Articles producció científica> Bioquímica i Biotecnologia

Phenolic compounds and biological rhythms: Who takes the lead?

  • Identification data

    Identifier: imarina:9216058
    Authors:
    Ávila-Román JSoliz-Rueda JRBravo FIAragonès GSuárez MArola-Arnal AMulero MSalvadó MJArola LTorres-Fuentes CMuguerza B
    Abstract:
    Background: Phenolic compounds are one of the most heterogeneous group of plant secondary metabolites with over 50,000 diverse molecules identified so far. Despite the low bioavailability of native forms, they have been shown to exert several beneficial effects against chronic diseases such as diabetes, cardiovascular disease, and neurodegenerative diseases. There are different factors that may affect their absorption and distribution in tissues, but the exact mechanisms remain unclear. Recently, the time of the day and the season of the year in which they are consumed have emerged as another factor that may significantly impact on their metabolism and bioactivities. Scope and approach: This review emphasizes the importance of the interaction between phenolic compounds and biological rhythms and its impact on the bioactivities of these metabolites. This may have implications for the food industry as food rich in phenolic compounds may exert different effects depending on the time of consumption. Key findings and conclusions: Phenolic compounds broad activity could be explained by their extensive transformation, including metabolization in the colon by the gut microbiota, which leads to the production of multitude of different metabolites. Biological rhythms play a significant role in this metabolism affecting their bioactivities and, at the same time, phenolic compounds may exert their effects by promoting homeostasis at a basal signalling level through interactions with the biological clock system. This is in accordance with the xenohormesis hypothesis, which explains that chemical cues synthetized by plants are able to allow animals to favourably adapt to changing environmental conditions.
  • Others:

    Author, as appears in the article.: Ávila-Román J; Soliz-Rueda JR; Bravo FI; Aragonès G; Suárez M; Arola-Arnal A; Mulero M; Salvadó MJ; Arola L; Torres-Fuentes C; Muguerza B
    Department: Bioquímica i Biotecnologia
    URV's Author/s: Aragonès Bargalló, Gerard / Arola Arnal, Anna / Arola Fernández, Lluís / Ávila Román, Francisco Javier / Bravo Vázquez, Francisca Isabel / Muguerza Marquínez, Maria Begoña / Mulero Abellán, Miguel / Salvadó Rovira, Maria Josepa / Soliz Rueda, Jorge Ricardo / Suárez Recio, Manuel / Torres Fuentes, Cristina
    Keywords: Polyphenols Phenolic compounds Metabolic syndrome Dietary proanthocyanidins modulate Chrononutrition Biological rhythms Bioactive compounds resveratrol polyphenols phenolic compounds metabolic syndrome gut microbiota food-intake expression consumption circadian clock chrononutrition bioactive compounds antioxidant
    Abstract: Background: Phenolic compounds are one of the most heterogeneous group of plant secondary metabolites with over 50,000 diverse molecules identified so far. Despite the low bioavailability of native forms, they have been shown to exert several beneficial effects against chronic diseases such as diabetes, cardiovascular disease, and neurodegenerative diseases. There are different factors that may affect their absorption and distribution in tissues, but the exact mechanisms remain unclear. Recently, the time of the day and the season of the year in which they are consumed have emerged as another factor that may significantly impact on their metabolism and bioactivities. Scope and approach: This review emphasizes the importance of the interaction between phenolic compounds and biological rhythms and its impact on the bioactivities of these metabolites. This may have implications for the food industry as food rich in phenolic compounds may exert different effects depending on the time of consumption. Key findings and conclusions: Phenolic compounds broad activity could be explained by their extensive transformation, including metabolization in the colon by the gut microbiota, which leads to the production of multitude of different metabolites. Biological rhythms play a significant role in this metabolism affecting their bioactivities and, at the same time, phenolic compounds may exert their effects by promoting homeostasis at a basal signalling level through interactions with the biological clock system. This is in accordance with the xenohormesis hypothesis, which explains that chemical cues synthetized by plants are able to allow animals to favourably adapt to changing environmental conditions.
    Thematic Areas: Zootecnia / recursos pesqueiros Nutrição Medicina veterinaria Medicina i Food science & technology Food science Farmacia Engenharias ii Ciências biológicas iii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Biotechnology
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    Author's mail: franciscaisabel.bravo@urv.cat mariajosepa.salvado@urv.cat franciscojavier.avila@urv.cat jorgericardo.solizr@urv.cat jorgericardo.solizr@urv.cat lluis.arola@estudiants.urv.cat lluis.arola@estudiants.urv.cat manuel.suarez@urv.cat miquel.mulero@urv.cat anna.arola@urv.cat gerard.aragones@urv.cat begona.muguerza@urv.cat cristina.torres@urv.cat
    Author identifier: 0000-0002-6468-3088 0000-0003-3883-3326 0000-0001-9766-8178 0000-0003-0122-8253 0000-0001-6529-1345 0000-0001-7384-8588 0000-0002-2917-6910
    Record's date: 2024-07-27
    Journal volume: 113
    Papper version: info:eu-repo/semantics/publishedVersion
    Link to the original source: https://www.sciencedirect.com/science/article/pii/S0924224421003101?via%3Dihub
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Papper original source: Trends In Food Science & Technology. 113 77-85
    APA: Ávila-Román J; Soliz-Rueda JR; Bravo FI; Aragonès G; Suárez M; Arola-Arnal A; Mulero M; Salvadó MJ; Arola L; Torres-Fuentes C; Muguerza B (2021). Phenolic compounds and biological rhythms: Who takes the lead?. Trends In Food Science & Technology, 113(), 77-85. DOI: 10.1016/j.tifs.2021.04.050
    Article's DOI: 10.1016/j.tifs.2021.04.050
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2021
    Publication Type: Journal Publications
  • Keywords:

    Biotechnology,Food Science,Food Science & Technology
    Polyphenols
    Phenolic compounds
    Metabolic syndrome
    Dietary proanthocyanidins modulate
    Chrononutrition
    Biological rhythms
    Bioactive compounds
    resveratrol
    polyphenols
    phenolic compounds
    metabolic syndrome
    gut microbiota
    food-intake
    expression
    consumption
    circadian clock
    chrononutrition
    bioactive compounds
    antioxidant
    Zootecnia / recursos pesqueiros
    Nutrição
    Medicina veterinaria
    Medicina i
    Food science & technology
    Food science
    Farmacia
    Engenharias ii
    Ciências biológicas iii
    Ciências biológicas i
    Ciências ambientais
    Ciências agrárias i
    Ciência de alimentos
    Biotechnology
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