Articles producció científica> Enginyeria Electrònica, Elèctrica i Automàtica

Perspective on Multimodal Imaging Techniques Coupling Mass Spectrometry and Vibrational Spectroscopy: Picturing the Best of Both Worlds

  • Identification data

    Identifier: imarina:9216701
    Authors:
    Alexandra Iakab, StefaniaRafols, PereCorreig-Blanchar, XavierGarcia-Altares, Maria
    Abstract:
    Studies on complex biological phenomena often combine two or more imaging techniques to collect high-quality comprehensive data directly in situ, preserving the biological context. Mass spectrometry imaging (MSI) and vibrational spectroscopy imaging (VSI) complement each other in terms of spatial resolution and molecular information. In the past decade, several combinations of such multimodal strategies arose in research fields as diverse as microbiology, cancer, and forensics, overcoming many challenges toward the unification of these techniques. Here we focus on presenting the advantages and challenges of multimodal imaging from the point of view of studying biological samples as well as giving a perspective on the upcoming trends regarding this topic. The latest efforts in the field are discussed, highlighting the purpose of the technique for clinical applications.
  • Others:

    Author, as appears in the article.: Alexandra Iakab, Stefania; Rafols, Pere; Correig-Blanchar, Xavier; Garcia-Altares, Maria;
    Department: Enginyeria Electrònica, Elèctrica i Automàtica
    URV's Author/s: Garcia-Altares Pérez, Maria / Ràfols Soler, Pere
    Keywords: Vibrational spectroscopy Sweat Spatial resolution Scattering Research fields Multi-modal imaging Molecular information Mass spectrometry imaging (msi) Mass spectrometry Maldi-tof Lipidomics Imaging techniques Images Fusion Ft-ir Confocal raman microscopy Clinical application Biological samples Biological phenomena
    Abstract: Studies on complex biological phenomena often combine two or more imaging techniques to collect high-quality comprehensive data directly in situ, preserving the biological context. Mass spectrometry imaging (MSI) and vibrational spectroscopy imaging (VSI) complement each other in terms of spatial resolution and molecular information. In the past decade, several combinations of such multimodal strategies arose in research fields as diverse as microbiology, cancer, and forensics, overcoming many challenges toward the unification of these techniques. Here we focus on presenting the advantages and challenges of multimodal imaging from the point of view of studying biological samples as well as giving a perspective on the upcoming trends regarding this topic. The latest efforts in the field are discussed, highlighting the purpose of the technique for clinical applications.
    Thematic Areas: Química Medicina ii Medicina i Materiais Interdisciplinar Geociências General medicine Farmacia Ensino Engenharias iv Engenharias iii Engenharias ii Enfermagem Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Ciência da computação Chemistry, analytical Biotecnología Biodiversidade Astronomia / física Analytical chemistry
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    Author's mail: maria.garcia-altares@urv.cat pere.rafols@urv.cat
    Author identifier: 0000-0002-9240-4058
    Record's date: 2024-07-27
    Papper version: info:eu-repo/semantics/publishedVersion
    Link to the original source: https://pubs.acs.org/doi/10.1021/acs.analchem.0c04986
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Papper original source: Analytical Chemistry. 93 (16): 6301-6310
    APA: Alexandra Iakab, Stefania; Rafols, Pere; Correig-Blanchar, Xavier; Garcia-Altares, Maria; (2021). Perspective on Multimodal Imaging Techniques Coupling Mass Spectrometry and Vibrational Spectroscopy: Picturing the Best of Both Worlds. Analytical Chemistry, 93(16), 6301-6310. DOI: 10.1021/acs.analchem.0c04986
    Article's DOI: 10.1021/acs.analchem.0c04986
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2021
    Publication Type: Journal Publications
  • Keywords:

    Analytical Chemistry,Chemistry, Analytical
    Vibrational spectroscopy
    Sweat
    Spatial resolution
    Scattering
    Research fields
    Multi-modal imaging
    Molecular information
    Mass spectrometry imaging (msi)
    Mass spectrometry
    Maldi-tof
    Lipidomics
    Imaging techniques
    Images
    Fusion
    Ft-ir
    Confocal raman microscopy
    Clinical application
    Biological samples
    Biological phenomena
    Química
    Medicina ii
    Medicina i
    Materiais
    Interdisciplinar
    Geociências
    General medicine
    Farmacia
    Ensino
    Engenharias iv
    Engenharias iii
    Engenharias ii
    Enfermagem
    Ciências biológicas iii
    Ciências biológicas ii
    Ciências biológicas i
    Ciências ambientais
    Ciências agrárias i
    Ciência de alimentos
    Ciência da computação
    Chemistry, analytical
    Biotecnología
    Biodiversidade
    Astronomia / física
    Analytical chemistry
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