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Multiresidue analytical method for high production volume chemicals in dust samples, occurrence and human exposure assessment

  • Datos identificativos

    Identificador: imarina:9261623
    Autores:
    Nunez, MireiaFontanals, NuriaBorrull, FrancescMarcie, Rosa Maria
    Resumen:
    A multiresidue analytical method based on pressurised liquid extraction and gas-chromatography mass spectrometry was developed to determine 22 compounds belonging to different chemical families in indoor dust: seven organophosphate esters, six phthalate esters, three benzotriazoles, five benzothiazoles and four benzenesulfonamides were included in the present study, all of them belonging to the category of high production volume chemicals (HPVCs). Apparent recoveries ranged between 45% and 123% and method quantification limits ranged from 0.03 μg/g to 3.8 μg/g. The occurrence of the selected HPVCs was evaluated in indoor dust from different locations in the Tarragona (Catalonia, Spain) region. Two benzenesulfonamides, ortho-toluenesulfonamide and para-toluenesulfonamide, were detected in dust samples for the first time. Phthalate esters and organophosphate esters were the most abundant compounds found, and di-(2-ethylhexyl) phthalate (DEHP) was determined at the highest concentrations. With the data obtained, human exposure was assessed by calculating the estimated daily intakes (EDI) via ingestion and dermal contact. Non-carcinogenic and carcinogenic risk assessments found no risks in any of the scenarios tested, which included two age classes (children and adults) and two possible exposure scenarios (median and worst-case scenario), except for the evaluation of carcinogen risk due to ingestion of DEHP in the worst-case scenario.Copyright © 2022. Published by Elsevier Ltd.
  • Otros:

    Autor según el artículo: Nunez, Mireia; Fontanals, Nuria; Borrull, Francesc; Marcie, Rosa Maria
    Departamento: Química Analítica i Química Orgànica
    Autor/es de la URV: Borrull Ballarín, Francesc / Fontanals Torroja, Núria / Marcé Recasens, Rosa Maria / NÚÑEZ MARCÉ, MIREIA
    Palabras clave: Risk assessment Pressurised liquid extraction Organophosphate flame retardants Indoor dust Human exposure High production volume chemicals Gas chromatography-mass spectrometry risk assessment pressurised liquid extraction plasticizers phthalate multi-residue method indoor dust human exposure house-dust gas chromatography-mass spectrometry extraction esters barcelona
    Resumen: A multiresidue analytical method based on pressurised liquid extraction and gas-chromatography mass spectrometry was developed to determine 22 compounds belonging to different chemical families in indoor dust: seven organophosphate esters, six phthalate esters, three benzotriazoles, five benzothiazoles and four benzenesulfonamides were included in the present study, all of them belonging to the category of high production volume chemicals (HPVCs). Apparent recoveries ranged between 45% and 123% and method quantification limits ranged from 0.03 μg/g to 3.8 μg/g. The occurrence of the selected HPVCs was evaluated in indoor dust from different locations in the Tarragona (Catalonia, Spain) region. Two benzenesulfonamides, ortho-toluenesulfonamide and para-toluenesulfonamide, were detected in dust samples for the first time. Phthalate esters and organophosphate esters were the most abundant compounds found, and di-(2-ethylhexyl) phthalate (DEHP) was determined at the highest concentrations. With the data obtained, human exposure was assessed by calculating the estimated daily intakes (EDI) via ingestion and dermal contact. Non-carcinogenic and carcinogenic risk assessments found no risks in any of the scenarios tested, which included two age classes (children and adults) and two possible exposure scenarios (median and worst-case scenario), except for the evaluation of carcinogen risk due to ingestion of DEHP in the worst-case scenario.Copyright © 2022. Published by Elsevier Ltd.
    Áreas temáticas: Zootecnia / recursos pesqueiros Saúde coletiva Química Public health, environmental and occupational health Pollution Odontología Nutrição Medicine (miscellaneous) Medicina veterinaria Medicina ii Medicina i Materiais Interdisciplinar Health, toxicology and mutagenesis Geociências General chemistry Farmacia Environmental sciences Environmental engineering Environmental chemistry Ensino Engenharias iii Engenharias ii Engenharias i Educação física Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Chemistry (miscellaneous) Chemistry (all) Biotecnología Biodiversidade Astronomia / física
    Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
    Direcció de correo del autor: nuria.fontanals@urv.cat nuria.fontanals@urv.cat rosamaria.marce@urv.cat francesc.borrull@urv.cat
    Identificador del autor: 0000-0002-7534-1964 0000-0002-7534-1964 0000-0002-5667-2899 0000-0003-2718-9336
    Fecha de alta del registro: 2024-10-12
    Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
    Enlace a la fuente original: https://www.sciencedirect.com/science/article/pii/S0045653522011328
    URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
    Referencia al articulo segun fuente origial: Chemosphere. 301 134639-134639
    Referencia de l'ítem segons les normes APA: Nunez, Mireia; Fontanals, Nuria; Borrull, Francesc; Marcie, Rosa Maria (2022). Multiresidue analytical method for high production volume chemicals in dust samples, occurrence and human exposure assessment. Chemosphere, 301(), 134639-134639. DOI: 10.1016/j.chemosphere.2022.134639
    DOI del artículo: 10.1016/j.chemosphere.2022.134639
    Entidad: Universitat Rovira i Virgili
    Año de publicación de la revista: 2022
    Tipo de publicación: Journal Publications
  • Palabras clave:

    Chemistry (Miscellaneous),Environmental Chemistry,Environmental Engineering,Environmental Sciences,Health, Toxicology and Mutagenesis,Medicine (Miscellaneous),Pollution,Public Health, Environmental and Occupational Health
    Risk assessment
    Pressurised liquid extraction
    Organophosphate flame retardants
    Indoor dust
    Human exposure
    High production volume chemicals
    Gas chromatography-mass spectrometry
    risk assessment
    pressurised liquid extraction
    plasticizers
    phthalate
    multi-residue method
    indoor dust
    human exposure
    house-dust
    gas chromatography-mass spectrometry
    extraction
    esters
    barcelona
    Zootecnia / recursos pesqueiros
    Saúde coletiva
    Química
    Public health, environmental and occupational health
    Pollution
    Odontología
    Nutrição
    Medicine (miscellaneous)
    Medicina veterinaria
    Medicina ii
    Medicina i
    Materiais
    Interdisciplinar
    Health, toxicology and mutagenesis
    Geociências
    General chemistry
    Farmacia
    Environmental sciences
    Environmental engineering
    Environmental chemistry
    Ensino
    Engenharias iii
    Engenharias ii
    Engenharias i
    Educação física
    Ciências biológicas iii
    Ciências biológicas ii
    Ciências biológicas i
    Ciências ambientais
    Ciências agrárias i
    Ciência de alimentos
    Chemistry (miscellaneous)
    Chemistry (all)
    Biotecnología
    Biodiversidade
    Astronomia / física
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