Autor según el artículo: Lanuza M; Tomàs J; Garcia N; Cilleros-Mañé V; Just-Borràs L; Tomás M

Departamento: Ciències Mèdiques Bàsiques

Autor/es de la URV: Cilleros Mañé, Víctor / Garcia Sancho, Maria de les Neus / Just Borràs, Laia / Tomas Marginet, Marta

Palabras clave: Hashtag Etiqueta «#» @uroweb @residentesaeu @infoAeu

Resumen: © 2018 Elsevier Ltd Early in development, each muscle fiber is innervated by multiple neurons. Different activities between nerve terminals on the same junction cause the elimination of all but one of them through Hebbian competition. The molecular basis of this developmental synapse modulation is still being investigated because it is a model for how the nervous system achieves the proper synaptic connectivity and function. The study of the vertebrate neuromuscular junction has proven useful to understand the carefully regulated process of axon withdrawal, locally regulated in the synaptic site by the nerve terminals themselves, the postsynaptic muscle cell and the Schwann cells. In this review, we summarize the multiple factors that have been implicated in axonal competition and synapse elimination.

Áreas temáticas: Physiology (medical) Physiology

Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/

ISSN: 24688673

Direcció de correo del autor: victor.cilleros@urv.cat marta.tomas@urv.cat laia.just@urv.cat victor.cilleros@urv.cat

Identificador del autor: 0000-0001-5690-9932 0000-0002-4151-1697 0000-0003-0473-3730 0000-0001-5690-9932

Fecha de alta del registro: 2023-09-02

Versión del articulo depositado: info:eu-repo/semantics/acceptedVersion

Enlace a la fuente original: https://www.sciencedirect.com/science/article/pii/S2468867318300543?via%3Dihub

URL Documento de licencia: http://repositori.urv.cat/ca/proteccio-de-dades/

Referencia al articulo segun fuente origial: Curr Opin Physiol. 4 25-31

Referencia de l'ítem segons les normes APA: Lanuza M; Tomàs J; Garcia N; Cilleros-Mañé V; Just-Borràs L; Tomás M (2018). Axonal competition and synapse elimination during neuromuscular junction development. Curr Opin Physiol, 4(), 25-31. DOI: 10.1016/j.cophys.2018.04.001

DOI del artículo: 10.1016/j.cophys.2018.04.001

Entidad: Universitat Rovira i Virgili

Año de publicación de la revista: 2018

Tipo de publicación: Journal Publications