Autor según el artículo: López-Martínez, G. Rodríguez-Porrata, B. Margalef-Català, M. Cordero-Otero, R.

Departamento: Bioquímica i Biotecnologia

Autor/es de la URV: Gema López-Martínez, Boris Rodríguez-Porrata, Mar Margalef-Català, Ricardo Cordero-Otero

Resumen: The yeast Saccharomyces cerevisiae is able to overcome cell dehydration; cell metabolic activity is arrested during this period but restarts after rehydration. The yeast genes encoding hydrophilin proteins were characterised to determine their roles in the dehydration-resistant phenotype, and STF2p was found to be a hydrophilin that is essential for survival after the desiccation-rehydration process. Deletion of STF2 promotes the production of reactive oxygen species and apoptotic cell death during stress conditions, whereas the overexpression of STF2, whose gene product localises to the cytoplasm, results in a reduction in ROS production upon oxidative stress as the result of the antioxidant capacity of the STF2p protein.

Áreas temáticas: Saccharomyces cerevisiae protein

Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/

ISSN: 1932-6203

Volumen de revista: 7

Versión del articulo depositado: info:eu-repo/semantics/publishedVersion

Enlace a la fuente original: http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0033324

DOI del artículo: 10.1371/journal.pone.0033324

Entidad: Universitat Rovira i Virgili.

Año de publicación de la revista: 2012