Autor según el artículo: Nadal, Joan Carles; Anderson, Kimberley L; Dargo, Stuart; Joas, Irvin; Salas, Daniela; Borrull, Francesc; Cormack, Peter A G; Marce, Rosa Maria; Fontanals, Nuria
Departamento: Química Analítica i Química Orgànica
Autor/es de la URV: Borrull Ballarín, Francesc / Fontanals Torroja, Núria / Marcé Recasens, Rosa Maria / SALAS ACOSTA, DANIELA
Palabras clave: Waste-water Surface Sorbent Solid-phase extraction Silica Selective extraction Pharmaceuticals Nonsteroidal antiinflammatory drugs Monodisperse Mixed-mode ion-exchange Liquid-chromatography Exchange character Environmental water samples Basic analytes Amphoteric sorbent Acidic analytes
Resumen: Solid-phase extraction (SPE) is a widely-used and very well-established sample preparation technique for liquid samples. An area of on-going focus for innovation in this field concerns the development of new and improved SPE sorbents that can enhance the sensitivity and/or the selectivity of SPE processes. In this context, mixed-mode ion-exchange sorbents have been developed and commercialised, thereby allowing enhanced capacity and selectivity to be offered by one single material. The ion-selectivity of these materials is such that either anion-exchange or cation-exchange is possible, however one limitation to their use is that more than one sorbent type is required to capture both anions and cations. In this paper, we disclose the design, synthesis and exploitation of a novel SPE sorbent based on microporous polymer microspheres with amphoteric character. We show that it is possible to switch the ion-exchange retention mechanism of the sorbent simply by changing the pH of the loading solution; anion-exchange dominates at low pH, cation-exchange dominates at high pH, and both mechanisms can contribute to retention when the polymer-bound amphoteric species, which are based on the alpha-amino acid sarcosine (N-methylglycine), are in a zwitterionic state. This is an interesting and useful feature, since it allows distinctly different groups of analytes (acids and bases) to be fractionated using one single amphoteric sorbent with dual-functionality. The sarcosine-based sorbent was applied to the SPE of acidic, basic and amphoteric analytes from ultrapure water, river water and effluent wastewater samples. Under optimised conditions (loading 100 mL of sample at pH 6, washing with 1 mL of MeOH and eluting with an acidic or basic additive in MeOH) the recoveries for most of the compounds were from 57% to 87% for river water and from 61% to 88% for effluent wastewater. We anticipate that these results will lay the basis for the development of a new family of multifunctional sorbents, where two or more separation mechanisms can be embedded within one single, bespoke material optimised for application to challenging chemical separations to give significant selectivity advantages over essentially all other state-of-the-art SPE sorbents. (c) 2020 Elsevier B.V. All rights reserved.
Áreas temáticas: Zootecnia / recursos pesqueiros Química Organic chemistry Nutrição Medicine (miscellaneous) Medicina veterinaria Medicina ii Medicina i Materiais Interdisciplinar Geociências General medicine Farmacia Engenharias ii Engenharias i Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Chemistry, analytical Biotecnología Biodiversidade Biochemistry Biochemical research methods Analytical chemistry
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
Direcció de correo del autor: nuria.fontanals@urv.cat nuria.fontanals@urv.cat rosamaria.marce@urv.cat francesc.borrull@urv.cat
Identificador del autor: 0000-0002-7534-1964 0000-0002-7534-1964 0000-0002-5667-2899 0000-0003-2718-9336
Fecha de alta del registro: 2024-10-12
Versión del articulo depositado: info:eu-repo/semantics/acceptedVersion
Enlace a la fuente original: https://www.sciencedirect.com/science/article/abs/pii/S0021967320306269?via%3Dihub
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
Referencia al articulo segun fuente origial: Journal Of Chromatography a. 1626 (461348): 461348-
Referencia de l'ítem segons les normes APA: Nadal, Joan Carles; Anderson, Kimberley L; Dargo, Stuart; Joas, Irvin; Salas, Daniela; Borrull, Francesc; Cormack, Peter A G; Marce, Rosa Maria; Fonta (2020). Microporous polymer microspheres with amphoteric character for the solid-phase extraction of acidic and basic analytes. Journal Of Chromatography a, 1626(461348), 461348-. DOI: 10.1016/j.chroma.2020.461348
DOI del artículo: 10.1016/j.chroma.2020.461348
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2020
Tipo de publicación: Journal Publications
Repositori URV