Autor según el artículo: Fontanals, N; Marce, R M; Borrull, F
Departamento: Química Analítica i Química Orgànica
Autor/es de la URV: Borrull Ballarín, Francesc / Fontanals Torroja, Núria / Marcé Recasens, Rosa Maria
Palabras clave: Weak cation-exchange Waste-water Urine Synthetic cathinones Solid-phase extraction Solid phase extraction Quantification Psychoactive substances Orbitrap Metabolites Liquid chromatography-orbitrap-high resolution mass spectrometry Liquid chromatography Identification Environmental water samples Designer drugs Derivatives Cathinones Blood Abuse synthetic cathinones solid-phase extraction orbitrap liquid chromatography environmental water samples
Resumen: Synthetic cathinones have become popular in recent years, which would explain why their determination in influent sewage samples has already been documented. In the present study a method based on solid-phase extraction followed by liquid chromatography and high resolution mass spectrometry is developed, validated and applied to determine twelve cathinones and one of their metabolites in different environmental samples including influent and effluent sewage and river water. Two cation-exchange sorbents (Oasis MCX and Oasis WCX) were compared, with better results achieved with Oasis WCX in terms of apparent recoveries (70-100%) and matrix effects (lower than −34%). The method was validated with effluent sewage samples providing suitable figures of merit, with method quantification limits ranging from 1 ng/L to 5 ng/L and method detection limits from 0.1 ng/L to 0.5 ng/L for all the compounds. Of the different cathinones studied, three, namely methylone, mephedrone metabolite and methylenedioxypyrovalerone, were quantified at concentration levels of low ng/L in each of the different samples analysed, while a number of the other cathinones were also detected in some of the samples.
Áreas temáticas: Zootecnia / recursos pesqueiros Química Organic chemistry Nutrição Medicine (miscellaneous) Medicina veterinaria Medicina ii Medicina i Materiais Interdisciplinar Geociências General medicine Farmacia Engenharias ii Engenharias i Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Chemistry, analytical Biotecnología Biodiversidade Biochemistry Biochemical research methods Analytical chemistry
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 0021-9673
Direcció de correo del autor: nuria.fontanals@urv.cat nuria.fontanals@urv.cat rosamaria.marce@urv.cat francesc.borrull@urv.cat
Identificador del autor: 0000-0002-7534-1964 0000-0002-7534-1964 0000-0002-5667-2899 0000-0003-2718-9336
Fecha de alta del registro: 2024-10-12
Versión del articulo depositado: info:eu-repo/semantics/acceptedVersion
Enlace a la fuente original: https://www.sciencedirect.com/science/article/abs/pii/S0021967317314590?via%3Dihub
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
Referencia al articulo segun fuente origial: Journal Of Chromatography a. 1524 66-73
Referencia de l'ítem segons les normes APA: Fontanals, N; Marce, R M; Borrull, F (2017). Solid-phase extraction followed by liquid chromatography-high resolution mass spectrometry to determine synthetic cathinones in different types of environmental waters samples. Journal Of Chromatography a, 1524(), 66-73. DOI: 10.1016/j.chroma.2017.10.002
DOI del artículo: 10.1016/j.chroma.2017.10.002
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2017
Tipo de publicación: Journal Publications
Repositori URV