Autor según el artículo: Marhuenda-Munoz, Maria; Rinaldi de Alvarenga, Jose Fernando; Hernaez, Alvaro; Tresserra-Rimbau, Anna; Martinez-Gonzalez, Miguel Angel; Salas-Salvado, Jordi; Corella, Dolores; Malcampo, Mireia; Martinez, Jose Alfredo; Alonso-Gomez, Angel M.; Warnberg, Julia; Vioque, Jesus; Romaguera, Dora; Lopez-Miranda, Jose; Estruch, Ramon; Tinahones, Francisco J.; Lapetra, Jose; Serra-Majem, J. Lluis; Bueno-Cavanillas, Aurora; Tur, Josep A.; Sanchez, Vicente Martin; Pinto, Xavier; Delgado-Rodriguez, Miguel; Matia-Martin, Pilar; Vidal, Josep; Vazquez, Clotilde; Daimiel, Lidia; Ros, Emilio; Serra-Mir, Merce; Vazquez-Ruiz, Zenaida; Nishi, Stephanie K.; Sorli, Jose V.; Zomeno, Maria Dolores; Zulet, Maria Angeles; Vaquero-Luna, Jessica; Carabano-Moral, Rosa; Notario-Barandiaran, Leyre; Morey, Marga; Garcia-Rios, Antonio; Gomez-Perez, Ana M.; Santos-Lozano, Jose Manuel; Buil-Cosiales, Pilar; Basora, Josep; Portoles, Olga; Schroder, Helmut; Abete, Itziar; Salaverria-Lete, Itziar; Toledo, Estefania; Babio, Nancy; Fito, Montse; Martinez-Huelamo, Miriam; Lamuela-Raventos, Rosa M.;
Departamento: Bioquímica i Biotecnologia
Autor/es de la URV: Babio Sánchez, Nancy Elvira / Basora Gallisa, Josep / Nishi, Stephanie Kimiko / Salas Salvadó, Jorge
Palabras clave: Predimed-plus study Plasma carotenoids Phytochemicals Mediterranean diet Matrix effect absorption Mass spectrometry Liquid chromatography Dietary fats Bioactive compounds
Resumen: Carotenoids are pigments contained mainly in fruit and vegetables (F&V) that have beneficial effects on cardiometabolic health. Due to their lipophilic nature, co-ingestion of fat appears to increase their bioavailability via facilitating transfer to the aqueous micellar phase during digestion. However, the extent to which high fat intake may contribute to increased carotenoid plasma concentrations is still unclear. The objective was to examine the degree to which the consumption of different amounts of both carotenoid-rich foods and fats is associated with plasma carotenoid concentrations within a Mediterranean lifestyle context (subsample from the PREDIMED-Plus study baseline) where consumption of F&V and fat is high. The study population was categorized into four groups according to their self-reported consumption of F&V and fat. Carotenoids were extracted from plasma samples and analyzed by HPLC-UV-VIS-QqQ-MS/MS. Carotenoid systemic concentrations were greater in high consumers of F&V than in low consumers of these foods (+3.04 mu mol/L (95% CI: 0.90, 5.17), p-value = 0.005), but circulating concentrations seemed to decrease when total fat intake was very high (-2.69 mu mol/L (-5.54; 0.16), p-value = 0.064). High consumption of F&V is associated with greater systemic levels of total carotenoids, in particular when fat intake is low-to-moderate rather than very high.
Áreas temáticas: Química Physiology Molecular biology Medicina ii Medicina i Interdisciplinar Food science & technology Food science Farmacia Engenharias ii Clinical biochemistry Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Chemistry, medicinal Cell biology Biotecnología Biodiversidade Biochemistry & molecular biology Biochemistry
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
Direcció de correo del autor: stephanie.nishi@urv.cat josep.basora@urv.cat josep.basora@urv.cat jordi.salas@urv.cat nancy.babio@urv.cat
Identificador del autor: 0000-0003-2700-7459 0000-0003-3527-5277
Fecha de alta del registro: 2024-07-27
Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
Enlace a la fuente original: https://www.mdpi.com/2076-3921/10/3/473
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
Referencia al articulo segun fuente origial: Antioxidants. 10 (3): 1-14
Referencia de l'ítem segons les normes APA: Marhuenda-Munoz, Maria; Rinaldi de Alvarenga, Jose Fernando; Hernaez, Alvaro; Tresserra-Rimbau, Anna; Martinez-Gonzalez, Miguel Angel; Salas-Salvado, (2021). High Fruit and Vegetable Consumption and Moderate Fat Intake Are Associated with Higher Carotenoid Concentration in Human Plasma. Antioxidants, 10(3), 1-14. DOI: 10.3390/antiox10030473
DOI del artículo: 10.3390/antiox10030473
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2021
Tipo de publicación: Journal Publications