Autor según el artículo: Castro-Torres, Ruben Dario; Busquets, Oriol; Parcerisas, Antoni; Verdaguer, Ester; Olloquequi, Jordi; Etchetto, Miren; Beas-Zarate, Carlos; Folch, Jaume; Camins, Antoni; Auladell, Carme;

Departamento: Bioquímica i Biotecnologia

Autor/es de la URV: Folch Lopez, Jaume

Palabras clave: Wdr62 Synaptogenesis Synaptic function Signaling pathway Scg10 Scaffold proteins Phosphorylation Nmdar N-terminal kinase Migration Map1b Jnk1 Induced neurite outgrowth Distinct roles Dcx Axon elongation Asymmetric division Activation wdr62 scg10 nmdar migration map1b jnk1 dcx asymmetric division

Resumen: The c-Jun N-terminal Kinases (JNKs) are a group of regulatory elements responsible for the control of a wide array of functions within the cell. In the central nervous system (CNS), JNKs are involved in neuronal polarization, starting from the cell division of neural stem cells and ending with their final positioning when migrating and maturing. This review will focus mostly on isoform JNK1, the foremost contributor of total JNK activity in the CNS. Throughout the text, research from multiple groups will be summarized and discussed in order to describe the involvement of the JNKs in the different steps of neuronal polarization. The data presented support the idea that isoform JNK1 is highly relevant to the regulation of many of the processes that occur in neuronal development in the CNS.

Áreas temáticas: Medicine (miscellaneous) Cell biology Biochemistry, genetics and molecular biology (miscellaneous) Biochemistry, genetics and molecular biology (all)

Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/

ISSN: 20734409

Direcció de correo del autor: jaume.folch@urv.cat

Identificador del autor: 0000-0002-5051-8858

Fecha de alta del registro: 2023-04-15

Versión del articulo depositado: info:eu-repo/semantics/publishedVersion

Enlace a la fuente original: https://www.mdpi.com/2073-4409/9/8/1897

URL Documento de licencia: http://repositori.urv.cat/ca/proteccio-de-dades/

Referencia al articulo segun fuente origial: Cells. 9 (8):

Referencia de l'ítem segons les normes APA: Castro-Torres, Ruben Dario; Busquets, Oriol; Parcerisas, Antoni; Verdaguer, Ester; Olloquequi, Jordi; Etchetto, Miren; Beas-Zarate, Carlos; Folch, Jau (2020). Involvement of JNK1 in Neuronal Polarization During Brain Development. Cells, 9(8), -. DOI: 10.3390/cells9081897

DOI del artículo: 10.3390/cells9081897

Entidad: Universitat Rovira i Virgili

Año de publicación de la revista: 2020

Tipo de publicación: Journal Publications