Articles producció científica> Ciències Mèdiques Bàsiques

The effects of some essential and toxic metals/metalloids in COVID-19: A review

  • Identification data

    Identifier: imarina:9217199
    Authors:
    Domingo, Jose L.Marques, Montse
    Abstract:
    Thousands of studies have been conducted in order to understand in depth the characteristics of the novel coronavirus SARS-CoV-2, its infectivity and ways of transmission, and very especially everything related to the clinical and severity of the COVID-19, as well as the potential treatments. In this sense, the role that essential and toxic metals/metalloids have in the development and course of this disease is being studied. Metals/metalloids such as arsenic, cadmium, lead, mercury or vanadium, are elements with known toxic effects in mammals, while trace elements such as cobalt, copper, iron, manganese, selenium and zinc are considered essential. Given the importance of metals/metalloids in nutrition and human health, the present review was aimed at assessing the relationship between various essential and toxic metals/metalloids and the health outcomes related with the COVID-19. We are in the position to conclude that particular attention must be paid to the load/levels of essential trace elements in COVID-19 patients, mainly zinc and selenium. On the other hand, the exposure to air pollutants in general, and toxic metal/metalloids in particular, should be avoided as much as possible to reduce the possibilities of viral infections, including SARS-CoV-2.
  • Others:

    Author, as appears in the article.: Domingo, Jose L.; Marques, Montse;
    Department: Ciències Mèdiques Bàsiques
    URV's Author/s: Domingo Roig, José Luis / Marquès Bueno, Montserrat
    Keywords: Zinc sulfate Zinc deficiency Zinc blood level Zinc Virus transmission Viral-infections Vanadium Trace-elements Trace elements Trace element Toxicity Toxic effects Therapy Severe acute respiratory syndrome coronavirus 2 Selenoprotein Selenium deficiency Selenium Sars-cov-2 Rna replication Risk reduction Risk factor Risk assessment Review Respiratory tract disease Respiratory failure Pneumonia Placebo Pathology Nutritional status Nonhuman Micronutrient intake Metals, heavy Metals Metalloids Metalloid Metal Mercury Manganese Lead Iron Innate immunity Infection risk Infection prevention Immunomodulation Immunity Immune response Humoral immunity Humans Human Heavy metal Gluconate zinc Environmental exposure Drug safety Drug efficacy Disease severity Disease predisposition Disease 2019 causal Deficiencies Covid-19 patients Covid-19 Coronavirus disease 2019 Copper intake Copper deficiency Copper Cobalt Cell maturation Cd4+ t lymphocyte Cadmium Ascorbic acid Arsenic Antibody production Animals Animal Air pollution Air pollutants Air pollutant
    Abstract: Thousands of studies have been conducted in order to understand in depth the characteristics of the novel coronavirus SARS-CoV-2, its infectivity and ways of transmission, and very especially everything related to the clinical and severity of the COVID-19, as well as the potential treatments. In this sense, the role that essential and toxic metals/metalloids have in the development and course of this disease is being studied. Metals/metalloids such as arsenic, cadmium, lead, mercury or vanadium, are elements with known toxic effects in mammals, while trace elements such as cobalt, copper, iron, manganese, selenium and zinc are considered essential. Given the importance of metals/metalloids in nutrition and human health, the present review was aimed at assessing the relationship between various essential and toxic metals/metalloids and the health outcomes related with the COVID-19. We are in the position to conclude that particular attention must be paid to the load/levels of essential trace elements in COVID-19 patients, mainly zinc and selenium. On the other hand, the exposure to air pollutants in general, and toxic metal/metalloids in particular, should be avoided as much as possible to reduce the possibilities of viral infections, including SARS-CoV-2.
    Thematic Areas: Toxicology Saúde coletiva Química Odontología Nutrição Medicine (miscellaneous) Medicina veterinaria Medicina iii Medicina ii Medicina i Materiais Interdisciplinar Food science & technology Food science Farmacia Ensino Engenharias iv Engenharias ii Enfermagem Educação física Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Biotecnología Biodiversidade Astronomia / física
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    Author's mail: montserrat.marques@urv.cat joseluis.domingo@urv.cat
    Author identifier: 0000-0001-6302-8578 0000-0001-6647-9470
    Record's date: 2024-07-27
    Papper version: info:eu-repo/semantics/publishedVersion
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Papper original source: Food And Chemical Toxicology. 152 (112161):
    APA: Domingo, Jose L.; Marques, Montse; (2021). The effects of some essential and toxic metals/metalloids in COVID-19: A review. Food And Chemical Toxicology, 152(112161), -. DOI: 10.1016/j.fct.2021.112161
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2021
    Publication Type: Journal Publications
  • Keywords:

    Food Science,Food Science & Technology,Medicine (Miscellaneous),Toxicology
    Zinc sulfate
    Zinc deficiency
    Zinc blood level
    Zinc
    Virus transmission
    Viral-infections
    Vanadium
    Trace-elements
    Trace elements
    Trace element
    Toxicity
    Toxic effects
    Therapy
    Severe acute respiratory syndrome coronavirus 2
    Selenoprotein
    Selenium deficiency
    Selenium
    Sars-cov-2
    Rna replication
    Risk reduction
    Risk factor
    Risk assessment
    Review
    Respiratory tract disease
    Respiratory failure
    Pneumonia
    Placebo
    Pathology
    Nutritional status
    Nonhuman
    Micronutrient intake
    Metals, heavy
    Metals
    Metalloids
    Metalloid
    Metal
    Mercury
    Manganese
    Lead
    Iron
    Innate immunity
    Infection risk
    Infection prevention
    Immunomodulation
    Immunity
    Immune response
    Humoral immunity
    Humans
    Human
    Heavy metal
    Gluconate zinc
    Environmental exposure
    Drug safety
    Drug efficacy
    Disease severity
    Disease predisposition
    Disease 2019 causal
    Deficiencies
    Covid-19 patients
    Covid-19
    Coronavirus disease 2019
    Copper intake
    Copper deficiency
    Copper
    Cobalt
    Cell maturation
    Cd4+ t lymphocyte
    Cadmium
    Ascorbic acid
    Arsenic
    Antibody production
    Animals
    Animal
    Air pollution
    Air pollutants
    Air pollutant
    Toxicology
    Saúde coletiva
    Química
    Odontología
    Nutrição
    Medicine (miscellaneous)
    Medicina veterinaria
    Medicina iii
    Medicina ii
    Medicina i
    Materiais
    Interdisciplinar
    Food science & technology
    Food science
    Farmacia
    Ensino
    Engenharias iv
    Engenharias ii
    Enfermagem
    Educação física
    Ciências biológicas iii
    Ciências biológicas ii
    Ciências biológicas i
    Ciências ambientais
    Ciências agrárias i
    Ciência de alimentos
    Biotecnología
    Biodiversidade
    Astronomia / física
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