Autor según el artículo: Avila-Roman, Javier; Garcia-Gil, Sara; Rodriguez-Luna, Azahara; Motilva, Virginia; Talero, Elena;
Departamento: Bioquímica i Biotecnologia
Autor/es de la URV: Ávila Román, Francisco Javier
Palabras clave: Oxidative stress Non-hodgkin-lymphoma Nf-kappa-b Modulating oxidative stress Microalgae Macular pigment density Inflammation High-fat-diet Fucoxanthin induces apoptosis Depressive-like behavior Cell-cycle arrest Carotenoids Cancer Breast-cancer risk Acute lung injury
Resumen: Acute inflammation is a key component of the immune system's response to pathogens, toxic agents, or tissue injury, involving the stimulation of defense mechanisms aimed to removing pathogenic factors and restoring tissue homeostasis. However, uncontrolled acute inflammatory response may lead to chronic inflammation, which is involved in the development of many diseases, including cancer. Nowadays, the need to find new potential therapeutic compounds has raised the worldwide scientific interest to study the marine environment. Specifically, microalgae are considered rich sources of bioactive molecules, such as carotenoids, which are natural isoprenoid pigments with important beneficial effects for health due to their biological activities. Carotenoids are essential nutrients for mammals, but they are unable to synthesize them; instead, a dietary intake of these compounds is required. Carotenoids are classified as carotenes (hydrocarbon carotenoids), such as alpha- and beta-carotene, and xanthophylls (oxygenate derivatives) including zeaxanthin, astaxanthin, fucoxanthin, lutein, alpha- and beta-cryptoxanthin, and canthaxanthin. This review summarizes the present up-to-date knowledge of the anti-inflammatory and anticancer activities of microalgal carotenoids both in vitro and in vivo, as well as the latest status of human studies for their potential use in prevention and treatment of inflammatory diseases and cancer.</p>
Áreas temáticas: Zootecnia / recursos pesqueiros Química Pharmacology, toxicology and pharmaceutics (miscellaneous) Pharmacology & pharmacy Pharmaceutical science Nutrição Medicina veterinaria Medicina iii Medicina ii Medicina i Interdisciplinar Geociências Farmacia Engenharias iii Engenharias ii Educação física Drug discovery Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Chemistry, medicinal Biotecnología Biodiversidade Astronomia / física
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
Direcció de correo del autor: franciscojavier.avila@urv.cat
Identificador del autor: 0000-0001-9766-8178
Fecha de alta del registro: 2024-07-27
Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
Enlace a la fuente original: https://www.mdpi.com/1660-3397/19/10/531
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
Referencia al articulo segun fuente origial: Marine Drugs. 19 (10):
Referencia de l'ítem segons les normes APA: Avila-Roman, Javier; Garcia-Gil, Sara; Rodriguez-Luna, Azahara; Motilva, Virginia; Talero, Elena; (2021). Anti-Inflammatory and Anticancer Effects of Microalgal Carotenoids. Marine Drugs, 19(10), -. DOI: 10.3390/md19100531
DOI del artículo: 10.3390/md19100531
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2021
Tipo de publicación: Journal Publications