Articles producció científica> Química Analítica i Química Orgànica

Solid-phase extraction followed by liquid chromatography-high resolution mass spectrometry to determine synthetic cathinones in different types of environmental waters

  • Datos identificativos

    Identificador: PC:3019
    Autores:
    Marcé, R. M.Fontanals, N.Borrull, F.
    Resumen:
    Synthetic cathinones have become popular in recent years, which would explain why their determination in influent sewage samples has already been documented. In the present study a method based on solid-phase extraction followed by liquid chromatography and high resolution mass spectrometry is developed, validated and applied to determine twelve cathinones and one of their metabolites in different environmental samples including influent and effluent sewage and river water. Two cation-exchange sorbents (Oasis MCX and Oasis WCX) were compared, with better results achieved with Oasis WCX in terms of apparent recoveries (70–100%) and matrix effects (lower than −34%). The method was validated with effluent sewage samples providing suitable figures of merit, with method quantification limits ranging from 1 ng/L to 5 ng/L and method detection limits from 0.1 ng/L to 0.5 ng/L for all the compounds. Of the different cathinones studied, three, namely methylone, mephedrone metabolite and methylenedioxypyrovalerone, were quantified at concentration levels of low ng/L in each of the different samples analysed, while a number of the other cathinones were also detected in some of the samples.
  • Otros:

    Autor según el artículo: Marcé, R. M. ; Fontanals, N. ; Borrull, F.
    Departamento: Química Analítica i Química Orgànica
    Autor/es de la URV: MARCÉ RECASENS, ROSA MARIA; Fontanals, N. ; BORRULL BALLARÍN, FRANCESC
    Palabras clave: Synthetic cathinones Solid-phase extraction Weak cation-exchange
    Resumen: Synthetic cathinones have become popular in recent years, which would explain why their determination in influent sewage samples has already been documented. In the present study a method based on solid-phase extraction followed by liquid chromatography and high resolution mass spectrometry is developed, validated and applied to determine twelve cathinones and one of their metabolites in different environmental samples including influent and effluent sewage and river water. Two cation-exchange sorbents (Oasis MCX and Oasis WCX) were compared, with better results achieved with Oasis WCX in terms of apparent recoveries (70–100%) and matrix effects (lower than −34%). The method was validated with effluent sewage samples providing suitable figures of merit, with method quantification limits ranging from 1 ng/L to 5 ng/L and method detection limits from 0.1 ng/L to 0.5 ng/L for all the compounds. Of the different cathinones studied, three, namely methylone, mephedrone metabolite and methylenedioxypyrovalerone, were quantified at concentration levels of low ng/L in each of the different samples analysed, while a number of the other cathinones were also detected in some of the samples.
    Grupo de investigación: Grup de Cromatografia. Aplicacions Mediambientals
    Áreas temáticas: Química Química Chemistry
    Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 0021-9673
    Identificador del autor: 0000-0002-5667-2899; ; 0000-0003-2718-9336
    Fecha de alta del registro: 2018-02-28
    Página final: 73
    Volumen de revista: 1524
    Versión del articulo depositado: info:eu-repo/semantics/acceptedVersion
    Enlace a la fuente original: https://www.sciencedirect.com/science/article/abs/pii/S0021967317314590?via%3Dihub
    Programa de financiación: plan; Excelencia; CTQ2014-52617-P)
    URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
    DOI del artículo: 10.1016/j.chroma.2017.10.002
    Entidad: Universitat Rovira i Virgili
    Año de publicación de la revista: 2017
    Página inicial: 66
    Tipo de publicación: Article Artículo Article
  • Palabras clave:

    Extracció (química)
    Cations
    Synthetic cathinones
    Solid-phase extraction
    Weak cation-exchange
    Química
    Química
    Chemistry
    0021-9673
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