Autor según el artículo: Alexandra Iakab, Stefania; Rafols, Pere; Correig-Blanchar, Xavier; Garcia-Altares, Maria;

Departamento: Enginyeria Electrònica, Elèctrica i Automàtica

Autor/es de la URV: Ràfols Soler, Pere

Palabras clave: Vibrational spectroscopy Sweat Spatial resolution Scattering Research fields Multi-modal imaging Molecular information Mass spectrometry imaging (msi) Mass spectrometry Maldi-tof Lipidomics Imaging techniques Images Fusion Ft-ir Confocal raman microscopy Clinical application Biological samples Biological phenomena

Resumen: Studies on complex biological phenomena often combine two or more imaging techniques to collect high-quality comprehensive data directly in situ, preserving the biological context. Mass spectrometry imaging (MSI) and vibrational spectroscopy imaging (VSI) complement each other in terms of spatial resolution and molecular information. In the past decade, several combinations of such multimodal strategies arose in research fields as diverse as microbiology, cancer, and forensics, overcoming many challenges toward the unification of these techniques. Here we focus on presenting the advantages and challenges of multimodal imaging from the point of view of studying biological samples as well as giving a perspective on the upcoming trends regarding this topic. The latest efforts in the field are discussed, highlighting the purpose of the technique for clinical applications.

Áreas temáticas: Química Medicina ii Medicina i Materiais Interdisciplinar Geociências General medicine Farmacia Ensino Engenharias iv Engenharias iii Engenharias ii Enfermagem Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Ciência da computação Chemistry, analytical Biotecnología Biodiversidade Astronomia / física Analytical chemistry

Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/

Direcció de correo del autor: pere.rafols@urv.cat

Identificador del autor: 0000-0002-9240-4058

Fecha de alta del registro: 2023-02-19

Versión del articulo depositado: info:eu-repo/semantics/publishedVersion

Enlace a la fuente original: https://pubs.acs.org/doi/10.1021/acs.analchem.0c04986

URL Documento de licencia: http://repositori.urv.cat/ca/proteccio-de-dades/

Referencia al articulo segun fuente origial: Analytical Chemistry. 93 (16): 6301-6310

Referencia de l'ítem segons les normes APA: Alexandra Iakab, Stefania; Rafols, Pere; Correig-Blanchar, Xavier; Garcia-Altares, Maria; (2021). Perspective on Multimodal Imaging Techniques Coupling Mass Spectrometry and Vibrational Spectroscopy: Picturing the Best of Both Worlds. Analytical Chemistry, 93(16), 6301-6310. DOI: 10.1021/acs.analchem.0c04986

DOI del artículo: 10.1021/acs.analchem.0c04986

Entidad: Universitat Rovira i Virgili

Año de publicación de la revista: 2021

Tipo de publicación: Journal Publications