Articles producció científica> Química Analítica i Química Orgànica

A new analytical method to determine trace level concentrations of pharmaceuticals in influent wastewater: A tool to monitor human use patterns

  • Identification data

    Identifier: imarina:9326638
  • Authors:

    Fontanals N
    Pocurull E
    Montes R
    González-Mariño I
    Santana-Viera S
    Miró M
    Rico A
    Rodríguez-Mozaz S
    Borrull F
    Benito Quintana J
    Maria Marcé R
    Microchemical Journal
    10.1016/j.microc.2023.109131
    Microchemical Journal. 193
  • Others:

    Author, as appears in the article.: Fontanals N; Pocurull E; Montes R; González-Mariño I; Santana-Viera S; Miró M; Rico A; Rodríguez-Mozaz S; Borrull F; Benito Quintana J; Maria Marcé R
    Department: Química Analítica i Química Orgànica
    URV's Author/s: Borrull Ballarín, Francesc / Fontanals Torroja, Núria / Marcé Recasens, Rosa Maria / Pocurull Aixala, Eva
    Keywords: Wastewater-based epidemiology Solid-phase extraction Pharmaceuticals Metabolites Liquid chromatography-tandem mass spectrometry Influent wastewater wastewater-based epidemiology solid-phase extraction products liquid chromatography-tandem mass spectrometry influent wastewater illicit epidemiology environment biomarkers
    Abstract: The occurrence of pharmaceuticals in influent wastewater samples (IWW) is a recurrent issue. The monitoring of their presence is not only valuable from an environmental point of view, but also as a tool to analyze patterns of human use by the so-called wastewater-based epidemiology. The development of an analytical method based on solid-phase extraction followed by liquid chromatography coupled to tandem mass spectrometry to monitor the occurrence of a group of seventeen pharmaceuticals including the most representative for various therapeutic families in IWW samples is described in this work. The samples were collected during a monitoring week in six wastewater treatment plants located in different cities and towns across Spain. The developed method provides acceptable figures of merit with apparent recoveries in IWW ranging from 42% to 139%, and low matrix effect (in general lower than ± 30%), and method quantification limits (MQL) between 1 ng/L and 24 ng/L for all compounds, except atenolol (58 ng/L). All the studied pharmaceuticals were found in all samples with concentrations ranging from < MQL to 10,393 ng/L, being the highest concentrations for tramadol. The population normalized daily loads revealed that the use of pharmaceuticals follows, in general, a similar pattern in all cities monitored.
    Thematic Areas: Spectroscopy Saúde coletiva Química Odontología Nutrição Medicina ii Medicina i Materiais Interdisciplinar Geociências Farmacia Engenharias iv Engenharias iii Engenharias ii Engenharias i Enfermagem Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Chemistry, analytical Biotecnología Biodiversidade Astronomia / física Analytical chemistry Administração pública e de empresas, ciências contábeis e turismo
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    Author's mail: nuria.fontanals@urv.cat nuria.fontanals@urv.cat eva.pocurull@urv.cat rosamaria.marce@urv.cat francesc.borrull@urv.cat
    Author identifier: 0000-0002-7534-1964 0000-0002-7534-1964 0000-0001-5123-995X 0000-0002-5667-2899 0000-0003-2718-9336
    Record's date: 2024-07-20
    Papper version: info:eu-repo/semantics/publishedVersion
    Link to the original source: https://www.sciencedirect.com/science/article/pii/S0026265X23007506?via%3Dihub
    Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/
    Papper original source: Microchemical Journal. 193
    APA: Fontanals N; Pocurull E; Montes R; González-Mariño I; Santana-Viera S; Miró M; Rico A; Rodríguez-Mozaz S; Borrull F; Benito Quintana J; Maria Marcé R (2023). A new analytical method to determine trace level concentrations of pharmaceuticals in influent wastewater: A tool to monitor human use patterns. Microchemical Journal, 193(), -. DOI: 10.1016/j.microc.2023.109131
    Article's DOI: 10.1016/j.microc.2023.109131
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2023
    Publication Type: Journal Publications
  • Keywords:

    Analytical Chemistry,Chemistry, Analytical,Spectroscopy
    Wastewater-based epidemiology
    Solid-phase extraction
    Pharmaceuticals
    Metabolites
    Liquid chromatography-tandem mass spectrometry
    Influent wastewater
    wastewater-based epidemiology
    solid-phase extraction
    products
    liquid chromatography-tandem mass spectrometry
    influent wastewater
    illicit
    epidemiology
    environment
    biomarkers
    Spectroscopy
    Saúde coletiva
    Química
    Odontología
    Nutrição
    Medicina ii
    Medicina i
    Materiais
    Interdisciplinar
    Geociências
    Farmacia
    Engenharias iv
    Engenharias iii
    Engenharias ii
    Engenharias i
    Enfermagem
    Ciências biológicas iii
    Ciências biológicas ii
    Ciências biológicas i
    Ciências ambientais
    Ciências agrárias i
    Ciência de alimentos
    Chemistry, analytical
    Biotecnología
    Biodiversidade
    Astronomia / física
    Analytical chemistry
    Administração pública e de empresas, ciências contábeis e turismo
  • Documents:

  • Cerca a google

    Search to google scholar