Author, as appears in the article.: Fu, Yandi; Pessagno, Federica; Manesiotis, Panagiotis; Borrull, Francesc; Fontanals, Nuria; Maria Marce, Rosa
Department: Química Analítica i Química Orgànica
URV's Author/s: Borrull Ballarín, Francesc / Fontanals Torroja, Núria / Fu, Yandi / Marcé Recasens, Rosa Maria
Keywords: Waste-water Synthetic cathinones Solid-phase extraction Resolution Psychoactive substances Molecularly imprinted polymer Mass-spectrometry Liquid-chromatography Ephedrine Environmental water Enantiomeric determination Cathinones Amphetamine (-)-ephedrine
Abstract: In this study, a series of molecularly imprinted polymers (MIPs) were synthesised using (1R,2S)-(-)-ephedrine or (15,2S)-(+)-pseudoephedrine as template, methacrylic acid as functional monomer and ethylene glycol dimethacrylate as cross-linking agent. A highly selective and sensitive method using the best performing MIP as sorbent in the solid-phase extraction (SPE) followed by liquid chromatography-high resolution mass spectrometry was established for the enantiomeric determination of five cathinones in river water samples. The SPE parameters (sample loading volume and pH, washing and elution solutions) were optimised so that recoveries and selectivities for the analytes were high. The enantioselectivity of MIPs towards the enantiomers of the analytes during the SPE process was also investigated. Under optimal conditions, the method developed provided satisfactory recoveries ranging from 67.6 to 83.2 % with a negligible matrix effect ranging from -5.5 to 1.8 %. The detection limits ranged from 0.3 to 0.8 ng/L and quantification limits ranged from 1.0 to 2.0 ng/L. The application of the method to the analysis of the river water samples indicated that methedmne and butylone were present at low concentration levels in river water samples.
Thematic Areas: Spectroscopy Saúde coletiva Química Odontología Nutrição Medicina ii Medicina i Materiais Interdisciplinar Geociências Farmacia Engenharias iv Engenharias iii Engenharias ii Engenharias i Enfermagem Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Chemistry, analytical Biotecnología Biodiversidade Astronomia / física Analytical chemistry Administração pública e de empresas, ciências contábeis e turismo
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: yandi.fu@estudiants.urv.cat nuria.fontanals@urv.cat nuria.fontanals@urv.cat rosamaria.marce@urv.cat francesc.borrull@urv.cat
Author identifier: 0000-0002-7534-1964 0000-0002-7534-1964 0000-0002-5667-2899 0000-0003-2718-9336
Record's date: 2024-10-12
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://www.sciencedirect.com/science/article/pii/S0026265X21011863?via%3Dihub
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Microchemical Journal. 175 107100-
APA: Fu, Yandi; Pessagno, Federica; Manesiotis, Panagiotis; Borrull, Francesc; Fontanals, Nuria; Maria Marce, Rosa (2022). Preparation and evaluation of molecularly imprinted polymers as selective SPE sorbents for the determination of cathinones in river water. Microchemical Journal, 175(), 107100-. DOI: 10.1016/j.microc.2021.107100
Article's DOI: 10.1016/j.microc.2021.107100
Entity: Universitat Rovira i Virgili
Journal publication year: 2022
Publication Type: Journal Publications
Repositori URV