Articles producció científica> Medicina i Cirurgia

Systematic review of the prognostic utility of D-dimer, disseminated intravascular coagulation, and anticoagulant therapy in COVID-19 critically ill patients

  • Datos identificativos

    Identificador: imarina:9150988
    Autores:
    Moreno, G.Carbonell, R.Bodi, M.Rodriguez, A.
    Resumen:
    During the new pandemic caused by SARS-CoV-2, there is short knowledge regarding the management of different disease areas, such as coagulopathy and interpretation of D-dimer levels, its association with disseminated intravascular coagulation (DIC) and controversy about the benefit of anticoagulation. Thus, a systematic review has been performed to define the role of D-dimer in the disease, the prevalence of DIC and the usefulness of anticoagulant treatment in these patients. A literature search was performed to analyze the studies of COVID-19 patients. Four recommendations were drawn based on expert opinion and scientific knowledge, according to the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach. The present review suggests the presence of higher levels of D-dimer in those with worse prognosis, there may be an overdiagnosis of DIC in the course of the disease and there is no evidence on the benefit of starting anticoagulant treatment based only on isolated laboratory data. (C) 2020 Elsevier Espana, S.L.U. y SEMICYUC. All rights reserved.
  • Otros:

    Autor según el artículo: Moreno, G.; Carbonell, R.; Bodi, M.; Rodriguez, A.;
    Departamento: Medicina i Cirurgia
    Autor/es de la URV: Bodi Saera, Maria Amparo
    Palabras clave: Thrombosis Society Sepsis Management Disseminated intravascular coagulation D-dimer Covid-19 Anticoagulation
    Resumen: During the new pandemic caused by SARS-CoV-2, there is short knowledge regarding the management of different disease areas, such as coagulopathy and interpretation of D-dimer levels, its association with disseminated intravascular coagulation (DIC) and controversy about the benefit of anticoagulation. Thus, a systematic review has been performed to define the role of D-dimer in the disease, the prevalence of DIC and the usefulness of anticoagulant treatment in these patients. A literature search was performed to analyze the studies of COVID-19 patients. Four recommendations were drawn based on expert opinion and scientific knowledge, according to the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach. The present review suggests the presence of higher levels of D-dimer in those with worse prognosis, there may be an overdiagnosis of DIC in the course of the disease and there is no evidence on the benefit of starting anticoagulant treatment based only on isolated laboratory data. (C) 2020 Elsevier Espana, S.L.U. y SEMICYUC. All rights reserved.
    Áreas temáticas: Medicina iii Medicina ii Medicina i General medicine Educação física Critical care medicine Critical care and intensive care medicine
    Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
    Direcció de correo del autor: mariaamparo.bodi@urv.cat mariaamparo.bodi@urv.cat
    Identificador del autor: 0000-0001-7652-8379 0000-0001-7652-8379
    Fecha de alta del registro: 2024-07-27
    Versión del articulo depositado: info:eu-repo/semantics/acceptedVersion
    Enlace a la fuente original: https://www.sciencedirect.com/science/article/abs/pii/S021056912030187X?via%3Dihub#!
    URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
    Referencia al articulo segun fuente origial: Medicina Intensiva. 45 (1): 42-55
    Referencia de l'ítem segons les normes APA: Moreno, G.; Carbonell, R.; Bodi, M.; Rodriguez, A.; (2021). Systematic review of the prognostic utility of D-dimer, disseminated intravascular coagulation, and anticoagulant therapy in COVID-19 critically ill patients. Medicina Intensiva, 45(1), 42-55. DOI: 10.1016/j.medin.2020.06.006
    DOI del artículo: 10.1016/j.medin.2020.06.006
    Entidad: Universitat Rovira i Virgili
    Año de publicación de la revista: 2021
    Tipo de publicación: Journal Publications
  • Palabras clave:

    Critical Care and Intensive Care Medicine,Critical Care Medicine
    Thrombosis
    Society
    Sepsis
    Management
    Disseminated intravascular coagulation
    D-dimer
    Covid-19
    Anticoagulation
    Medicina iii
    Medicina ii
    Medicina i
    General medicine
    Educação física
    Critical care medicine
    Critical care and intensive care medicine
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