Autor según el artículo: Sahebkar, Amirhossein; Sancho, Elena; Abello, David; Camps, Jordi; Joven, Jorge;
Departamento: Medicina i Cirurgia
Autor/es de la URV: Camps Andreu, Jorge / Joven Maried, Jorge
Palabras clave: Α-ketoglutarate Non-alcoholic fatty liver disease Diagnosis Ck18-f Biomarker ?-ketoglutarate non-alcoholic fatty liver disease diagnosis ck18-f biomarker
Resumen: © 2017 Wiley Periodicals, Inc. Currently, a liver biopsy remains the only reliable way to precisely diagnose non-alcoholic fatty liver disease (NAFLD) and establish the severity of liver injury, presence of fibrosis, and architecture remodeling. However, the cost and the intrinsic invasive procedure of a liver biopsy rules it out as a gold standard diagnostic test, and the imaging test are not the best choice due to the price, and currently is being refined. The lack of a biomarker of NAFLD pushes to develop this new line of research. The aim of the present systematic review is to clarify and update all the NAFLD biomarkers described in the literature until recently. We highlight α-ketoglutarate and CK18-F as currently the best potential biomarker of NAFLD. However, due to methodological differences, we propose the implementation of international, multicenter, multiethnic studies with larger population size, and biopsy proven NAFLD diagnosis to analyze and compare α-ketoglutarate and CK18-F as potential biomarkers of the silent evolution of NAFLD.
Áreas temáticas: Química Physiology Odontología Nutrição Medicina veterinaria Medicina iii Medicina ii Medicina i Interdisciplinar Farmacia Enfermagem Educação física Clinical biochemistry Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciência de alimentos Ciência da computação Cell biology Biotecnología Biodiversidade
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 00219541
Direcció de correo del autor: jorge.camps@urv.cat jorge.joven@urv.cat
Identificador del autor: 0000-0002-3165-3640 0000-0003-2749-4541
Fecha de alta del registro: 2024-09-07
Versión del articulo depositado: info:eu-repo/semantics/acceptedVersion
Enlace a la fuente original: https://onlinelibrary.wiley.com/doi/abs/10.1002/jcp.25779
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
Referencia al articulo segun fuente origial: Journal Of Cellular Physiology. 233 (2): 849-855
Referencia de l'ítem segons les normes APA: Sahebkar, Amirhossein; Sancho, Elena; Abello, David; Camps, Jordi; Joven, Jorge; (2018). Novel circulating biomarkers for non-alcoholic fatty liver disease: A systematic review.. Journal Of Cellular Physiology, 233(2), 849-855. DOI: 10.1002/jcp.25779
DOI del artículo: 10.1002/jcp.25779
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2018
Tipo de publicación: Journal Publications
Repositori URV