Autor según el artículo: Andrade, F.J.; Parrilla, M.; Cánovas, R.

Departamento: Química Analítica i Química Orgànica

Autor/es de la URV: ANDRADE , FRANCISCO JAVIER; Parrilla, M.; Cánovas, R.

Resumen: A novel paper-based potentiometric sensor with an enhanced response for the detection of glucose in biological fluids is presented. The electrode consists on platinum sputtered on a filter paper and a Nafion membrane to immobilize the enzyme glucose oxidase. The response obtained is proportional to the logarithm of the concentration of glucose, with a sensitivity of -119±8 mV·decade-1, a linear range that spans from 10-4M to 10-2.5 M and a limit of detection of 10-4.5 M of glucose. It is shown that Nafion increases the sensitivity of the technique while minimizing interferences. Validation with human serum samples shows an excellent agreement when compared to standard methods. This approach can become an interesting alternative for the development of simple and affordable devices for point of care and home-based diagnostics.

Grupo de investigación: Grup de Quimiometria, Qualimetria i Nanosensors

Áreas temáticas: Química Química Chemistry

Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/

ISSN: 0956-5663

Identificador del autor: 0000-0003-1199-2837; 0000-0002-1344-8432; 0000-0001-9552-535X

Fecha de alta del registro: 2018-04-30

Versión del articulo depositado: info:eu-repo/semantics/submittedVersion

Enlace a la fuente original: https://www.sciencedirect.com/science/article/pii/S0956566316311745?via%3Dihub

Programa de financiación: plan; CTQ2013-46464-R altres; EU-Marie Curie Grant; PCIG09-GA-2011-293538 altres; Gencat fellowship; FI; FI_B 00079 altres; URV Martí i Franqués; PMF-PIPF; 2013PMF-PIPF-16

DOI del artículo: 10.1016/j.bios.2016.11.034

Entidad: Universitat Rovira i Virgili

Año de publicación de la revista: 2016

Tipo de publicación: Article Artículo Article