Autor según el artículo: Dominguez-Lopez, Ines; Parilli-Moser, Isabella; Arancibia-Riveros, Camila; Tresserra-Rimbau, Anna; Martinez-Gonzalez, Miguel Angel; Ortega-Azorin, Carolina; Salas-Salvado, Jordi; Castaner, Olga; Lapetra, Jose; Aros, Fernando; Fiol, Miquel; Serra-Majem, Lluis; Pinto, Xavier; Gomez-Gracia, Enrique; Ros, Emilio; Lamuela-Raventos, Rosa M.; Estruch, Ramon;
Departamento: Bioquímica i Biotecnologia
Autor/es de la URV: Salas Salvadó, Jorge
Palabras clave: Wine Waist to height ratio Waist circumference Very elderly Vegetable consumption Urine sampling Urine level Urine Tartrates Tartaric acid Tandem mass spectrometry Sirtuin 1 Resveratrol Red wine Randomized controlled trials as topic Randomized controlled trial (topic) Randomized controlled trial Questionnaire Predimed Polyphenols Physical activity People by smoking status Oral antidiabetic agent Multicenter study Middle aged Menopause Mediterranean diet Male Major clinical study Low density lipoprotein cholesterol level Low density lipoprotein cholesterol Liquid chromatography-mass spectrometry Liquid chromatography Lipid profile Insulin treatment Insulin Hydroxymethylglutaryl coenzyme a reductase inhibitor Humans Human Heart disease risk factors Health Glucose blood level Glucose Fruit consumption Female Electrospray mass spectrometry Educational status Drinking behavior Diuretic agent Dipeptidyl carboxypeptidase inhibitor Cross-sectional study Cross-sectional studies Coronary-heart-disease Controlled study Consumption Clinical trial Cholesterol, ldl Cholesterol blood level Cholesterol Cardiovascular risk-factors Cardiovascular risk Cardiovascular diseases Cardiovascular disease Caloric intake Body weight Body mass Body fat Blood pressure Blood Biomarkers Biological marker Article Antithrombocytic agent Antilipemic agent Antihypertensive agent Anthropometry Alcohol drinking Alcohol consumption Alcohol Aged, 80 and over Aged Age Adult
Resumen: Postmenopausal women are at higher risk of developing cardiovascular diseases due to changes in lipid profile and body fat, among others. The aim of this study was to evaluate the association of urinary tartaric acid, a biomarker of wine consumption, with anthropometric (weight, waist circumference, body mass index (BMI), and waist-to-height ratio), blood pressure, and biochemical variables (blood glucose and lipid profile) that may be affected during the menopausal transition. This sub-study of the PREDIMED (Prevencion con Dieta Mediterranea) trial included a sample of 230 women aged 60-80 years with high cardiovascular risk at baseline. Urine samples were diluted and filtered, and tartaric acid was analyzed by liquid chromatography coupled to electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS). Correlations between tartaric acid and the study variables were adjusted for age, education level, smoking status, physical activity, BMI, cholesterol-lowering, antihypertensive, and insulin treatment, total energy intake, and consumption of fruits, vegetables, and raisins. A strong association was observed between wine consumption and urinary tartaric acid (0.01 mu g/mg (95% confidence interval (CI): 0.01, 0.01), p-value < 0.001). Total and low-density lipoprotein (LDL) cholesterol were inversely correlated with urinary tartaric acid (-3.13 mu g/mg (-5.54, -0.71), p-value = 0.016 and -3.03 mu g/mg (-5.62, -0.42), p-value = 0.027, respectively), whereas other biochemical and anthropometric variables were unrelated. The results suggest that wine consumption may have a positive effect on cardiovascular health in postmenopausal women, underpinning its nutraceutical properties.
Áreas temáticas: Zootecnia / recursos pesqueiros Saúde coletiva Química Psicología Planejamento urbano e regional / demografia Nutrition and dietetics Nutrition & dietetics Nutrição Medicina veterinaria Medicina iii Medicina ii Medicina i Interdisciplinar Food science Farmacia Engenharias iv Engenharias ii Enfermagem Educação física Economia Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Biotecnología
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
Direcció de correo del autor: jordi.salas@urv.cat
Identificador del autor: 0000-0003-2700-7459
Fecha de alta del registro: 2024-07-27
Volumen de revista: 13
Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
Enlace a la fuente original: https://www.mdpi.com/2072-6643/13/8/2883
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
Referencia al articulo segun fuente origial: Nutrients. 13 (8):
Referencia de l'ítem segons les normes APA: Dominguez-Lopez, Ines; Parilli-Moser, Isabella; Arancibia-Riveros, Camila; Tresserra-Rimbau, Anna; Martinez-Gonzalez, Miguel Angel; Ortega-Azorin, Car (2021). Urinary Tartaric Acid, a Biomarker of Wine Intake, Correlates with Lower Total and LDL Cholesterol. Nutrients, 13(8), -. DOI: 10.3390/nu13082883
DOI del artículo: 10.3390/nu13082883
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2021
Tipo de publicación: Journal Publications
Repositori URV