Author, as appears in the article.: Sorli-Aguilar, Mar; Martin-Lujan, Francisco; Flores-Mateo, Gemma; Jardi-Pinana, Cristina; Aparicio-Llopis, Estefania; Basora-Gallisa, Josep; Sola-Alberich, Rosa
Department: Medicina i Cirurgia Ciències Mèdiques Bàsiques
URV's Author/s: Aparicio Llopis, Estefania / Basora Gallisa, Josep / Cabre Vila, Juan Jose / Jardí Piñana, Cristina / Martín Lujan, Francisco Manuel / Solà Alberich, Rosa Maria
Keywords: Weight-gain Waist circumference Vital capacity Tobacco smoke Tobacco Spirometry Spain Smoking-cessation Smoking Pulmonary-function Overweight Obesity, abdominal Obesity Multivariate analysis Middle aged Metabolic syndrome Male Lung function test Lung Linear models Humans Health Forced expiratory volume Female Fat distribution Cross-sectional studies Body-mass index Body mass index Biomarkers Adult Adiposity
Abstract: © 2016 The Author(s). Background: The aim of this study was to assess the association of key adiposity markers with lung function in smokers without respiratory disease in a Mediterranean population. Methods: We performed a cross-sectional study with baseline data from a representative sample of the ESPITAP study in Spain. Participants were 738 smokers (52.3% men) without respiratory disease, aged 35 to 70, selected from 12 primary health care centres. We assessed weight, height, body mass index (BMI), waist circumference (WC) and waist-to-height ratio (WHtR). The pulmonary functional parameters were forced vital capacity (FVC), forced expiratory volume in 1 s (FEV1) and FEV1/FVC ratio. Results: In this cohort of smokers, 22.2% of individuals had central obesity. FVC% was inversely associated with all anthropometric measures (BMI, WC and WHtR) in the overall population and in men; in women, only BMI was associated with FVC%. FEV1% was inversely associated to BMI and WC in the overall population, and to all anthropometric measures in men. Furthermore, both BMI and obesity were positively associated with FEV1/FVC ratio overall and when stratified by sex; this suggests a restrictive pattern explained by the altered ventilator mechanics experienced by people with obesity. Conclusion: In a Mediterranean population of smokers without respiratory symptoms, abdominal obesity, evaluated not only by BMI and WC but also WHtR, is inversely associated with lung function. Fat distribution appears more strongly related to pulmonary function parameters in men than in women. In smokers with high values for WC, WHtR and BMI, assessment of lung function is recommended. Trial registration: Current Controlled Trials NCT01194596. Registered 2 September 2010.
Thematic Areas: Saúde coletiva Respiratory system Pulmonary and respiratory medicine Nutrição Medicina iii Medicina ii Medicina i Interdisciplinar Farmacia Engenharias iv Educação física Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Biotecnología
licence for use: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 14712466
Author's mail: cristina.jardi@urv.cat juanjose.cabre@urv.cat josep.basora@urv.cat estefania.aparicio@urv.cat paco.martin@urv.cat josep.basora@urv.cat rosa.sola@urv.cat
Author identifier: 0000-0002-7946-1488 0000-0003-1082-6861 0000-0003-0542-0015 0000-0003-0359-3588 0000-0002-8359-235X
Record's date: 2025-02-08
Paper version: info:eu-repo/semantics/publishedVersion
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Paper original source: Bmc Pulmonary Medicine. 16 (1): 178-
APA: Sorli-Aguilar, Mar; Martin-Lujan, Francisco; Flores-Mateo, Gemma; Jardi-Pinana, Cristina; Aparicio-Llopis, Estefania; Basora-Gallisa, Josep; Sola-Albe (2016). Adiposity markers and lung function in smokers: A cross-sectional study in a Mediterranean population. Bmc Pulmonary Medicine, 16(1), 178-. DOI: 10.1186/s12890-016-0341-y
Entity: Universitat Rovira i Virgili
Journal publication year: 2016
Publication Type: Journal Publications
Repositori URV