Autor según el artículo: González N; Marquès M; Cunha SC; Fernandes JO; Domingo JL; Nadal M
Departamento: Ciències Mèdiques Bàsiques
Autor/es de la URV: Domingo Roig, José Luis / Gonzalez Paradell, Nieves / Marquès Bueno, Montserrat / Nadal Lomas, Martí
Palabras clave: Urine Thermal paper Taihu lake Prenatal exposure Occupational-exposure Mass-spectrometry Human urine Human health Human exposure Endocrine-disrupting chemicals Duplicate diet Bpa Bisphenol analogues Biomonitoring A bpa duplicate diet bpa bisphenol analogues biomonitoring
Resumen: © 2020 The Authors For non-occupationally exposed adults, dietary intake is the main route of exposure to bisphenols (BPs), with canned foodstuffs playing a key role. This study was aimed at biomonitoring bisphenol A (BPA) and 5 more BP analogues (BPB, BPE, BPF, BPAF and BPZ) in spot urine and blood samples of a cohort of adults, who followed a diet based on a high consumption of canned food. To the best of our knowledge, this is the first study aimed at assessing the co-exposure of BP analogues in food and biological samples after a two-day duplicate diet study. The estimated total dietary exposure was 0.37 and 0.045 µg/kg body weight/day, for the canned-diet and control groups, respectively. BPA was the compound with the highest concentration in urine in comparison with the values of the remaining BP analogues. A high detection rate of BPA was noted in urine for both groups, 96% for the canned-diet group and 90% for the control group, while in blood it could be only quantified in 6% of the samples. The identification of other analogues was hardly related to diet, so it could be the result of other potential exposure sources, such as personal care products (PCPs) or air inhalation. After 2 days, the excretion of BPA was considerably higher in the canned-diet group subjects than those in the control group (7.02 vs. 1.89 µg/day), confirming that diet and canned foodstuffs are the main route of exposure to BPA. Anyhow, the temporary tolerable daily intake (t-TDI) established by the EFSA was not exceeded, even by those consumers with a diet rich in canned food. Moreover, spot urine samples provided accurate information about exposure and excretion of BPA, being the 4 h, instead of 24 h, the optimal sampling interval, when the collection of spot urine samples is not possible.
Áreas temáticas: Zootecnia / recursos pesqueiros Saúde coletiva Química Medicina iii Medicina ii Medicina i Interdisciplinar Geociências General medicine General environmental science Farmacia Environmental sciences Environmental science (miscellaneous) Environmental science (all) Engenharias iv Engenharias ii Engenharias i Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Biotecnología Biodiversidade Astronomia / física Administração pública e de empresas, ciências contábeis e turismo
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 01604120
Direcció de correo del autor: marti.nadal@urv.cat nieves.gonzalez@urv.cat montserrat.marques@urv.cat marti.nadal@urv.cat joseluis.domingo@urv.cat
Identificador del autor: 0000-0002-0217-4827 0000-0003-4134-016X 0000-0001-6302-8578 0000-0002-0217-4827 0000-0001-6647-9470
Fecha de alta del registro: 2024-06-15
Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
Enlace a la fuente original: https://www.sciencedirect.com/science/article/pii/S0160412020306954
Referencia al articulo segun fuente origial: Environment International. 140 (UNSP 105760): 105760-
Referencia de l'ítem segons les normes APA: González N; Marquès M; Cunha SC; Fernandes JO; Domingo JL; Nadal M (2020). Biomonitoring of co-exposure to bisphenols by consumers of canned foodstuffs. Environment International, 140(UNSP 105760), 105760-. DOI: 10.1016/j.envint.2020.105760
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
DOI del artículo: 10.1016/j.envint.2020.105760
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2020
Tipo de publicación: Journal Publications