Author, as appears in the article.: Domingo, Jose L; Marques, Montse
Department: Ciències Mèdiques Bàsiques
URV's Author/s: Domingo Roig, José Luis / Marquès Bueno, Montserrat
Keywords: Zinc sulfate; Zinc deficiency; Zinc blood level; Zinc; Virus transmission; Viral-infections; Vanadium; Trace-elements; Trace elements; Trace element; Toxicity; Toxic effects; Therapy; Severe acute respiratory syndrome coronavirus 2; Selenoprotein; Selenium deficiency; Selenium; Sars-cov-2; Rna replication; Risk reduction; Risk factor; Risk assessment; Review; Respiratory tract disease; Respiratory failure; Pneumonia; Placebo; Pathology; Nutritional status; Nonhuman; Micronutrient intake; Metals, heavy; Metals; Metalloids; Metalloid; Metal; Mercury; Manganese; Lead; Iron; Innate immunity; Infection risk; Infection prevention; Immunomodulation; Immunity; Immune response; Humoral immunity; Humans; Human; Heavy metal; Gluconate zinc; Environmental exposure; Drug safety; Drug efficacy; Disease severity; Disease predisposition; Disease 2019 causal; Deficiencies; Covid-19 patients; Covid-19; Coronavirus disease 2019; Copper intake; Copper deficiency; Copper; Cobalt; Cell maturation; Cd4+ t lymphocyte; Cadmium; Ascorbic acid; Arsenic; Antibody production; Animals; Animal; Air pollution; Air pollutants; Air pollutant
Abstract: Thousands of studies have been conducted in order to understand in depth the characteristics of the novel coronavirus SARS-CoV-2, its infectivity and ways of transmission, and very especially everything related to the clinical and severity of the COVID-19, as well as the potential treatments. In this sense, the role that essential and toxic metals/metalloids have in the development and course of this disease is being studied. Metals/metalloids such as arsenic, cadmium, lead, mercury or vanadium, are elements with known toxic effects in mammals, while trace elements such as cobalt, copper, iron, manganese, selenium and zinc are considered essential. Given the importance of metals/metalloids in nutrition and human health, the present review was aimed at assessing the relationship between various essential and toxic metals/metalloids and the health outcomes related with the COVID-19. We are in the position to conclude that particular attention must be paid to the load/levels of essential trace elements in COVID-19 patients, mainly zinc and selenium. On the other hand, the exposure to air pollutants in general, and toxic metal/metalloids in particular, should be avoided as much as possible to reduce the possibilities of viral infections, including SARS-CoV-2.
Thematic Areas: Toxicology; Saúde coletiva; Química; Odontología; Nutrição; Medicine (miscellaneous); Medicina veterinaria; Medicina iii; Medicina ii; Medicina i; Materiais; Interdisciplinar; Food science & technology; Food science; Farmacia; Ensino; Engenharias iv; Engenharias ii; Enfermagem; Educação física; Ciências biológicas iii; Ciências biológicas ii; Ciências biológicas i; Ciências ambientais; Ciências agrárias i; Ciência de alimentos; Biotecnología; Biodiversidade; Astronomia / física
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: montserrat.marques@urv.cat; joseluis.domingo@urv.cat
Record's date: 2025-03-15
Paper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://www.sciencedirect.com/science/article/pii/S0278691521001940?via%3Dihub
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Paper original source: Food And Chemical Toxicology. 152 (112161): 112161-
APA: Domingo, Jose L; Marques, Montse (2021). The effects of some essential and toxic metals/metalloids in COVID-19: A review. Food And Chemical Toxicology, 152(112161), 112161-. DOI: 10.1016/j.fct.2021.112161
Article's DOI: 10.1016/j.fct.2021.112161
Entity: Universitat Rovira i Virgili
Journal publication year: 2021
Publication Type: Journal Publications
Repositori URV