Autor según el artículo: Paz-Graniel I; Babio N; Becerra-Tomás N; Toledo E; Camacho-Barcia L; Corella D; Castañer-Niño O; Romaguera D; Vioque J; Alonso-Gómez ÁM; Wärnberg J; Martínez JA; Serra-Majem L; Estruch R; Tinahones FJ; Fernandez-Aranda F; Lapetra J; Pintó X; Tur JA; García-Rios A; Bueno-Cavanillas A; Gaforio JJ; Matía-Martín P; Daimiel L; Sánchez VM; Vidal J; Prieto-Sanchez L; Ros E; Razquin C; Mestres C; Sorli JV; Cuenca-Royo AM; Rios A; Torres-Collado L; Vaquero-Luna J; Pérez-Farinós N; Zulet MA; Sanchez-Villegas A; Casas R; Bernal-Lopez MR; Santos-Lozano JM; Corbella X; Mateos D; Buil-Cosiales P; Jiménez-Murcia S; Fernandez-Carrion R; Forcano-Gamazo L; López M; Sempere-Pascual MÁ; Moreno-Rodriguez A; Gea A; de la Torre-Fornell R; Salas-Salvadó J; PREDIMED-Plus Investigators

Departamento: Bioquímica i Biotecnologia

Autor/es de la URV: Babio Sánchez, Nancy Elvira / Becerra Tomás, Nerea / Díaz López, Andres / Paz Graniel, Indira del Socorro / Salas Salvadó, Jorge

Palabras clave: Validation Risk Predimed-plus Physical-activity questionnaire Older Mini-mental state examination Mini-mental state Impairment Disease Dementia Component Cognitive impairment Coffee Caffeine Benefits

Resumen: Purpose Coffee is rich in compounds such as polyphenols, caffeine, diterpenes, melanoidins and trigonelline, which can stimulate brain activity. Therefore, the possible association of coffee consumption with cognition is of considerable research interest. In this paper, we assess the association of coffee consumption and total dietary caffeine intake with the risk of poor cognitive functioning in a population of elderly overweight/obese adults with metabolic syndrome (MetS). Methods PREDIMED-plus study participants who completed the Mini-Mental State Examination test (MMSE) (n = 6427; mean age = 65 +/- 5 years) or a battery of neuropsychological tests were included in this cross-sectional analysis. Coffee consumption and total dietary caffeine intake were assessed at baseline using a food frequency questionnaire. Logistic regression models were fitted to evaluate the association between total, caffeinated and decaffeinated coffee consumption or total dietary caffeine intake and cognitive impairment. Results Total coffee consumers and caffeinated coffee consumers had better cognitive functioning than non-consumers when measured by the MMSE and after adjusting for potential confounders (OR 0.63; 95% CI 0.44-0.90 and OR 0.56; 95% CI 0.38-0.83, respectively). Results were similar when cognitive performance was measured using the Clock Drawing Test (CDT) and Trail Making Test B (TMT-B). These associations were not observed for decaffeinated coffee consumption. Participants in the highest tertile of total dietary caffeine intake had lower odds of poor cognitive functioning than those in the reference tertile when screened by the MMSE (OR 0.64; 95% CI 0.47-0.87) or other neurophysiological tests evaluating a variety of cognitive domains (i.e., CDT and TMT-A). Conclusions Coffee consumption and total dietary caffeine intake were associated with better cognitive functioning as measured by various neuropsychological tests in a Mediterranean cohort of elderly individuals with MetS.

Áreas temáticas: Serviço social Saúde coletiva Química Nutrition and dietetics Nutrition & dietetics Nutrição Medicine (miscellaneous) Medicina veterinaria Medicina iii Medicina ii Medicina i Interdisciplinar Farmacia Educação física Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos

Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/

Direcció de correo del autor: indiradelsocorro.paz@urv.cat nerea.becerra@urv.cat andres.diaz@urv.cat nancy.babio@urv.cat jordi.salas@urv.cat indiradelsocorro.paz@urv.cat

Identificador del autor: 0000-0002-4429-6507 0000-0002-7500-5629 0000-0003-3527-5277 0000-0003-2700-7459

Fecha de alta del registro: 2023-02-19

Versión del articulo depositado: info:eu-repo/semantics/acceptedVersion

Enlace a la fuente original: https://link.springer.com/article/10.1007/s00394-020-02415-w

URL Documento de licencia: http://repositori.urv.cat/ca/proteccio-de-dades/

Referencia al articulo segun fuente origial: European Journal Of Nutrition. 60 (5): 2381-2396

Referencia de l'ítem segons les normes APA: Paz-Graniel I; Babio N; Becerra-Tomás N; Toledo E; Camacho-Barcia L; Corella D; Castañer-Niño O; Romaguera D; Vioque J; Alonso-Gómez ÁM; Wärnberg J; M (2021). Association between coffee consumption and total dietary caffeine intake with cognitive functioning: cross-sectional assessment in an elderly Mediterranean population. European Journal Of Nutrition, 60(5), 2381-2396. DOI: 10.1007/s00394-020-02415-w

DOI del artículo: 10.1007/s00394-020-02415-w

Entidad: Universitat Rovira i Virgili

Año de publicación de la revista: 2021

Tipo de publicación: Journal Publications