Autor según el artículo: Lanuza M; Tomàs J; Garcia N; Cilleros-Mañé V; Just-Borràs L; Tomás M
Departamento: Ciències Mèdiques Bàsiques
Autor/es de la URV: Cilleros Mañé, Víctor / Garcia Sancho, Maria de les Neus / Just Borràs, Laia / Lanuza Escolano, María Angel / Tomás Ferré, José Maria / Tomas Marginet, Marta
Palabras clave: Hashtag Etiqueta «#» @uroweb @residentesaeu @infoAeu
Resumen: © 2018 Elsevier Ltd Early in development, each muscle fiber is innervated by multiple neurons. Different activities between nerve terminals on the same junction cause the elimination of all but one of them through Hebbian competition. The molecular basis of this developmental synapse modulation is still being investigated because it is a model for how the nervous system achieves the proper synaptic connectivity and function. The study of the vertebrate neuromuscular junction has proven useful to understand the carefully regulated process of axon withdrawal, locally regulated in the synaptic site by the nerve terminals themselves, the postsynaptic muscle cell and the Schwann cells. In this review, we summarize the multiple factors that have been implicated in axonal competition and synapse elimination.
Áreas temáticas: Physiology (medical) Physiology
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 24688673
Direcció de correo del autor: laia.just@urv.cat marta.tomas@urv.cat victor.cilleros@alumni.urv.cat josepmaria.tomas@urv.cat laia.just@urv.cat mariaangel.lanuza@urv.cat
Identificador del autor: 0000-0003-0473-3730 0000-0002-4151-1697 0000-0001-5690-9932 0000-0002-0406-0006 0000-0003-0473-3730 0000-0003-4795-4103
Fecha de alta del registro: 2024-10-12
Versión del articulo depositado: info:eu-repo/semantics/acceptedVersion
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
Referencia al articulo segun fuente origial: Curr Opin Physiol. 4 25-31
Referencia de l'ítem segons les normes APA: Lanuza M; Tomàs J; Garcia N; Cilleros-Mañé V; Just-Borràs L; Tomás M (2018). Axonal competition and synapse elimination during neuromuscular junction development. Curr Opin Physiol, 4(), 25-31. DOI: 10.1016/j.cophys.2018.04.001
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2018
Tipo de publicación: Journal Publications
Repositori URV