referencia de l'ítem segons les normes APA: Núñez M; Borrull F; Fontanals N; Pocurull E (2017). Different sample treatments for the determination of ICM-XR in fish samples followed by LC-HRMS. Talanta, 163(), 1-7. DOI: 10.1016/j.talanta.2016.11.004

DOI del artículo: 10.1016/j.talanta.2016.11.004

Entidad: Universitat Rovira i Virgili

Año de publicación de la revista: 2017

Tipo de publicación: Journal Publications